6G2J

Mouse mitochondrial complex I in the active state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
A	0006979	biological_process	response to oxidative stress
A	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
A	0009060	biological_process	aerobic respiration
A	0009642	biological_process	response to light intensity
A	0009725	biological_process	response to hormone
A	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
A	0045271	cellular_component	respiratory chain complex I
A	0071385	biological_process	cellular response to glucocorticoid stimulus
A	1902600	biological_process	proton transmembrane transport
B	0003954	molecular_function	NADH dehydrogenase activity
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
B	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
B	0009060	biological_process	aerobic respiration
B	0016491	molecular_function	oxidoreductase activity
B	0032981	biological_process	mitochondrial respiratory chain complex I assembly
B	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
B	0045271	cellular_component	respiratory chain complex I
B	0046872	molecular_function	metal ion binding
B	0048038	molecular_function	quinone binding
B	0051536	molecular_function	iron-sulfur cluster binding
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding
B	1902600	biological_process	proton transmembrane transport
C	0003954	molecular_function	NADH dehydrogenase activity
C	0005515	molecular_function	protein binding
C	0005739	cellular_component	mitochondrion
C	0005743	cellular_component	mitochondrial inner membrane
C	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
C	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
C	0009060	biological_process	aerobic respiration
C	0016491	molecular_function	oxidoreductase activity
C	0016604	cellular_component	nuclear body
C	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
C	0031966	cellular_component	mitochondrial membrane
C	0032981	biological_process	mitochondrial respiratory chain complex I assembly
C	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
C	0043209	cellular_component	myelin sheath
C	0045271	cellular_component	respiratory chain complex I
C	0072593	biological_process	reactive oxygen species metabolic process
C	1902600	biological_process	proton transmembrane transport
D	0003954	molecular_function	NADH dehydrogenase activity
D	0005515	molecular_function	protein binding
D	0005654	cellular_component	nucleoplasm
D	0005739	cellular_component	mitochondrion
D	0005743	cellular_component	mitochondrial inner membrane
D	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
D	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
D	0009060	biological_process	aerobic respiration
D	0016491	molecular_function	oxidoreductase activity
D	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
D	0019826	molecular_function	oxygen sensor activity
D	0022008	biological_process	neurogenesis
D	0031625	molecular_function	ubiquitin protein ligase binding
D	0032981	biological_process	mitochondrial respiratory chain complex I assembly
D	0042063	biological_process	gliogenesis
D	0042775	biological_process	mitochondrial ATP synthesis coupled electron transport
D	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
D	0045271	cellular_component	respiratory chain complex I
D	0046872	molecular_function	metal ion binding
D	0048038	molecular_function	quinone binding
D	0051287	molecular_function	NAD binding
D	0051539	molecular_function	4 iron, 4 sulfur cluster binding
D	0061351	biological_process	neural precursor cell proliferation
D	0071453	biological_process	cellular response to oxygen levels
D	1902600	biological_process	proton transmembrane transport
E	0005739	cellular_component	mitochondrion
E	0005743	cellular_component	mitochondrial inner membrane
E	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
E	0007399	biological_process	nervous system development
E	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
E	0009060	biological_process	aerobic respiration
E	0016491	molecular_function	oxidoreductase activity
E	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
E	0043209	cellular_component	myelin sheath
E	0045271	cellular_component	respiratory chain complex I
E	0046872	molecular_function	metal ion binding
E	0048738	biological_process	cardiac muscle tissue development
E	0051537	molecular_function	2 iron, 2 sulfur cluster binding
E	1902600	biological_process	proton transmembrane transport
F	0005515	molecular_function	protein binding
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0005829	cellular_component	cytosol
F	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
F	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
F	0009060	biological_process	aerobic respiration
F	0010181	molecular_function	FMN binding
F	0016491	molecular_function	oxidoreductase activity
F	0042775	biological_process	mitochondrial ATP synthesis coupled electron transport
F	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
F	0045271	cellular_component	respiratory chain complex I
F	0046872	molecular_function	metal ion binding
F	0051287	molecular_function	NAD binding
F	0051539	molecular_function	4 iron, 4 sulfur cluster binding
F	1902600	biological_process	proton transmembrane transport
G	0005515	molecular_function	protein binding
G	0005739	cellular_component	mitochondrion
G	0005743	cellular_component	mitochondrial inner membrane
G	0005758	cellular_component	mitochondrial intermembrane space
G	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
G	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
G	0009055	molecular_function	electron transfer activity
G	0009060	biological_process	aerobic respiration
G	0016020	cellular_component	membrane
G	0016491	molecular_function	oxidoreductase activity
G	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
