6FVO
Mutant DNA polymerase sliding clamp from Mycobacterium tuberculosis with bound P7 peptide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006260 | biological_process | DNA replication |
| A | 0006271 | biological_process | DNA strand elongation involved in DNA replication |
| A | 0008408 | molecular_function | 3'-5' exonuclease activity |
| A | 0009360 | cellular_component | DNA polymerase III complex |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0071897 | biological_process | DNA biosynthetic process |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006260 | biological_process | DNA replication |
| B | 0006271 | biological_process | DNA strand elongation involved in DNA replication |
| B | 0008408 | molecular_function | 3'-5' exonuclease activity |
| B | 0009360 | cellular_component | DNA polymerase III complex |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0071897 | biological_process | DNA biosynthetic process |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| C | 0005576 | cellular_component | extracellular region |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006260 | biological_process | DNA replication |
| C | 0006271 | biological_process | DNA strand elongation involved in DNA replication |
| C | 0008408 | molecular_function | 3'-5' exonuclease activity |
| C | 0009360 | cellular_component | DNA polymerase III complex |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0071897 | biological_process | DNA biosynthetic process |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| D | 0005576 | cellular_component | extracellular region |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006260 | biological_process | DNA replication |
| D | 0006271 | biological_process | DNA strand elongation involved in DNA replication |
| D | 0008408 | molecular_function | 3'-5' exonuclease activity |
| D | 0009360 | cellular_component | DNA polymerase III complex |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0071897 | biological_process | DNA biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | binding site for residue CA B 501 |
| Chain | Residue |
| B | LEU264 |
| B | SER362 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue CA C 501 |
| Chain | Residue |
| B | ASP125 |
| C | ASP255 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for Di-peptide ACE H 1 and GLN H 2 |
| Chain | Residue |
| A | ARG399 |
| D | ARG293 |
| H | ALC3 |
| A | ASN336 |
| A | TYR339 |
| A | MET396 |
| A | PRO397 |
| A | VAL398 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for Di-peptide GLN H 2 and ALC H 3 |
| Chain | Residue |
| A | ASN336 |
| A | TYR339 |
| A | GLY360 |
| A | MET396 |
| A | PRO397 |
| A | VAL398 |
| A | ARG399 |
| D | ARG293 |
| H | ACE1 |
| H | ASP4 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | binding site for Di-peptide ALC H 3 and ASP H 4 |
| Chain | Residue |
| A | ARG183 |
| A | PHE184 |
| A | GLY360 |
| A | MET396 |
| A | PRO397 |
| A | ARG399 |
| H | ACE1 |
| H | GLN2 |
| H | LEU5 |
| H | PHE6 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for Di-peptide ACE I 1 and GLN I 2 |
| Chain | Residue |
| B | PHE184 |
| B | ASN336 |
| B | TYR339 |
| B | MET396 |
| B | PRO397 |
| B | VAL398 |
| B | ARG399 |
| I | ALC3 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for Di-peptide GLN I 2 and ALC I 3 |
| Chain | Residue |
| B | PHE184 |
| B | ASN336 |
| B | TYR339 |
| B | MET396 |
| B | PRO397 |
| I | ACE1 |
| I | ASP4 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for Di-peptide ALC I 3 and ASP I 4 |
| Chain | Residue |
| B | ARG183 |
| B | PHE184 |
| B | MET396 |
| B | PRO397 |
| I | GLN2 |
| I | LEU5 |
| I | PHE6 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for Di-peptide ACE J 1 and GLN J 2 |
| Chain | Residue |
| B | ASP255 |
| C | PHE184 |
| C | MET396 |
| C | PRO397 |
| C | VAL398 |
| C | ARG399 |
| J | ALC3 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for Di-peptide GLN J 2 and ALC J 3 |
| Chain | Residue |
| C | PHE184 |
| C | GLY360 |
| C | MET396 |
| C | PRO397 |
| J | ACE1 |
| J | ASP4 |
| site_id | AD2 |
| Number of Residues | 9 |
| Details | binding site for Di-peptide ALC J 3 and ASP J 4 |
| Chain | Residue |
| C | ARG183 |
| C | PHE184 |
| C | GLY360 |
| C | MET396 |
| C | PRO397 |
| J | ACE1 |
| J | GLN2 |
| J | LEU5 |
| J | PHE6 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for Di-peptide ACE K 1 and GLN K 2 |
| Chain | Residue |
| D | PHE184 |
| D | MET396 |
| D | PRO397 |
| D | VAL398 |
| D | ARG399 |
| K | ALC3 |
| site_id | AD4 |
| Number of Residues | 8 |
| Details | binding site for Di-peptide GLN K 2 and ALC K 3 |
| Chain | Residue |
| D | PHE184 |
| D | GLY360 |
| D | MET396 |
| D | PRO397 |
| D | VAL398 |
| D | ARG399 |
| K | ACE1 |
| K | ASP4 |
| site_id | AD5 |
| Number of Residues | 10 |
| Details | binding site for Di-peptide ALC K 3 and ASP K 4 |
| Chain | Residue |
| K | PHE6 |
| D | ARG183 |
| D | PHE184 |
| D | GLY360 |
| D | MET396 |
| D | PRO397 |
| D | ARG399 |
| K | ACE1 |
| K | GLN2 |
| K | LEU5 |
