6FVO
Mutant DNA polymerase sliding clamp from Mycobacterium tuberculosis with bound P7 peptide
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003677 | molecular_function | DNA binding |
A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
A | 0005576 | cellular_component | extracellular region |
A | 0005737 | cellular_component | cytoplasm |
A | 0006260 | biological_process | DNA replication |
A | 0006271 | biological_process | DNA strand elongation involved in DNA replication |
A | 0008408 | molecular_function | 3'-5' exonuclease activity |
A | 0009274 | cellular_component | peptidoglycan-based cell wall |
A | 0009360 | cellular_component | DNA polymerase III complex |
A | 0042802 | molecular_function | identical protein binding |
A | 0046677 | biological_process | response to antibiotic |
A | 0071897 | biological_process | DNA biosynthetic process |
B | 0003677 | molecular_function | DNA binding |
B | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
B | 0005576 | cellular_component | extracellular region |
B | 0005737 | cellular_component | cytoplasm |
B | 0006260 | biological_process | DNA replication |
B | 0006271 | biological_process | DNA strand elongation involved in DNA replication |
B | 0008408 | molecular_function | 3'-5' exonuclease activity |
B | 0009274 | cellular_component | peptidoglycan-based cell wall |
B | 0009360 | cellular_component | DNA polymerase III complex |
B | 0042802 | molecular_function | identical protein binding |
B | 0046677 | biological_process | response to antibiotic |
B | 0071897 | biological_process | DNA biosynthetic process |
C | 0003677 | molecular_function | DNA binding |
C | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
C | 0005576 | cellular_component | extracellular region |
C | 0005737 | cellular_component | cytoplasm |
C | 0006260 | biological_process | DNA replication |
C | 0006271 | biological_process | DNA strand elongation involved in DNA replication |
C | 0008408 | molecular_function | 3'-5' exonuclease activity |
C | 0009274 | cellular_component | peptidoglycan-based cell wall |
C | 0009360 | cellular_component | DNA polymerase III complex |
C | 0042802 | molecular_function | identical protein binding |
C | 0046677 | biological_process | response to antibiotic |
C | 0071897 | biological_process | DNA biosynthetic process |
D | 0003677 | molecular_function | DNA binding |
D | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
D | 0005576 | cellular_component | extracellular region |
D | 0005737 | cellular_component | cytoplasm |
D | 0006260 | biological_process | DNA replication |
D | 0006271 | biological_process | DNA strand elongation involved in DNA replication |
D | 0008408 | molecular_function | 3'-5' exonuclease activity |
D | 0009274 | cellular_component | peptidoglycan-based cell wall |
D | 0009360 | cellular_component | DNA polymerase III complex |
D | 0042802 | molecular_function | identical protein binding |
D | 0046677 | biological_process | response to antibiotic |
D | 0071897 | biological_process | DNA biosynthetic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 2 |
Details | binding site for residue CA B 501 |
Chain | Residue |
B | LEU264 |
B | SER362 |
site_id | AC2 |
Number of Residues | 2 |
Details | binding site for residue CA C 501 |
Chain | Residue |
B | ASP125 |
C | ASP255 |
site_id | AC3 |
Number of Residues | 8 |
Details | binding site for Di-peptide ACE H 1 and GLN H 2 |
Chain | Residue |
A | ARG399 |
D | ARG293 |
H | ALC3 |
A | ASN336 |
A | TYR339 |
A | MET396 |
A | PRO397 |
A | VAL398 |
site_id | AC4 |
Number of Residues | 10 |
Details | binding site for Di-peptide GLN H 2 and ALC H 3 |
Chain | Residue |
A | ASN336 |
A | TYR339 |
A | GLY360 |
A | MET396 |
A | PRO397 |
A | VAL398 |
A | ARG399 |
D | ARG293 |
H | ACE1 |
H | ASP4 |
site_id | AC5 |
Number of Residues | 10 |
Details | binding site for Di-peptide ALC H 3 and ASP H 4 |
Chain | Residue |
A | ARG183 |
A | PHE184 |
A | GLY360 |
A | MET396 |
A | PRO397 |
A | ARG399 |
H | ACE1 |
H | GLN2 |
H | LEU5 |
H | PHE6 |
site_id | AC6 |
Number of Residues | 8 |
Details | binding site for Di-peptide ACE I 1 and GLN I 2 |
Chain | Residue |
B | PHE184 |
B | ASN336 |
B | TYR339 |
B | MET396 |
B | PRO397 |
B | VAL398 |
B | ARG399 |
I | ALC3 |
site_id | AC7 |
Number of Residues | 7 |
Details | binding site for Di-peptide GLN I 2 and ALC I 3 |
Chain | Residue |
B | PHE184 |
B | ASN336 |
B | TYR339 |
B | MET396 |
B | PRO397 |
I | ACE1 |
I | ASP4 |
site_id | AC8 |
Number of Residues | 7 |
Details | binding site for Di-peptide ALC I 3 and ASP I 4 |
Chain | Residue |
B | ARG183 |
B | PHE184 |
B | MET396 |
B | PRO397 |
I | GLN2 |
I | LEU5 |
I | PHE6 |
site_id | AC9 |
Number of Residues | 7 |
Details | binding site for Di-peptide ACE J 1 and GLN J 2 |
Chain | Residue |
B | ASP255 |
C | PHE184 |
C | MET396 |
C | PRO397 |
C | VAL398 |
C | ARG399 |
J | ALC3 |
site_id | AD1 |
Number of Residues | 6 |
Details | binding site for Di-peptide GLN J 2 and ALC J 3 |
Chain | Residue |
C | PHE184 |
C | GLY360 |
C | MET396 |
C | PRO397 |
J | ACE1 |
J | ASP4 |
site_id | AD2 |
Number of Residues | 9 |
Details | binding site for Di-peptide ALC J 3 and ASP J 4 |
Chain | Residue |
C | ARG183 |
C | PHE184 |
C | GLY360 |
C | MET396 |
C | PRO397 |
J | ACE1 |
J | GLN2 |
J | LEU5 |
J | PHE6 |
site_id | AD3 |
Number of Residues | 6 |
Details | binding site for Di-peptide ACE K 1 and GLN K 2 |
Chain | Residue |
D | PHE184 |
D | MET396 |
D | PRO397 |
D | VAL398 |
D | ARG399 |
K | ALC3 |
site_id | AD4 |
Number of Residues | 8 |
Details | binding site for Di-peptide GLN K 2 and ALC K 3 |
Chain | Residue |
D | PHE184 |
D | GLY360 |
D | MET396 |
D | PRO397 |
D | VAL398 |
D | ARG399 |
K | ACE1 |
K | ASP4 |
site_id | AD5 |
Number of Residues | 10 |
Details | binding site for Di-peptide ALC K 3 and ASP K 4 |
Chain | Residue |
K | PHE6 |
D | ARG183 |
D | PHE184 |
D | GLY360 |
D | MET396 |
D | PRO397 |
D | ARG399 |
K | ACE1 |
K | GLN2 |
K | LEU5 |