6FUX

Structure of aminoglycoside phosphotransferase APH(3'')-Id from Streptomyces rimosus ATCC10970 in complex with ADP and streptomycin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0016773	molecular_function	phosphotransferase activity, alcohol group as acceptor
A	0046677	biological_process	response to antibiotic

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue GOL A 301

Chain	Residue
A	LYS43
A	GLU56
A	VAL60
A	ILE208
A	ASP209
A	LEU210
A	ADP302
A	HOH525

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site_id	AC2
Number of Residues	12
Details	binding site for residue ADP A 302

Chain	Residue
A	PRO71
A	THR87
A	SER88
A	THR89
A	VAL90
A	ILE208
A	ASP209
A	GOL301
A	HOH404
A	HOH413
A	HOH420
A	TYR41

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site_id	AC3
Number of Residues	19
Details	binding site for residue SRY A 303

Chain	Residue
A	ASP150
A	PHE151
A	LEU152
A	ARG157
A	ASP189
A	CYS191
A	PRO193
A	GLU231
A	ASP267
A	PRO268
A	TRP271
A	HOH425
A	HOH431
A	HOH457
A	HOH459
A	HOH487
A	HOH526
A	HOH546
A	HOH554

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