6G1O

Structure of Pseudomonas aeruginosa Isocitrate Lyase, ICL

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004451	molecular_function	isocitrate lyase activity
A	0006097	biological_process	glyoxylate cycle
A	0006099	biological_process	tricarboxylic acid cycle
A	0016829	molecular_function	lyase activity
A	0019752	biological_process	carboxylic acid metabolic process
A	0046872	molecular_function	metal ion binding
A	1900232	biological_process	negative regulation of single-species biofilm formation on inanimate substrate

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue CA A 501

Chain	Residue
A	ASP184
A	ASP186
A	GLV502
A	HOH601
A	HOH602
A	HOH623

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site_id	AC2
Number of Residues	7
Details	binding site for residue GLV A 502

Chain	Residue
A	GLU213
A	SER217
A	CA501
A	HOH601
A	ASP117
A	SER119
A	ASP186

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000250|UniProtKB:P0A9G6

Chain	Residue	Details
A	CYS222

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P0A9G6

Chain	Residue	Details
A	SER101
A	ASP184

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site_id	SWS_FT_FI3
Number of Residues	3
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P9WKK7

Chain	Residue	Details
A	GLY223
A	ASN380
A	THR451

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