6FWS
Structure of DinG in complex with ssDNA and ADPBeF
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003678 | molecular_function | DNA helicase activity |
| A | 0004386 | molecular_function | helicase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| A | 0006281 | biological_process | DNA repair |
| A | 0009432 | biological_process | SOS response |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016818 | molecular_function | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| A | 0033677 | molecular_function | DNA/RNA helicase activity |
| A | 0043139 | molecular_function | 5'-3' DNA helicase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| A | 0160225 | molecular_function | G-quadruplex unwinding activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003678 | molecular_function | DNA helicase activity |
| B | 0004386 | molecular_function | helicase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| B | 0006281 | biological_process | DNA repair |
| B | 0009432 | biological_process | SOS response |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016818 | molecular_function | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0016887 | molecular_function | ATP hydrolysis activity |
| B | 0033677 | molecular_function | DNA/RNA helicase activity |
| B | 0043139 | molecular_function | 5'-3' DNA helicase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051536 | molecular_function | iron-sulfur cluster binding |
| B | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| B | 0160225 | molecular_function | G-quadruplex unwinding activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue SF4 A 801 |
| Chain | Residue |
| A | ARG115 |
| A | CYS120 |
| A | PRO121 |
| A | ARG122 |
| A | CYS205 |
| A | HOH919 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | binding site for residue ADP A 802 |
| Chain | Residue |
| A | GLN31 |
| A | GLY57 |
| A | GLY59 |
| A | LYS60 |
| A | THR61 |
| A | LYS95 |
| A | ASP599 |
| A | LYS601 |
| A | ARG659 |
| A | BEF803 |
| A | MG804 |
| A | HOH935 |
| A | HOH940 |
| A | HOH975 |
| A | HOH977 |
| A | PHE25 |
| A | ILE26 |
| A | ARG28 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue BEF A 803 |
| Chain | Residue |
| A | THR56 |
| A | LYS60 |
| A | GLU249 |
| A | GLY597 |
| A | ARG656 |
| A | ARG659 |
| A | ADP802 |
| A | MG804 |
| A | HOH935 |
| A | HOH956 |
| A | HOH996 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 804 |
| Chain | Residue |
| A | GLU249 |
| A | ADP802 |
| A | BEF803 |
| A | HOH935 |
| A | HOH977 |
| A | HOH979 |
| A | HOH996 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue SF4 B 801 |
| Chain | Residue |
| B | ARG115 |
| B | CYS120 |
| B | PRO121 |
| B | CYS205 |
| B | PHE208 |
| B | HOH1039 |
| site_id | AC6 |
| Number of Residues | 17 |
| Details | binding site for residue ADP B 802 |
| Chain | Residue |
| B | PHE25 |
| B | ILE26 |
| B | ARG28 |
| B | GLN31 |
| B | GLY57 |
| B | GLY59 |
| B | LYS60 |
| B | THR61 |
| B | LEU62 |
| B | LYS95 |
| B | ASP599 |
| B | LYS601 |
| B | ARG659 |
| B | BEF803 |
| B | MG804 |
| B | HOH946 |
| B | HOH951 |
| site_id | AC7 |
| Number of Residues | 13 |
| Details | binding site for residue BEF B 803 |
| Chain | Residue |
| B | THR56 |
| B | LYS60 |
| B | GLU249 |
| B | ALA460 |
| B | GLU596 |
| B | ARG656 |
| B | ARG659 |
| B | ADP802 |
| B | MG804 |
| B | HOH903 |
| B | HOH946 |
| B | HOH954 |
| B | HOH963 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 804 |
| Chain | Residue |
| B | ADP802 |
| B | BEF803 |
| B | HOH946 |
| B | HOH951 |
| B | HOH963 |
| B | HOH1004 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_02205","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"30520735","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19074432","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"6FWS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 113 |
| Details | Region: {"description":"HD1 domain N-terminus","evidences":[{"source":"PubMed","id":"30520735","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 192 |
| Details | Region: {"description":"HD1 domain middle","evidences":[{"source":"PubMed","id":"30520735","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Motif: {"description":"DEAH box","evidences":[{"source":"HAMAP-Rule","id":"MF_02205","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30520735","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"6FWS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