G	0032981	biological_process	mitochondrial respiratory chain complex I assembly
G	0042773	biological_process	ATP synthesis coupled electron transport
G	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
G	0043209	cellular_component	myelin sheath
G	0045271	cellular_component	respiratory chain complex I
G	0045333	biological_process	cellular respiration
G	0046872	molecular_function	metal ion binding
G	0051536	molecular_function	iron-sulfur cluster binding
G	0051537	molecular_function	2 iron, 2 sulfur cluster binding
G	0051539	molecular_function	4 iron, 4 sulfur cluster binding
G	1902600	biological_process	proton transmembrane transport
H	0001666	biological_process	response to hypoxia
H	0005739	cellular_component	mitochondrion
H	0005743	cellular_component	mitochondrial inner membrane
H	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
H	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
H	0009060	biological_process	aerobic respiration
H	0009410	biological_process	response to xenobiotic stimulus
H	0014070	biological_process	response to organic cyclic compound
H	0016020	cellular_component	membrane
H	0030425	cellular_component	dendrite
H	0031966	cellular_component	mitochondrial membrane
H	0032981	biological_process	mitochondrial respiratory chain complex I assembly
H	0033194	biological_process	response to hydroperoxide
H	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
H	0043025	cellular_component	neuronal cell body
H	0045271	cellular_component	respiratory chain complex I
H	1902600	biological_process	proton transmembrane transport
I	0003954	molecular_function	NADH dehydrogenase activity
I	0005515	molecular_function	protein binding
I	0005739	cellular_component	mitochondrion
I	0005743	cellular_component	mitochondrial inner membrane
I	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
I	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
I	0009060	biological_process	aerobic respiration
I	0016020	cellular_component	membrane
I	0016491	molecular_function	oxidoreductase activity
I	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
I	0032981	biological_process	mitochondrial respiratory chain complex I assembly
I	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
I	0045271	cellular_component	respiratory chain complex I
I	0046872	molecular_function	metal ion binding
I	0051539	molecular_function	4 iron, 4 sulfur cluster binding
I	1902600	biological_process	proton transmembrane transport
J	0005739	cellular_component	mitochondrion
J	0005743	cellular_component	mitochondrial inner membrane
J	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
J	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
J	0009060	biological_process	aerobic respiration
J	0032981	biological_process	mitochondrial respiratory chain complex I assembly
J	0035094	biological_process	response to nicotine
J	0042220	biological_process	response to cocaine
J	0042542	biological_process	response to hydrogen peroxide
J	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
J	1902600	biological_process	proton transmembrane transport
K	0005739	cellular_component	mitochondrion
K	0005743	cellular_component	mitochondrial inner membrane
K	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
K	0009060	biological_process	aerobic respiration
K	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
K	0042773	biological_process	ATP synthesis coupled electron transport
K	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
K	0045271	cellular_component	respiratory chain complex I
K	1902600	biological_process	proton transmembrane transport
L	0001666	biological_process	response to hypoxia
L	0005739	cellular_component	mitochondrion
L	0005743	cellular_component	mitochondrial inner membrane
L	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
L	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
L	0009060	biological_process	aerobic respiration
L	0032981	biological_process	mitochondrial respiratory chain complex I assembly
L	0042542	biological_process	response to hydrogen peroxide
L	0042773	biological_process	ATP synthesis coupled electron transport
L	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
L	0045271	cellular_component	respiratory chain complex I
L	1902600	biological_process	proton transmembrane transport
M	0001666	biological_process	response to hypoxia
M	0001701	biological_process	in utero embryonic development
M	0005739	cellular_component	mitochondrion
M	0005743	cellular_component	mitochondrial inner membrane
M	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
M	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
M	0009060	biological_process	aerobic respiration
M	0021549	biological_process	cerebellum development
M	0032981	biological_process	mitochondrial respiratory chain complex I assembly
M	0035094	biological_process	response to nicotine
M	0042773	biological_process	ATP synthesis coupled electron transport
M	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
M	0045271	cellular_component	respiratory chain complex I
M	0045471	biological_process	response to ethanol
M	1902600	biological_process	proton transmembrane transport
N	0005739	cellular_component	mitochondrion
N	0005743	cellular_component	mitochondrial inner membrane
N	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
N	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
N	0009060	biological_process	aerobic respiration
N	0032981	biological_process	mitochondrial respiratory chain complex I assembly
N	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
N	0045271	cellular_component	respiratory chain complex I
N	0072593	biological_process	reactive oxygen species metabolic process
N	1902600	biological_process	proton transmembrane transport
O	0005739	cellular_component	mitochondrion
O	0005743	cellular_component	mitochondrial inner membrane
