6G3F

Crystal structure of EDDS lyase in complex with fumarate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004056	molecular_function	argininosuccinate lyase activity
A	0005829	cellular_component	cytosol
A	0006526	biological_process	L-arginine biosynthetic process
A	0016829	molecular_function	lyase activity
A	0042450	biological_process	L-arginine biosynthetic process via ornithine

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue FUM A 601

Chain	Residue
A	SER111
A	LYS286
A	ASN288
A	ARG112
A	ASN113
A	THR158
A	GLN159
A	SER280
A	SER281
A	ILE282
A	MET283

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site_id	AC2
Number of Residues	5
Details	binding site for residue PEG A 602

Chain	Residue
A	TRP208
A	ASP369
A	ASP372
A	ARG376
A	ARG442

---

site_id	AC3
Number of Residues	3
Details	binding site for residue PEG A 603

Chain	Residue
A	GLN438
A	ARG442
A	GLU444

---

site_id	AC4
Number of Residues	5
Details	binding site for residue PEG A 604

Chain	Residue
A	ARG187
A	GLU464
A	LYS467
A	ASP468
A	HOH872

---

site_id	AC5
Number of Residues	5
Details	binding site for residue PEG A 605

Chain	Residue
A	LYS145
A	HIS149
A	LEU349
A	HIS350
A	HOH933

---

site_id	AC6
Number of Residues	3
Details	binding site for residue PEG A 606

Chain	Residue
A	TYR42
A	GLN45
A	LYS483

---

site_id	AC7
Number of Residues	6
Details	binding site for residue PEG A 607

Chain	Residue
A	GLU133
A	ILE136
A	GLY137
A	GLU140
A	HOH759
A	HOH876

---

site_id	AC8
Number of Residues	4
Details	binding site for residue PEG A 608

Chain	Residue
A	ARG13
A	ASP265
A	GLN268
A	HOH864

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site_id	AC9
Number of Residues	4
Details	binding site for residue PEG A 609

Chain	Residue
A	ALA80
A	THR81
A	ARG86
A	HOH752

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