6G9F

Structural basis for the inhibition of E. coli PBP2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008658	molecular_function	penicillin binding
A	0009002	molecular_function	serine-type D-Ala-D-Ala carboxypeptidase activity
A	0009252	biological_process	peptidoglycan biosynthetic process
A	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue NXL A 1330

Chain	Residue
A	ALA329
A	THR547
A	HOH709
A	HOH738
A	SER330
A	LYS333
A	TRP370
A	SER387
A	ASP389
A	ILE453
A	SER545
A	GLY546

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Acyl-ester intermediate => ECO:0000255|HAMAP-Rule:MF_02081, ECO:0000269|PubMed:30995398, ECO:0000269|PubMed:3148617, ECO:0000269|PubMed:37620344

Chain	Residue	Details
A	SER330

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