6G9X
Crystal structure of a MFS transporter at 2.54 Angstroem resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0015293 | molecular_function | symporter activity |
| A | 0022857 | molecular_function | transmembrane transporter activity |
| A | 0055085 | biological_process | transmembrane transport |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0015293 | molecular_function | symporter activity |
| B | 0022857 | molecular_function | transmembrane transporter activity |
| B | 0055085 | biological_process | transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 128 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:31201333 |
| Chain | Residue | Details |
| A | MET1-ARG10 | |
| A | TRP130-ARG133 | |
| A | PHE188-ASP227 | |
| A | GLY291-ILE292 | |
| A | GLY347-ALA350 | |
| A | THR404-ALA412 | |
| B | MET1-ARG10 | |
| B | TRP130-ARG133 | |
| B | PHE188-ASP227 | |
| B | GLY291-ILE292 | |
| B | GLY347-ALA350 | |
| B | THR404-ALA412 | |
| A | GLY75 | |
| B | GLY75 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 610 |
| Details | TRANSMEM: Helical => ECO:0000269|PubMed:31201333 |
| Chain | Residue | Details |
| A | TRP11-ALA40 | |
| A | ARG46-MET74 | |
| A | PRO76-GLY95 | |
| A | LYS100-TRP129 | |
| A | ARG134-ILE160 | |
| A | ARG168-ALA187 | |
| A | THR228-ASP257 | |
| A | ALA262-ILE290 | |
| A | ARG293-LEU313 | |
| A | VAL317-TYR346 | |
| A | GLN351-THR380 | |
| A | TYR383-MET403 | |
| B | TRP11-ALA40 | |
| B | ARG46-MET74 | |
| B | PRO76-GLY95 | |
| B | LYS100-TRP129 | |
| B | ARG134-ILE160 | |
| B | ARG168-ALA187 | |
| B | THR228-ASP257 | |
| B | ALA262-ILE290 | |
| B | ARG293-LEU313 | |
| B | VAL317-TYR346 | |
| B | GLN351-THR380 | |
| B | TYR383-MET403 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 38 |
| Details | TOPO_DOM: Periplasmic => ECO:0000269|PubMed:31201333 |
| Chain | Residue | Details |
| A | GLU41-SER45 | |
| A | PHE96-SER99 | |
| A | GLU161-TRP167 | |
| A | ALA258-THR261 | |
| A | GLY314-SER316 | |
| A | GLY381-THR382 | |
| B | GLU41-SER45 | |
| B | PHE96-SER99 | |
| B | GLU161-TRP167 | |
| B | ALA258-THR261 | |
| B | GLY314-SER316 | |
| B | GLY381-THR382 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:31201333 |
| Chain | Residue | Details |
| A | TYR119 | |
| A | ARG280 | |
| B | TYR119 | |
| B | ARG280 |