O	0005759	cellular_component	mitochondrial matrix
O	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
O	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
O	0009060	biological_process	aerobic respiration
O	0032981	biological_process	mitochondrial respiratory chain complex I assembly
O	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
O	0043209	cellular_component	myelin sheath
O	0045271	cellular_component	respiratory chain complex I
O	1902600	biological_process	proton transmembrane transport
P	0003954	molecular_function	NADH dehydrogenase activity
P	0005515	molecular_function	protein binding
P	0005739	cellular_component	mitochondrion
P	0005743	cellular_component	mitochondrial inner membrane
P	0005759	cellular_component	mitochondrial matrix
P	0007623	biological_process	circadian rhythm
P	0009060	biological_process	aerobic respiration
P	0031966	cellular_component	mitochondrial membrane
P	0032981	biological_process	mitochondrial respiratory chain complex I assembly
P	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
P	0044877	molecular_function	protein-containing complex binding
P	0045271	cellular_component	respiratory chain complex I
Q	0003016	biological_process	respiratory system process
Q	0005739	cellular_component	mitochondrion
Q	0005743	cellular_component	mitochondrial inner membrane
Q	0006099	biological_process	tricarboxylic acid cycle
Q	0006954	biological_process	inflammatory response
Q	0007420	biological_process	brain development
Q	0007601	biological_process	visual perception
Q	0007605	biological_process	sensory perception of sound
Q	0007628	biological_process	adult walking behavior
Q	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
Q	0009060	biological_process	aerobic respiration
Q	0014876	biological_process	response to injury involved in regulation of muscle adaptation
Q	0022900	biological_process	electron transport chain
Q	0022904	biological_process	respiratory electron transport chain
Q	0030534	biological_process	adult behavior
Q	0032981	biological_process	mitochondrial respiratory chain complex I assembly
Q	0036343	biological_process	psychomotor behavior
Q	0042417	biological_process	dopamine metabolic process
Q	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
Q	0045087	biological_process	innate immune response
Q	0045271	cellular_component	respiratory chain complex I
Q	0048666	biological_process	neuron development
Q	0050890	biological_process	cognition
Q	0051402	biological_process	neuron apoptotic process
Q	0051881	biological_process	regulation of mitochondrial membrane potential
Q	0071453	biological_process	cellular response to oxygen levels
Q	0072593	biological_process	reactive oxygen species metabolic process
Q	1902600	biological_process	proton transmembrane transport
R	0001822	biological_process	kidney development
R	0003674	molecular_function	molecular_function
R	0005739	cellular_component	mitochondrion
R	0005743	cellular_component	mitochondrial inner membrane
R	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
R	0006631	biological_process	fatty acid metabolic process
R	0006936	biological_process	muscle contraction
R	0007005	biological_process	mitochondrion organization
R	0009060	biological_process	aerobic respiration
R	0010467	biological_process	gene expression
R	0017145	biological_process	stem cell division
R	0022904	biological_process	respiratory electron transport chain
R	0030330	biological_process	DNA damage response, signal transduction by p53 class mediator
R	0032981	biological_process	mitochondrial respiratory chain complex I assembly
R	0035264	biological_process	multicellular organism growth
R	0042391	biological_process	regulation of membrane potential
R	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
R	0045271	cellular_component	respiratory chain complex I
R	0051881	biological_process	regulation of mitochondrial membrane potential
R	0061458	biological_process	reproductive system development
R	0072359	biological_process	circulatory system development
R	0072497	biological_process	mesenchymal stem cell differentiation
R	0072593	biological_process	reactive oxygen species metabolic process
R	0090398	biological_process	cellular senescence
R	0097168	biological_process	mesenchymal stem cell proliferation
S	0001835	biological_process	blastocyst hatching
S	0005739	cellular_component	mitochondrion
S	0005743	cellular_component	mitochondrial inner membrane
S	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
S	0009060	biological_process	aerobic respiration
S	0031966	cellular_component	mitochondrial membrane
S	0032981	biological_process	mitochondrial respiratory chain complex I assembly
S	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
S	0045271	cellular_component	respiratory chain complex I
S	1902600	biological_process	proton transmembrane transport
T	0005654	cellular_component	nucleoplasm
T	0005739	cellular_component	mitochondrion
T	0005743	cellular_component	mitochondrial inner membrane
T	0006633	biological_process	fatty acid biosynthetic process
T	0009060	biological_process	aerobic respiration
T	0009249	biological_process	protein lipoylation
T	0016226	biological_process	iron-sulfur cluster assembly
T	0019752	biological_process	carboxylic acid metabolic process
T	0032981	biological_process	mitochondrial respiratory chain complex I assembly
T	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
T	0044571	biological_process	[2Fe-2S] cluster assembly
T	0045271	cellular_component	respiratory chain complex I
T	0099128	cellular_component	mitochondrial [2Fe-2S] assembly complex
T	0140978	molecular_function	mitochondrial large ribosomal subunit binding
T	1902494	cellular_component	catalytic complex
T	1990229	cellular_component	iron-sulfur cluster assembly complex
U	0005654	cellular_component	nucleoplasm
