6G9F

Structural basis for the inhibition of E. coli PBP2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008658	molecular_function	penicillin binding
A	0009002	molecular_function	serine-type D-Ala-D-Ala carboxypeptidase activity
A	0009252	biological_process	peptidoglycan biosynthetic process
A	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue NXL A 1330

Chain	Residue
A	ALA329
A	THR547
A	HOH709
A	HOH738
A	SER330
A	LYS333
A	TRP370
A	SER387
A	ASP389
A	ILE453
A	SER545
A	GLY546

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Acyl-ester intermediate","evidences":[{"source":"HAMAP-Rule","id":"MF_02081","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"30995398","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"3148617","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"37620344","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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