Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004089 | molecular_function | carbonate dehydratase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| B | 0004089 | molecular_function | carbonate dehydratase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| C | 0004089 | molecular_function | carbonate dehydratase activity |
| C | 0008270 | molecular_function | zinc ion binding |
| D | 0004089 | molecular_function | carbonate dehydratase activity |
| D | 0008270 | molecular_function | zinc ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 301 |
| Chain | Residue |
| A | HIS91 |
| A | HIS93 |
| A | HIS117 |
| A | EOQ303 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | ASP156 |
| A | SER160 |
| A | HOH447 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | binding site for residue EOQ A 303 |
| Chain | Residue |
| A | GLN89 |
| A | HIS91 |
| A | HIS93 |
| A | HIS117 |
| A | SER130 |
| A | VAL141 |
| A | LEU197 |
| A | THR198 |
| A | THR199 |
| A | TRP208 |
| A | ZN301 |
| A | HOH407 |
| A | HOH412 |
| A | HOH426 |
| A | HOH500 |
| A | TRP4 |
| A | ASN64 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 301 |
| Chain | Residue |
| B | HIS91 |
| B | HIS93 |
| B | HIS117 |
| B | EOQ305 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 302 |
| Chain | Residue |
| B | THR44 |
| B | LEU46 |
| B | GLY80 |
| B | TYR190 |
| B | ARG192 |
| B | HOH423 |
| B | HOH601 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 303 |
| Chain | Residue |
| B | ASP156 |
| B | SER160 |
| B | GLN221 |
| B | ALA224 |
| B | HOH519 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 304 |
| Chain | Residue |
| B | LYS57 |
| B | GLN58 |
| B | HOH404 |
| B | HOH632 |
| site_id | AC8 |
| Number of Residues | 15 |
| Details | binding site for residue EOQ B 305 |
| Chain | Residue |
| B | ASN64 |
| B | GLN89 |
| B | HIS91 |
| B | HIS93 |
| B | HIS117 |
| B | SER130 |
| B | SER133 |
| B | VAL141 |
| B | LEU197 |
| B | THR198 |
| B | THR199 |
| B | TRP208 |
| B | ZN301 |
| B | HOH403 |
| B | HOH581 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue ZN C 301 |
| Chain | Residue |
| C | HIS91 |
| C | HIS93 |
| C | HIS117 |
| C | EOQ305 |
| site_id | AD1 |
| Number of Residues | 8 |
| Details | binding site for residue EDO C 302 |
| Chain | Residue |
| C | SER42 |
| C | LEU46 |
| C | GLY80 |
| C | LEU81 |
| C | TYR190 |
| C | ARG192 |
| C | HOH418 |
| C | HOH445 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 303 |
| Chain | Residue |
| C | LEU46 |
| C | GLU47 |
| C | PHE48 |
| C | GLU180 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 304 |
| Chain | Residue |
| C | ASN71 |
| C | LEU72 |
| C | THR88 |
| C | HOH433 |
| C | HOH439 |
| C | HOH527 |
| site_id | AD4 |
| Number of Residues | 17 |
| Details | binding site for residue EOQ C 305 |
| Chain | Residue |
| C | TRP4 |
| C | ASN64 |
| C | GLN89 |
| C | HIS91 |
| C | HIS93 |
| C | HIS117 |
| C | VAL119 |
| C | SER130 |
| C | SER133 |
| C | VAL141 |
| C | LEU197 |
| C | THR198 |
| C | THR199 |
| C | TRP208 |
| C | ZN301 |
| C | HOH403 |
| C | HOH548 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN D 301 |
| Chain | Residue |
| D | HIS93 |
| D | HIS117 |
| D | EOQ307 |
| D | HIS91 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 302 |
| Chain | Residue |
| D | SER42 |
| D | THR44 |
| D | LEU46 |
| D | GLY80 |
| D | TYR190 |
| D | ARG192 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 303 |
| Chain | Residue |
| D | GLN110 |
| D | HIS111 |
| D | PHE112 |
| D | EDO304 |
| D | HOH417 |
| D | HOH612 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 304 |
| Chain | Residue |
| D | PHE112 |
| D | ALA113 |
| D | GLU147 |
| D | MET148 |
| D | EDO303 |
| D | HOH508 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 305 |
| Chain | Residue |
| D | PRO100 |
| D | HIS101 |
| D | MET148 |
| D | HOH508 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 306 |
| Chain | Residue |
| D | ASP156 |
| D | SER160 |
| D | HOH541 |
| site_id | AE2 |
| Number of Residues | 15 |
| Details | binding site for residue EOQ D 307 |
| Chain | Residue |
| D | ASN64 |
| D | GLN89 |
| D | HIS91 |
| D | HIS93 |
| D | HIS117 |
| D | SER130 |
| D | SER133 |
| D | VAL141 |
| D | LEU197 |
| D | THR198 |
| D | THR199 |
| D | TRP208 |
| D | ZN301 |
| D | HOH402 |
| D | HOH544 |
Functional Information from PROSITE/UniProt
| site_id | PS00162 |
| Number of Residues | 17 |
| Details | ALPHA_CA_1 Alpha-carbonic anhydrases signature. SEHtVsgqhFaaELHIV |
| Chain | Residue | Details |
| A | SER103-VAL119 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS66 | |
| B | HIS66 | |
| C | HIS66 | |
| D | HIS66 | |
| Chain | Residue | Details |
| A | HIS91 | |
| D | HIS91 | |
| D | HIS93 | |
| D | HIS117 | |
| A | HIS93 | |
| A | HIS117 | |
| B | HIS91 | |
| B | HIS93 | |
| B | HIS117 | |
| C | HIS91 | |
| C | HIS93 | |
| C | HIS117 | |
| Chain | Residue | Details |
| A | THR198 | |
| B | THR198 | |
| C | THR198 | |
| D | THR198 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN52 | |
| A | ASN134 | |
| B | ASN52 | |
| B | ASN134 | |
| C | ASN52 | |
| C | ASN134 | |
| D | ASN52 | |
| D | ASN134 | |