U	0005739	cellular_component	mitochondrion
U	0005743	cellular_component	mitochondrial inner membrane
U	0006633	biological_process	fatty acid biosynthetic process
U	0009060	biological_process	aerobic respiration
U	0009249	biological_process	protein lipoylation
U	0016226	biological_process	iron-sulfur cluster assembly
U	0019752	biological_process	carboxylic acid metabolic process
U	0032981	biological_process	mitochondrial respiratory chain complex I assembly
U	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
U	0044571	biological_process	[2Fe-2S] cluster assembly
U	0045271	cellular_component	respiratory chain complex I
U	0099128	cellular_component	mitochondrial [2Fe-2S] assembly complex
U	0140978	molecular_function	mitochondrial large ribosomal subunit binding
U	1902494	cellular_component	catalytic complex
U	1990229	cellular_component	iron-sulfur cluster assembly complex
V	0005739	cellular_component	mitochondrion
V	0005743	cellular_component	mitochondrial inner membrane
V	0009060	biological_process	aerobic respiration
V	0022904	biological_process	respiratory electron transport chain
V	0032981	biological_process	mitochondrial respiratory chain complex I assembly
V	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
V	0045271	cellular_component	respiratory chain complex I
W	0003674	molecular_function	molecular_function
W	0005739	cellular_component	mitochondrion
W	0005743	cellular_component	mitochondrial inner membrane
W	0009060	biological_process	aerobic respiration
W	0031966	cellular_component	mitochondrial membrane
W	0032981	biological_process	mitochondrial respiratory chain complex I assembly
W	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
W	0045271	cellular_component	respiratory chain complex I
X	0005739	cellular_component	mitochondrion
X	0005743	cellular_component	mitochondrial inner membrane
X	0005758	cellular_component	mitochondrial intermembrane space
X	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
X	0009060	biological_process	aerobic respiration
X	0032981	biological_process	mitochondrial respiratory chain complex I assembly
X	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
X	0044877	molecular_function	protein-containing complex binding
X	0045271	cellular_component	respiratory chain complex I
Y	0005739	cellular_component	mitochondrion
Y	0005743	cellular_component	mitochondrial inner membrane
Y	0032981	biological_process	mitochondrial respiratory chain complex I assembly
Y	0045271	cellular_component	respiratory chain complex I
Z	0005524	molecular_function	ATP binding
Z	0005634	cellular_component	nucleus
Z	0005654	cellular_component	nucleoplasm
Z	0005737	cellular_component	cytoplasm
Z	0005739	cellular_component	mitochondrion
Z	0005743	cellular_component	mitochondrial inner membrane
Z	0006915	biological_process	apoptotic process
Z	0009060	biological_process	aerobic respiration
Z	0031966	cellular_component	mitochondrial membrane
Z	0032981	biological_process	mitochondrial respiratory chain complex I assembly
Z	0035458	biological_process	cellular response to interferon-beta
Z	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
Z	0045039	biological_process	protein insertion into mitochondrial inner membrane
Z	0045271	cellular_component	respiratory chain complex I
Z	0045732	biological_process	positive regulation of protein catabolic process
Z	0045892	biological_process	negative regulation of DNA-templated transcription
Z	0071300	biological_process	cellular response to retinoic acid
Z	0097191	biological_process	extrinsic apoptotic signaling pathway
Z	0098803	cellular_component	respiratory chain complex
Z	1900119	biological_process	positive regulation of execution phase of apoptosis
a	0005739	cellular_component	mitochondrion
a	0005743	cellular_component	mitochondrial inner membrane
a	0009060	biological_process	aerobic respiration
a	0031966	cellular_component	mitochondrial membrane
a	0032981	biological_process	mitochondrial respiratory chain complex I assembly
a	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
a	0045271	cellular_component	respiratory chain complex I
b	0003674	molecular_function	molecular_function
b	0005739	cellular_component	mitochondrion
b	0005743	cellular_component	mitochondrial inner membrane
b	0009060	biological_process	aerobic respiration
b	0032981	biological_process	mitochondrial respiratory chain complex I assembly
b	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
b	0045271	cellular_component	respiratory chain complex I
c	0003674	molecular_function	molecular_function
c	0005739	cellular_component	mitochondrion
c	0005743	cellular_component	mitochondrial inner membrane
c	0009060	biological_process	aerobic respiration
c	0032981	biological_process	mitochondrial respiratory chain complex I assembly
c	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
c	0045271	cellular_component	respiratory chain complex I
d	0005737	cellular_component	cytoplasm
d	0005739	cellular_component	mitochondrion
d	0005743	cellular_component	mitochondrial inner membrane
d	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
d	0009060	biological_process	aerobic respiration
d	0032981	biological_process	mitochondrial respiratory chain complex I assembly
d	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
d	0045271	cellular_component	respiratory chain complex I
e	0003674	molecular_function	molecular_function
e	0005739	cellular_component	mitochondrion
e	0005743	cellular_component	mitochondrial inner membrane
e	0005758	cellular_component	mitochondrial intermembrane space
e	0009060	biological_process	aerobic respiration
e	0032981	biological_process	mitochondrial respiratory chain complex I assembly
e	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
e	0045271	cellular_component	respiratory chain complex I
f	0005739	cellular_component	mitochondrion
