6G9V
Crystal structure of Aspergillus fumigatus UDP-N-acetylglucosamine pyrophosphorylase(AfUAP1) in complex with UDPGlcNAc, pyrophosphate and Mg2+
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003977 | molecular_function | UDP-N-acetylglucosamine diphosphorylase activity |
| A | 0006048 | biological_process | UDP-N-acetylglucosamine biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070569 | molecular_function | uridylyltransferase activity |
| B | 0003977 | molecular_function | UDP-N-acetylglucosamine diphosphorylase activity |
| B | 0006048 | biological_process | UDP-N-acetylglucosamine biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0070569 | molecular_function | uridylyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 34 |
| Details | binding site for residue UD1 B 601 |
| Chain | Residue |
| B | MET134 |
| B | ASN249 |
| B | CYS277 |
| B | VAL278 |
| B | ASP279 |
| B | VAL315 |
| B | GLY316 |
| B | GLU329 |
| B | TYR330 |
| B | ASN355 |
| B | VAL357 |
| B | ALA135 |
| B | PHE409 |
| B | PHE411 |
| B | PHE433 |
| B | LYS437 |
| B | PPV602 |
| B | MG603 |
| B | HOH716 |
| B | HOH743 |
| B | HOH756 |
| B | HOH773 |
| B | GLY136 |
| B | HOH780 |
| B | HOH789 |
| B | HOH806 |
| B | HOH850 |
| B | HOH903 |
| B | GLY137 |
| B | ARG141 |
| B | MET191 |
| B | GLN222 |
| B | PRO246 |
| B | GLY248 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue PPV B 602 |
| Chain | Residue |
| B | GLY137 |
| B | GLN138 |
| B | GLY139 |
| B | THR140 |
| B | ARG141 |
| B | UD1601 |
| B | MG603 |
| B | HOH716 |
| B | HOH717 |
| B | HOH753 |
| B | HOH756 |
| B | HOH779 |
| B | HOH780 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 603 |
| Chain | Residue |
| B | UD1601 |
| B | PPV602 |
| B | HOH780 |
| B | HOH903 |
