6G9V
Crystal structure of Aspergillus fumigatus UDP-N-acetylglucosamine pyrophosphorylase(AfUAP1) in complex with UDPGlcNAc, pyrophosphate and Mg2+
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003977 | molecular_function | UDP-N-acetylglucosamine diphosphorylase activity |
A | 0006048 | biological_process | UDP-N-acetylglucosamine biosynthetic process |
A | 0016740 | molecular_function | transferase activity |
A | 0016779 | molecular_function | nucleotidyltransferase activity |
A | 0043934 | biological_process | sporulation |
A | 0070569 | molecular_function | uridylyltransferase activity |
B | 0003977 | molecular_function | UDP-N-acetylglucosamine diphosphorylase activity |
B | 0006048 | biological_process | UDP-N-acetylglucosamine biosynthetic process |
B | 0016740 | molecular_function | transferase activity |
B | 0016779 | molecular_function | nucleotidyltransferase activity |
B | 0043934 | biological_process | sporulation |
B | 0070569 | molecular_function | uridylyltransferase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 34 |
Details | binding site for residue UD1 B 601 |
Chain | Residue |
B | MET134 |
B | ASN249 |
B | CYS277 |
B | VAL278 |
B | ASP279 |
B | VAL315 |
B | GLY316 |
B | GLU329 |
B | TYR330 |
B | ASN355 |
B | VAL357 |
B | ALA135 |
B | PHE409 |
B | PHE411 |
B | PHE433 |
B | LYS437 |
B | PPV602 |
B | MG603 |
B | HOH716 |
B | HOH743 |
B | HOH756 |
B | HOH773 |
B | GLY136 |
B | HOH780 |
B | HOH789 |
B | HOH806 |
B | HOH850 |
B | HOH903 |
B | GLY137 |
B | ARG141 |
B | MET191 |
B | GLN222 |
B | PRO246 |
B | GLY248 |
site_id | AC2 |
Number of Residues | 13 |
Details | binding site for residue PPV B 602 |
Chain | Residue |
B | GLY137 |
B | GLN138 |
B | GLY139 |
B | THR140 |
B | ARG141 |
B | UD1601 |
B | MG603 |
B | HOH716 |
B | HOH717 |
B | HOH753 |
B | HOH756 |
B | HOH779 |
B | HOH780 |
site_id | AC3 |
Number of Residues | 4 |
Details | binding site for residue MG B 603 |
Chain | Residue |
B | UD1601 |
B | PPV602 |
B | HOH780 |
B | HOH903 |