f	0005743	cellular_component	mitochondrial inner membrane
f	0009060	biological_process	aerobic respiration
f	0016607	cellular_component	nuclear speck
f	0032981	biological_process	mitochondrial respiratory chain complex I assembly
f	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
f	0045271	cellular_component	respiratory chain complex I
g	0003674	molecular_function	molecular_function
g	0005739	cellular_component	mitochondrion
g	0005743	cellular_component	mitochondrial inner membrane
g	0009060	biological_process	aerobic respiration
g	0032981	biological_process	mitochondrial respiratory chain complex I assembly
g	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
g	0045271	cellular_component	respiratory chain complex I
h	0003674	molecular_function	molecular_function
h	0005654	cellular_component	nucleoplasm
h	0005739	cellular_component	mitochondrion
h	0005743	cellular_component	mitochondrial inner membrane
h	0009060	biological_process	aerobic respiration
h	0032981	biological_process	mitochondrial respiratory chain complex I assembly
h	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
h	0045271	cellular_component	respiratory chain complex I
i	0005654	cellular_component	nucleoplasm
i	0005739	cellular_component	mitochondrion
i	0005743	cellular_component	mitochondrial inner membrane
i	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
i	0009060	biological_process	aerobic respiration
i	0031966	cellular_component	mitochondrial membrane
i	0032981	biological_process	mitochondrial respiratory chain complex I assembly
i	0042775	biological_process	mitochondrial ATP synthesis coupled electron transport
i	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
i	0045271	cellular_component	respiratory chain complex I
j	0003674	molecular_function	molecular_function
j	0005739	cellular_component	mitochondrion
j	0005743	cellular_component	mitochondrial inner membrane
j	0009060	biological_process	aerobic respiration
j	0032981	biological_process	mitochondrial respiratory chain complex I assembly
j	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
j	0045271	cellular_component	respiratory chain complex I
k	0003674	molecular_function	molecular_function
k	0005739	cellular_component	mitochondrion
k	0005743	cellular_component	mitochondrial inner membrane
k	0009060	biological_process	aerobic respiration
k	0022900	biological_process	electron transport chain
k	0032981	biological_process	mitochondrial respiratory chain complex I assembly
k	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
k	0045271	cellular_component	respiratory chain complex I
l	0003674	molecular_function	molecular_function
l	0005739	cellular_component	mitochondrion
l	0005743	cellular_component	mitochondrial inner membrane
l	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
l	0009060	biological_process	aerobic respiration
l	0032981	biological_process	mitochondrial respiratory chain complex I assembly
l	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
l	0045271	cellular_component	respiratory chain complex I
m	0003674	molecular_function	molecular_function
m	0005654	cellular_component	nucleoplasm
m	0005739	cellular_component	mitochondrion
m	0005743	cellular_component	mitochondrial inner membrane
m	0009060	biological_process	aerobic respiration
m	0032981	biological_process	mitochondrial respiratory chain complex I assembly
m	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
m	0045271	cellular_component	respiratory chain complex I
n	0005739	cellular_component	mitochondrion
n	0005743	cellular_component	mitochondrial inner membrane
n	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
n	0009060	biological_process	aerobic respiration
n	0032981	biological_process	mitochondrial respiratory chain complex I assembly
n	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
n	0045271	cellular_component	respiratory chain complex I
o	0003674	molecular_function	molecular_function
o	0005739	cellular_component	mitochondrion
o	0005743	cellular_component	mitochondrial inner membrane
o	0005758	cellular_component	mitochondrial intermembrane space
o	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
o	0009060	biological_process	aerobic respiration
o	0032981	biological_process	mitochondrial respiratory chain complex I assembly
o	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
o	0045271	cellular_component	respiratory chain complex I
o	1902600	biological_process	proton transmembrane transport
p	0005739	cellular_component	mitochondrion
p	0005743	cellular_component	mitochondrial inner membrane
p	0009060	biological_process	aerobic respiration
p	0032981	biological_process	mitochondrial respiratory chain complex I assembly
p	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
p	0045271	cellular_component	respiratory chain complex I
q	0003674	molecular_function	molecular_function
q	0005739	cellular_component	mitochondrion
q	0005743	cellular_component	mitochondrial inner membrane
q	0009060	biological_process	aerobic respiration
q	0016020	cellular_component	membrane
q	0032981	biological_process	mitochondrial respiratory chain complex I assembly
q	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
q	0045271	cellular_component	respiratory chain complex I
r	0005739	cellular_component	mitochondrion
r	0005743	cellular_component	mitochondrial inner membrane
r	0009060	biological_process	aerobic respiration
r	0042773	biological_process	ATP synthesis coupled electron transport
r	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
r	0045271	cellular_component	respiratory chain complex I
s	0005739	cellular_component	mitochondrion
s	0005743	cellular_component	mitochondrial inner membrane
s	0009060	biological_process	aerobic respiration
s	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
s	0045271	cellular_component	respiratory chain complex I

