Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004013 | molecular_function | adenosylhomocysteinase activity |
| B | 0004013 | molecular_function | adenosylhomocysteinase activity |
| C | 0004013 | molecular_function | adenosylhomocysteinase activity |
| D | 0004013 | molecular_function | adenosylhomocysteinase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue ADN A 501 |
| Chain | Residue |
| A | LEU55 |
| A | ASP193 |
| A | HIS304 |
| A | THR354 |
| A | HIS356 |
| A | MET361 |
| A | PHE365 |
| A | NAD502 |
| A | HIS56 |
| A | THR58 |
| A | GLN60 |
| A | THR61 |
| A | ASP134 |
| A | GLU159 |
| A | THR160 |
| A | LYS189 |
| site_id | AC2 |
| Number of Residues | 29 |
| Details | binding site for residue NAD A 502 |
| Chain | Residue |
| A | THR160 |
| A | THR161 |
| A | THR162 |
| A | ASN194 |
| A | GLY225 |
| A | ASP226 |
| A | VAL227 |
| A | THR245 |
| A | GLU246 |
| A | ILE247 |
| A | ASP248 |
| A | CYS251 |
| A | THR279 |
| A | GLY280 |
| A | ASN281 |
| A | ILE284 |
| A | ILE302 |
| A | GLY303 |
| A | HIS304 |
| A | LEU347 |
| A | ASN349 |
| A | HIS356 |
| A | ADN501 |
| A | HOH623 |
| A | HOH724 |
| A | HOH738 |
| B | LYS429 |
| B | TYR433 |
| B | HOH683 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue NA A 503 |
| Chain | Residue |
| A | GLN60 |
| A | THR354 |
| A | GLY355 |
| A | HIS356 |
| A | HOH729 |
| A | HOH768 |
| A | HOH812 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue PG4 A 504 |
| Chain | Residue |
| A | LYS381 |
| A | TYR382 |
| A | TYR387 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | binding site for residue ADN B 501 |
| Chain | Residue |
| B | HIS56 |
| B | THR58 |
| B | GLN60 |
| B | THR61 |
| B | ASP134 |
| B | GLU159 |
| B | THR160 |
| B | LYS189 |
| B | ASP193 |
| B | HIS304 |
| B | THR354 |
| B | HIS356 |
| B | MET361 |
| B | PHE365 |
| B | NAD502 |
| site_id | AC6 |
| Number of Residues | 29 |
| Details | binding site for residue NAD B 502 |
| Chain | Residue |
| A | LYS429 |
| A | TYR433 |
| B | THR160 |
| B | THR161 |
| B | THR162 |
| B | ASN194 |
| B | GLY225 |
| B | ASP226 |
| B | VAL227 |
| B | THR245 |
| B | GLU246 |
| B | ILE247 |
| B | ASP248 |
| B | CYS251 |
| B | THR279 |
| B | GLY280 |
| B | ASN281 |
| B | ILE284 |
| B | ILE302 |
| B | GLY303 |
| B | HIS304 |
| B | ASN349 |
| B | HIS356 |
| B | ADN501 |
| B | HOH603 |
| B | HOH623 |
| B | HOH688 |
| B | HOH728 |
| B | HOH812 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue NA B 503 |
| Chain | Residue |
| B | GLN60 |
| B | THR354 |
| B | GLY355 |
| B | HIS356 |
| B | HOH729 |
| B | HOH805 |
| B | HOH814 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue PEG B 504 |
| Chain | Residue |
| A | LYS38 |
| A | GLU39 |
| B | ARG399 |
| B | ASP425 |
| site_id | AC9 |
| Number of Residues | 16 |
| Details | binding site for residue ADN C 501 |
| Chain | Residue |
| C | HIS56 |
| C | THR58 |
| C | GLN60 |
| C | THR61 |
| C | ASP134 |
| C | GLU159 |
| C | THR160 |
| C | LYS189 |
| C | ASP193 |
| C | HIS304 |
| C | LEU347 |
| C | THR354 |
| C | HIS356 |
| C | MET361 |
| C | PHE365 |
| C | NAD502 |
| site_id | AD1 |
| Number of Residues | 27 |
| Details | binding site for residue NAD C 502 |
| Chain | Residue |
| C | THR160 |
| C | THR161 |
| C | THR162 |
| C | ASN194 |
| C | GLY223 |
| C | GLY225 |
| C | ASP226 |
| C | VAL227 |
| C | THR245 |
| C | GLU246 |
| C | ILE247 |
| C | ASP248 |
| C | CYS251 |
| C | THR279 |
| C | ASN281 |
| C | ILE284 |
| C | ILE302 |
| C | GLY303 |
| C | HIS304 |
| C | ASN349 |
| C | HIS356 |
| C | ADN501 |
| C | HOH601 |
| C | HOH603 |
| C | HOH615 |
| D | LYS429 |
| D | TYR433 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue NA C 503 |
| Chain | Residue |
| C | GLN60 |
| C | THR354 |
| C | HIS356 |
| C | HOH621 |
| C | HOH660 |
| C | HOH667 |
| site_id | AD3 |
| Number of Residues | 15 |
| Details | binding site for residue ADN D 501 |
| Chain | Residue |
| D | HIS56 |
| D | THR58 |
| D | GLN60 |
| D | THR61 |
| D | ASP134 |
| D | GLU159 |
| D | THR160 |
| D | LYS189 |
| D | ASP193 |
| D | HIS304 |
| D | THR354 |
| D | HIS356 |
| D | MET361 |
| D | PHE365 |
| D | NAD502 |
| site_id | AD4 |
| Number of Residues | 29 |
| Details | binding site for residue NAD D 502 |
| Chain | Residue |
| C | GLN416 |
| C | LYS429 |
| C | TYR433 |
| C | HOH620 |
| D | THR160 |
| D | THR161 |
| D | THR162 |
| D | ASN194 |
| D | GLY225 |
| D | ASP226 |
| D | VAL227 |
| D | THR245 |
| D | GLU246 |
| D | ILE247 |
| D | ASP248 |
| D | CYS251 |
| D | THR279 |
| D | GLY280 |
| D | ASN281 |
| D | ILE284 |
| D | ILE302 |
| D | GLY303 |
| D | HIS304 |
| D | LEU347 |
| D | ASN349 |
| D | HIS356 |
| D | ADN501 |
| D | HOH606 |
| D | HOH637 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue NA D 503 |
| Chain | Residue |
| D | GLN60 |
| D | THR354 |
| D | HIS356 |
| D | HOH645 |
| D | HOH680 |
Functional Information from PROSITE/UniProt
| site_id | PS00738 |
| Number of Residues | 15 |
| Details | ADOHCYASE_1 S-adenosyl-L-homocysteine hydrolase signature 1. SCNiFSTQDhAAAAI |
| Chain | Residue | Details |
| A | SER79-ILE93 | |
| site_id | PS00739 |
| Number of Residues | 18 |
| Details | ADOHCYASE_2 S-adenosyl-L-homocysteine hydrolase signature 2. GKvavVaGYGdVGKGsaA |
| Chain | Residue | Details |
| A | GLY216-ALA233 | |
