6G8V

Crystal structure of the light chain of botulinum neurotoxin X (residues 2-442)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004222	molecular_function	metalloendopeptidase activity
A	0006508	biological_process	proteolysis
A	0008270	molecular_function	zinc ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue ZN A 501

Chain	Residue
A	HIS227
A	HIS231
A	GLU266
A	HOH640
A	HOH815

---

site_id	AC2
Number of Residues	9
Details	binding site for residue GOL A 502

Chain	Residue
A	GLN399
A	HOH721
A	HOH733
A	HOH810
A	HOH848
A	ARG26
A	ASP29
A	LEU170
A	ASN201

---

site_id	AC3
Number of Residues	8
Details	binding site for residue GOL A 503

Chain	Residue
A	GLU348
A	ARG360
A	GOL505
A	HOH626
A	HOH653
A	HOH671
A	HOH741
A	HOH808

---

site_id	AC4
Number of Residues	10
Details	binding site for residue GOL A 504

Chain	Residue
A	ASP15
A	GLY272
A	SER275
A	LYS276
A	PHE344
A	ASN347
A	ASN350
A	HOH619
A	HOH802
A	HOH878

---

site_id	AC5
Number of Residues	8
Details	binding site for residue GOL A 505

Chain	Residue
A	LYS193
A	PRO194
A	PRO219
A	ARG360
A	LYS365
A	GOL503
A	HOH671
A	HOH782

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"evidences":[{"source":"UniProtKB","id":"P0DPI0","evidenceCode":"ECO:0000250"},{"source":"PROSITE-ProRule","id":"PRU10095","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10095","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"29540745","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6F47","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"29540745","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6F47","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---