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue 3PE A 201

Chain	Residue
J	ALA20
J	LEU21
J	PHE91
K	LEU17
K	MET21
K	PHE22
K	ARG23

---

site_id	AC2
Number of Residues	9
Details	binding site for residue SF4 B 201

Chain	Residue
B	CYS65
B	SER128
B	CYS129
B	CYS159
B	PRO160
D	ARG105
D	HIS190
B	ALA63
B	CYS64

---

site_id	AC3
Number of Residues	8
Details	binding site for residue FES E 301

Chain	Residue
E	CYS103
E	THR105
E	PRO107
E	CYS108
E	CYS144
E	LEU145
E	CYS148
F	PRO102

---

site_id	AC4
Number of Residues	14
Details	binding site for residue FMN F 501

Chain	Residue
F	GLY67
F	ARG68
F	GLY69
F	LYS78
F	ASN96
F	ASP98
F	GLU99
F	TYR184
F	ILE185
F	GLY187
F	ASN224
F	THR227
F	ALA406
F	LEU407

---

site_id	AC5
Number of Residues	7
Details	binding site for residue SF4 F 502

Chain	Residue
F	ILE185
F	PRO203
F	CYS359
F	GLN361
F	CYS362
F	CYS365
F	CYS405

---

site_id	AC6
Number of Residues	7
Details	binding site for residue SF4 G 801

Chain	Residue
G	HIS101
G	CYS105
G	CYS108
G	GLN110
G	CYS114
G	GLN117
G	GLY206

---

site_id	AC7
Number of Residues	7
Details	binding site for residue SF4 G 802

Chain	Residue
G	CYS153
G	ILE154
G	GLN155
G	CYS156
G	THR157
G	CYS159
G	CYS203

---

site_id	AC8
Number of Residues	7
Details	binding site for residue FES G 803

Chain	Residue
G	ARG39
G	CYS41
G	GLY50
G	CYS52
G	ARG53
G	CYS55
G	CYS69

---

site_id	AC9
Number of Residues	19
Details	binding site for residue 3PE H 401

Chain	Residue
A	TYR4
A	ILE7
A	PHE8
A	ILE11
H	THR76
H	LEU81
H	LEU98
H	ASN99
H	PHE104
H	THR108
H	PC1402
J	PHE37
J	LEU41
J	LEU44
J	PHE56
Z	PHE139
Z	THR140
Z	TRP141
a	ALA39

---

site_id	AD1
Number of Residues	9
Details	binding site for residue PC1 H 402

Chain	Residue
H	SER67
H	MET68
H	SER69
H	ILE73
H	3PE401
J	LEU30
J	TRP82
J	GLY83
P	ARG251

---

site_id	AD2
Number of Residues	14
Details	binding site for residue 3PE H 403

Chain	Residue
H	LEU288
H	ASN292
H	PHE293
H	LEU296
H	TRP303
I	LEU27
I	TRP29
I	LEU32
Z	ILE39
D	ARG233
H	TRP179
H	ALA182
H	PHE186
H	ILE273

---

site_id	AD3
Number of Residues	12
Details	binding site for residue PC1 H 404

Chain	Residue
H	MET183
I	ASP21
I	THR30
I	ILE33
I	ARG34
I	GLY37
Z	ARG27
Z	GLY28
Z	LEU29
Z	SER30
Z	MET34
r	TRP13

---

site_id	AD4
Number of Residues	14
Details	binding site for residue CDL H 405

Chain	Residue
H	TYR43
a	MET1
a	TRP2
a	PHE3
a	LEU6
q	LEU3
q	VAL6
q	ARG9
q	GLY10
q	GLN13
r	SER2
r	THR4
r	VAL6
r	ILE7

