6G1H
Amine Dehydrogenase from Petrotoga mobilis; open form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0008839 | molecular_function | 4-hydroxy-tetrahydrodipicolinate reductase activity |
| A | 0009089 | biological_process | L-lysine biosynthetic process via diaminopimelate |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0047530 | molecular_function | 2,4-diaminopentanoate dehydrogenase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 35 |
| Details | binding site for residue NAD A 401 |
| Chain | Residue |
| A | TRP7 |
| A | ARG35 |
| A | ALA75 |
| A | THR76 |
| A | ASN77 |
| A | SER78 |
| A | GLN86 |
| A | ILE100 |
| A | GLU102 |
| A | THR132 |
| A | VAL134 |
| A | GLY8 |
| A | ASN135 |
| A | PRO136 |
| A | GLN187 |
| A | THR303 |
| A | HOH513 |
| A | HOH526 |
| A | HOH530 |
| A | HOH532 |
| A | HOH559 |
| A | HOH562 |
| A | PHE9 |
| A | HOH595 |
| A | HOH600 |
| A | HOH601 |
| A | HOH606 |
| A | HOH611 |
| A | HOH653 |
| A | GLY10 |
| A | ALA11 |
| A | MET12 |
| A | HIS32 |
| A | ASP33 |
| A | PHE34 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 402 |
| Chain | Residue |
| A | ASN135 |
| A | ARG161 |
| A | HIS264 |
| A | GLY299 |
| A | HOH562 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 403 |
| Chain | Residue |
| A | ILE162 |
| A | VAL275 |
| A | GLN276 |
| A | HOH547 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 404 |
| Chain | Residue |
| A | GLU223 |
| A | PRO224 |
| A | ILE225 |
| A | ASN247 |
| A | HOH618 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"journal article","publicationDate":"2019","firstPage":"324","lastPage":"333","volume":"2","journal":"Nat. Catal.","title":"A family of native amine dehydrogenases for the asymmetric reductive amination of ketones.","authors":["Mayol O.","Bastard K.","Beloti L.","Frese A.","Turkenburg J.P.","Petit J.-L.","Mariage A.","Debard A.","Pellouin V.","Perret A.","de Berardinis V.","Zaparucha A.","Grogan G.","Vergne-Vaxelaire C."],"citationCrossReferences":[{"database":"DOI","id":"10.1038/s41929-019-0249-z"}]}},{"source":"PDB","id":"6G1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6G1M","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"journal article","publicationDate":"2019","firstPage":"324","lastPage":"333","volume":"2","journal":"Nat. Catal.","title":"A family of native amine dehydrogenases for the asymmetric reductive amination of ketones.","authors":["Mayol O.","Bastard K.","Beloti L.","Frese A.","Turkenburg J.P.","Petit J.-L.","Mariage A.","Debard A.","Pellouin V.","Perret A.","de Berardinis V.","Zaparucha A.","Grogan G.","Vergne-Vaxelaire C."],"citationCrossReferences":[{"database":"DOI","id":"10.1038/s41929-019-0249-z"}]}},{"source":"PDB","id":"6G1H","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"journal article","publicationDate":"2019","firstPage":"324","lastPage":"333","volume":"2","journal":"Nat. Catal.","title":"A family of native amine dehydrogenases for the asymmetric reductive amination of ketones.","authors":["Mayol O.","Bastard K.","Beloti L.","Frese A.","Turkenburg J.P.","Petit J.-L.","Mariage A.","Debard A.","Pellouin V.","Perret A.","de Berardinis V.","Zaparucha A.","Grogan G.","Vergne-Vaxelaire C."],"citationCrossReferences":[{"database":"DOI","id":"10.1038/s41929-019-0249-z"}]}},{"source":"PDB","id":"6G1M","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Site: {"description":"Involved in the activation of ammonia","evidences":[{"source":"Reference","evidenceCode":"ECO:0000305","citation":{"citationType":"journal article","publicationDate":"2019","firstPage":"324","lastPage":"333","volume":"2","journal":"Nat. Catal.","title":"A family of native amine dehydrogenases for the asymmetric reductive amination of ketones.","authors":["Mayol O.","Bastard K.","Beloti L.","Frese A.","Turkenburg J.P.","Petit J.-L.","Mariage A.","Debard A.","Pellouin V.","Perret A.","de Berardinis V.","Zaparucha A.","Grogan G.","Vergne-Vaxelaire C."],"citationCrossReferences":[{"database":"DOI","id":"10.1038/s41929-019-0249-z"}]}}]} |
| Chain | Residue | Details |
