Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0019082 | biological_process | viral protein processing |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0019082 | biological_process | viral protein processing |
| C | 0008233 | molecular_function | peptidase activity |
| C | 0019082 | biological_process | viral protein processing |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue E8E A 401 |
| Chain | Residue |
| A | VAL26 |
| A | ILE165 |
| A | GLU166 |
| A | PRO189 |
| A | HOH513 |
| A | HOH552 |
| A | HOH584 |
| A | HOH640 |
| A | HIS41 |
| A | PHE139 |
| A | ASN141 |
| A | GLY142 |
| A | ALA143 |
| A | CYS144 |
| A | HIS163 |
| A | GLN164 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 402 |
| Chain | Residue |
| A | LYS5 |
| A | MET6 |
| A | GLN8 |
| A | SER110 |
| A | PHE111 |
| A | ASN112 |
| A | GLY126 |
| A | ASN150 |
| A | GLU292 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue DMS A 403 |
| Chain | Residue |
| A | ASP202 |
| A | TYR248 |
| A | HOH578 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue DMS A 404 |
| Chain | Residue |
| A | HIS100 |
| A | HOH714 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 405 |
| Chain | Residue |
| A | ARG130 |
| A | LYS136 |
| A | HOH617 |
| A | HOH629 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | binding site for residue GOL B 402 |
| Chain | Residue |
| B | LYS5 |
| B | MET6 |
| B | GLN8 |
| B | SER110 |
| B | PHE111 |
| B | ASN112 |
| B | GLY126 |
| B | ASN150 |
| B | GLU292 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 403 |
| Chain | Residue |
| A | HOH548 |
| B | GLU166 |
| B | E8E401 |
| B | HOH556 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 404 |
| Chain | Residue |
| A | SER222 |
| A | HOH527 |
| B | ARG40 |
| B | HOH535 |
| B | HOH540 |
| B | HOH566 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 402 |
| Chain | Residue |
| B | TYR117 |
| B | SER122 |
| C | LYS295 |
| C | GLY299 |
| C | HOH574 |
| site_id | AD1 |
| Number of Residues | 9 |
| Details | binding site for Ligand LEU B 269 bound to SER B 265 |
| Chain | Residue |
| B | TRP219 |
| B | SER265 |
| B | ILE266 |
| B | GLN267 |
| B | HIS268 |
| B | HIS270 |
| B | GLU271 |
| B | GLY272 |
| B | PHE273 |
| site_id | AD2 |
| Number of Residues | 22 |
| Details | binding site for Di-peptide E8E B 401 and CYS B 144 |
| Chain | Residue |
| A | ASN153 |
| B | VAL26 |
| B | LEU27 |
| B | ASN28 |
| B | HIS41 |
| B | PHE139 |
| B | ASN141 |
| B | GLY142 |
| B | ALA143 |
| B | GLY145 |
| B | SER146 |
| B | HIS163 |
| B | GLN164 |
| B | ILE165 |
| B | GLU166 |
| B | ASP187 |
| B | GLN188 |
| B | PRO189 |
| B | GOL403 |
| B | HOH510 |
| B | HOH513 |
| B | HOH578 |
| site_id | AD3 |
| Number of Residues | 19 |
| Details | binding site for Di-peptide E8E C 401 and CYS C 144 |
| Chain | Residue |
| C | HIS163 |
| C | GLN164 |
| C | ILE165 |
| C | GLU166 |
| C | GLY168 |
| C | ASP187 |
| C | SER190 |
| C | LEU191 |
| C | HOH571 |
| C | VAL26 |
| C | LEU27 |
| C | ASN28 |
| C | HIS41 |
| C | PHE139 |
| C | ASN141 |
| C | GLY142 |
| C | ALA143 |
| C | GLY145 |
| C | SER146 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Active site: {"description":"For 3CL-PRO activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU00772","evidenceCode":"ECO:0000255"}]} |