---

site_id	AD5
Number of Residues	10
Details	binding site for residue PC1 H 406

Chain	Residue
B	ASP45
B	LEU46
B	TRP49
B	ARG52
H	ILE39
H	VAL40
H	LEU46
q	ARG29
q	ASN31
q	TRP75

---

site_id	AD6
Number of Residues	9
Details	binding site for residue SF4 I 201

Chain	Residue
I	HIS67
I	CYS89
I	CYS118
I	ILE119
I	TYR120
I	CYS121
I	GLY122
I	CYS124
I	GLU135

---

site_id	AD7
Number of Residues	9
Details	binding site for residue SF4 I 202

Chain	Residue
I	CYS79
I	ILE80
I	ALA81
I	CYS82
I	LEU84
I	CYS85
I	ILE96
I	CYS128
I	ILE133

---

site_id	AD8
Number of Residues	9
Details	binding site for residue 3PE L 701

Chain	Residue
L	GLN170
L	LEU173
L	TYR174
L	GLY228
L	LEU229
L	ILE533
L	HIS534
l	ASN86
l	ARG87

---

site_id	AD9
Number of Residues	18
Details	binding site for residue CDL L 702

Chain	Residue
L	SER22
L	MET23
L	ARG116
L	LYS119
L	TYR120
L	LEU123
L	ILE142
L	MET150
L	LEU153
L	CDL703
L	3PE704
M	PRO353
M	THR357
g	LEU68
h	LEU22
h	MET25
h	GLY33
h	ILE37

---

site_id	AE1
Number of Residues	17
Details	binding site for residue CDL L 703

Chain	Residue
L	TRP66
L	ASN136
L	PHE138
L	CDL702
L	3PE704
M	3PE503
g	THR73
g	ALA76
h	THR41
h	ASN44
h	ILE45
h	GLU49
h	HIS69
i	TRP79
i	TYR83
i	HIS88
p	ARG48

---

site_id	AE2
Number of Residues	9
Details	binding site for residue 3PE L 704

Chain	Residue
L	THR65
L	TRP66
L	CDL702
L	CDL703
h	GLU49
i	PHE80
i	TYR84
i	HIS88
i	LYS92

---

site_id	AE3
Number of Residues	10
Details	binding site for residue 3PE M 501

Chain	Residue
D	TYR20
L	ILE562
L	LYS564
L	SER567
L	HIS570
M	ILE155
M	VAL212
N	MET284
N	MET285
N	PHE291

---

site_id	AE4
Number of Residues	7
Details	binding site for residue 3PE M 502

Chain	Residue
M	ILE162
M	LEU166
M	SER191
N	LEU276
N	ILE277
N	THR280
Y	TRP132

---

site_id	AE5
Number of Residues	10
Details	binding site for residue 3PE M 503

Chain	Residue
L	TRP66
L	CDL703
M	TRP71
M	PRO371
M	ILE445
M	LEU446
M	LEU447
M	THR449
M	SER450
g	THR72

---

site_id	AE6
Number of Residues	12
Details	binding site for residue 3PE M 504

Chain	Residue
M	LYS3
M	LEU33
M	LEU36
M	THR40
f	PHE19
f	CYS23
f	ARG27
g	PHE62
g	ILE66
g	PHE70
h	PHE79
h	TYR80

---

site_id	AE7
Number of Residues	13
Details	binding site for residue 3PE M 505

Chain	Residue
M	TRP16
M	ASN88
M	SER97
M	MET98
M	3PE506
N	TRP234
N	PRO238
N	LEU241
N	LEU246
N	SER301
N	MET304
O	ASN294
d	MET47

---

site_id	AE8
Number of Residues	7
Details	binding site for residue 3PE M 506

Chain	Residue
M	TRP16
M	3PE505
O	LYS303
d	CYS40
d	LEU43
d	VAL53
d	ARG55

---

site_id	AE9
Number of Residues	13
Details	binding site for residue CDL M 507

Chain	Residue
M	MET55
M	ILE120
N	PRO256
N	LEU337
X	TRP169
X	THR170
X	VAL171
d	ASN27
d	PRO29
d	TYR33
f	PHE21
f	LYS28
f	LYS32

