6FZG

PPAR gamma mutant complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0004879	molecular_function	nuclear receptor activity
A	0005634	cellular_component	nucleus
A	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue EDK A 550

Chain	Residue
A	PHE310
A	LEU493
A	TYR501
A	HOH660
A	GLY312
A	CYS313
A	GLN314
A	SER317
A	HIS351
A	ILE369
A	PHE391
A	HIS477

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site_id	AC2
Number of Residues	3
Details	binding site for residue CL A 551

Chain	Residue
A	HIS453
A	PRO454
A	GLU455

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG

Chain	Residue	Details
A	GLN342
A	GLU379
A	TYR505

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site_id	SWS_FT_FI2
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649

Chain	Residue	Details
A	MET280

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