Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004129 | molecular_function | cytochrome-c oxidase activity |
| A | 0009060 | biological_process | aerobic respiration |
| A | 0016020 | cellular_component | membrane |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0020037 | molecular_function | heme binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 1902600 | biological_process | proton transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | binding site for residue HEM A 1001 |
| Chain | Residue |
| A | TYR78 |
| A | ALA608 |
| A | GLY612 |
| A | PHE613 |
| A | ILE615 |
| A | ASN616 |
| A | LEU621 |
| A | GLN625 |
| A | GLY626 |
| A | SER630 |
| A | HIS633 |
| A | GLU411 |
| A | ALA637 |
| A | LEU638 |
| A | TYR642 |
| A | HEM1002 |
| A | CA1003 |
| A | FE1004 |
| A | TYR412 |
| A | TRP486 |
| A | HIS490 |
| A | GLU494 |
| A | HIS542 |
| A | VAL564 |
| A | LEU567 |
| site_id | AC2 |
| Number of Residues | 24 |
| Details | binding site for residue HEM A 1002 |
| Chain | Residue |
| A | GLY76 |
| A | TYR78 |
| A | GLN294 |
| A | VAL295 |
| A | GLY298 |
| A | GLY299 |
| A | THR301 |
| A | ALA302 |
| A | ARG332 |
| A | HIS335 |
| A | ILE336 |
| A | GLU411 |
| A | TYR412 |
| A | HIS635 |
| A | LEU638 |
| A | PHE639 |
| A | MET682 |
| A | ARG721 |
| A | ARG724 |
| A | ASP728 |
| A | PHE731 |
| A | ILE732 |
| A | HEM1001 |
| A | CA1003 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 1003 |
| Chain | Residue |
| A | GLY76 |
| A | TYR78 |
| A | GLU411 |
| A | HEM1001 |
| A | HEM1002 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue FE A 1004 |
| Chain | Residue |
| A | HIS490 |
| A | HIS541 |
| A | HIS542 |
| A | HEM1001 |
Functional Information from PROSITE/UniProt
| site_id | PS00077 |
| Number of Residues | 57 |
| Details | COX1_CUB Heme-copper oxidase catalytic subunit, copper B binding region signature. WWVVHLwVegffevfataafafvfynmgfvrrstatastlaaaaifmlggvpgtlHH |
| Chain | Residue | Details |
| A | TRP486-HIS542 | |
