6G4N
Torpedo californica acetylcholinesterase bound to uncharged hybrid reactivator 2
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0001507 | biological_process | acetylcholine catabolic process in synaptic cleft |
A | 0003990 | molecular_function | acetylcholinesterase activity |
A | 0004104 | molecular_function | cholinesterase activity |
A | 0005615 | cellular_component | extracellular space |
A | 0005886 | cellular_component | plasma membrane |
A | 0006581 | biological_process | acetylcholine catabolic process |
A | 0019695 | biological_process | choline metabolic process |
A | 0043083 | cellular_component | synaptic cleft |
A | 0045202 | cellular_component | synapse |
A | 0052689 | molecular_function | carboxylic ester hydrolase activity |
A | 0098552 | cellular_component | side of membrane |
B | 0001507 | biological_process | acetylcholine catabolic process in synaptic cleft |
B | 0003990 | molecular_function | acetylcholinesterase activity |
B | 0004104 | molecular_function | cholinesterase activity |
B | 0005615 | cellular_component | extracellular space |
B | 0005886 | cellular_component | plasma membrane |
B | 0006581 | biological_process | acetylcholine catabolic process |
B | 0019695 | biological_process | choline metabolic process |
B | 0043083 | cellular_component | synaptic cleft |
B | 0045202 | cellular_component | synapse |
B | 0052689 | molecular_function | carboxylic ester hydrolase activity |
B | 0098552 | cellular_component | side of membrane |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Acyl-ester intermediate |
Chain | Residue | Details |
A | SER200 | |
B | SER200 |
site_id | SWS_FT_FI2 |
Number of Residues | 4 |
Details | ACT_SITE: Charge relay system |
Chain | Residue | Details |
A | GLU327 | |
A | HIS440 | |
B | GLU327 | |
B | HIS440 |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:10368299, ECO:0000269|PubMed:16763558 |
Chain | Residue | Details |
A | ASN59 | |
B | ASN59 |
site_id | SWS_FT_FI4 |
Number of Residues | 2 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:10368299, ECO:0000269|PubMed:16763558, ECO:0000269|PubMed:1678899 |
Chain | Residue | Details |
A | ASN416 | |
B | ASN416 |
site_id | SWS_FT_FI5 |
Number of Residues | 4 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:10368299 |
Chain | Residue | Details |
A | ASN457 | |
A | ASN533 | |
B | ASN457 | |
B | ASN533 |