---

site_id	AF1
Number of Residues	10
Details	binding site for residue 3PE N 401

Chain	Residue
L	LEU576
L	ILE598
N	MET156
N	THR160
N	MET164
Y	GLY35
Y	TYR38
Y	SER39
Y	ASN43
Y	TYR58

---

site_id	AF2
Number of Residues	11
Details	binding site for residue ADP O 401

Chain	Residue
O	ILE31
O	CYS32
O	GLY34
O	ASN36
O	TYR83
O	GLN97
O	LEU100
O	ARG104
O	PHE134
O	GLU191
O	TYR198

---

site_id	AF3
Number of Residues	11
Details	binding site for residue PC1 P 401

Chain	Residue
A	GLN26
B	ILE47
B	LEU183
B	ILE185
B	TRP186
B	ARG189
H	MET53
H	PHE56
P	ASP55
P	PHE275
P	GLU276

---

site_id	AF4
Number of Residues	18
Details	binding site for residue NDP P 501

Chain	Residue
B	ARG189
P	THR27
P	GLY28
P	PHE29
P	ARG50
P	CYS51
P	LEU94
P	ILE95
P	GLY96
P	ARG97
P	PHE104
P	VAL109
P	VAL132
P	HIS134
P	LYS149
P	SER169
P	ILE171
P	ARG177

---

site_id	AF5
Number of Residues	4
Details	binding site for residue ZN R 201

Chain	Residue
R	CYS59
R	HIS68
R	CYS84
R	CYS87

---

site_id	AF6
Number of Residues	11
Details	binding site for residue EHZ T 201

Chain	Residue
T	SER44
W	LYS31
W	THR48
W	ILE56
W	GLY61
W	PHE69
W	ALA73
W	VAL75
W	GLU91
W	VAL105
W	PHE108

---

site_id	AF7
Number of Residues	13
Details	binding site for residue EHZ U 201

Chain	Residue
U	ASP43
U	SER44
n	HIS11
n	GLN12
n	VAL15
n	ARG46
n	PHE47
n	HIS50
n	LYS51
n	ALA66
n	GLU69
n	PHE70
n	ASN73

---

Functional Information from PROSITE/UniProt

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGLDSLDQVEIIMAM

Chain	Residue	Details
T	ASP39-MET54

---

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DIDAEKLMCpqEI

Chain	Residue	Details
T	ASP64-ILE76

---

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiACKlCEaICP

Chain	Residue	Details
I	CYS79-PRO90
I	CYS118-PRO129

---

site_id	PS00535
Number of Residues	12
Details	COMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGtEKLiEyK

Chain	Residue	Details
D	LEU83-LYS94

---

site_id	PS00542
Number of Residues	22
Details	COMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREvwDMFgvfffnHpdlRrIL

Chain	Residue	Details
C	GLU131-LEU152

---

site_id	PS00641
Number of Residues	18
Details	COMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PrfCYherlsvaGnCRmC

Chain	Residue	Details
G	PRO38-CYS55

---

site_id	PS00642
Number of Residues	13
Details	COMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPiCDqGGeCdLQ

Chain	Residue	Details
G	CYS105-GLN117

---

site_id	PS00643
Number of Residues	11
Details	COMPLEX1_75K_3 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. RCIqCtRCIrF

Chain	Residue	Details
G	ARG152-PHE162

---

site_id	PS00644
Number of Residues	16
Details	COMPLEX1_51K_1 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. GAGAYICGEETALIES

Chain	Residue	Details
F	GLY180-SER195

---

site_id	PS00645
Number of Residues	12
Details	COMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGqCtPCReG

Chain	Residue	Details
F	GLU357-GLY368

---

site_id	PS00667
Number of Residues	16
Details	COMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GILQpFaDAMKLFmKE

Chain	Residue	Details
H	GLY44-GLU59

---

site_id	PS00668
Number of Residues	14
Details	COMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLTEGEseLVs.G

Chain	Residue	Details
H	PRO197-GLY210

---

site_id	PS01099
Number of Residues	19
Details	COMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DklFTlieveCLGaCvnAP

Chain	Residue	Details
E	ASP134-PRO152

---

site_id	PS01150
Number of Residues	17
Details	COMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GcDRIVPVDIYvPgCPP

Chain	Residue	Details
B	GLY145-PRO161

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P56181

Chain	Residue	Details
s	SER66
N	LEU324-ILE344
M	MET350-PRO370
M	THR392-ILE412
M	LEU434-ILE454
L	LEU457-ILE477
L	MET482-LEU502
L	LEU586-LEU606
U	LYS20
N	ALA56-LEU76
N	GLY92-TRP114
N	LEU149-ASN171
N	ILE178-PRO198
N	LEU200-MET220
N	LEU241-LEU261
N	ASN274-THR294

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:O96000

Chain	Residue	Details
p	SER150
V	LYS59
G	CYS108
G	CYS114

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21183079

Chain	Residue	Details
m	SER25
k	HIS12
k	HIS14
G	LYS686

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0007744|PubMed:23806337

Chain	Residue	Details
k	LYS28
k	LYS39

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0007744|PubMed:23806337

Chain	Residue	Details
V	LYS97

---