Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 301 |
| Chain | Residue |
| A | ILE114 |
| A | ASN116 |
| A | PHE169 |
| A | LYS170 |
| A | SER171 |
| A | EDO302 |
| A | HOH455 |
| A | HOH467 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | EDO301 |
| A | ASN116 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | HIS10 |
| A | HOH423 |
| C | ASN191 |
| C | ILE193 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 304 |
| Chain | Residue |
| A | SER12 |
| A | SER14 |
| A | HOH408 |
| A | HOH429 |
| A | HOH520 |
| C | PRO195 |
| C | ASP197 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 305 |
| Chain | Residue |
| A | LYS132 |
| A | SER133 |
| A | SER178 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 301 |
| Chain | Residue |
| B | TRP156 |
| B | LYS160 |
| B | GLU161 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 302 |
| Chain | Residue |
| B | MET19 |
| B | SER64 |
| B | VAL65 |
| B | SER66 |
| B | SER74 |
| B | SER76 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 303 |
| Chain | Residue |
| B | GLU161 |
| B | VAL162 |
| B | HIS163 |
| B | SER164 |
| B | GOL308 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 304 |
| Chain | Residue |
| B | GLY159 |
| B | HIS203 |
| B | ARG205 |
| B | HOH418 |
| B | HOH438 |
| B | HOH515 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 305 |
| Chain | Residue |
| B | LEU113 |
| B | ASN114 |
| B | GLU218 |
| B | TRP219 |
| B | HOH403 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 306 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 307 |
| Chain | Residue |
| B | ARG10 |
| B | ILE11 |
| B | GLY212 |
| B | LEU213 |
| B | SER214 |
| B | THR228 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 308 |
| Chain | Residue |
| B | VAL162 |
| B | PHE196 |
| B | SO4303 |
| B | HOH423 |
| B | HOH464 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 301 |
| Chain | Residue |
| C | HIS109 |
| C | ASP158 |
| C | LYS159 |
| C | GOL307 |
| C | HOH488 |
| C | HOH523 |
| site_id | AD6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 302 |
| Chain | Residue |
| C | ARG107 |
| C | HIS109 |
| C | GOL307 |
| C | HOH407 |
| D | PRO170 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 303 |
| Chain | Residue |
| C | PHE169 |
| C | LYS170 |
| C | HOH449 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 304 |
| Chain | Residue |
| C | LYS68 |
| C | LYS69 |
| C | SER70 |
| C | HOH411 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue GOL C 305 |
| Chain | Residue |
| C | GLU15 |
| C | HIS82 |
| C | MET83 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue GOL C 306 |
| Chain | Residue |
| C | LYS132 |
| C | SER133 |
| C | SER178 |
| site_id | AE2 |
| Number of Residues | 10 |
| Details | binding site for residue GOL C 307 |
| Chain | Residue |
| C | MET83 |
| C | ALA86 |
| C | HIS109 |
| C | ILE110 |
| C | VAL161 |
| C | EDO301 |
| C | EDO302 |
| C | HOH402 |
| C | HOH468 |
| C | HOH472 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 301 |
| Chain | Residue |
| D | EDO306 |
| D | HOH469 |
| D | ARG35 |
| D | ARG43 |
| D | ASN83 |
| site_id | AE4 |
| Number of Residues | 2 |
| Details | binding site for residue EDO D 302 |
| Chain | Residue |
| D | EDO303 |
| D | EDO305 |
| site_id | AE5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 303 |
| Chain | Residue |
| D | TYR46 |
| D | LYS56 |
| D | SER60 |
| D | ASP61 |
| D | TYR63 |
| D | EDO302 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 304 |
| Chain | Residue |
| D | ASN114 |
| D | GLU218 |
| D | TRP219 |
| D | THR220 |
| site_id | AE7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 305 |
| Chain | Residue |
| D | TYR46 |
| D | LYS56 |
| D | EDO302 |
| D | HOH427 |
| site_id | AE8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO D 306 |
| Chain | Residue |
| D | ARG35 |
| D | ASP61 |
| D | TYR63 |
| D | ASN83 |
| D | GLN84 |
| D | EDO301 |
| D | EDO307 |
| site_id | AE9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 307 |
| Chain | Residue |
| D | SER79 |
| D | ILE81 |
| D | EDO306 |
| D | HOH444 |
| site_id | AF1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 308 |
| Chain | Residue |
| D | VAL3 |
| D | THR4 |
| D | GLN5 |
| D | GLY102 |
| D | SER103 |
| site_id | AF2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO D 309 |
| Chain | Residue |
| D | HIS203 |
| D | ARG205 |
| D | HOH438 |
| site_id | AF3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 310 |
| Chain | Residue |
| D | PRO148 |
| D | ASP149 |
| D | TYR184 |
| D | HOH404 |
| site_id | AF4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 D 311 |
| Chain | Residue |
| D | PRO7 |
| D | ARG8 |
| D | ASN9 |
| D | HOH446 |
| site_id | AF5 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 D 312 |
| Chain | Residue |
| C | ASP97 |
| C | ASP98 |
| D | ARG30 |
| D | TYR32 |
| D | SER93 |
| D | ASP94 |
| D | GLU95 |
| D | SER96 |
| D | TYR97 |
| site_id | AF6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 D 313 |
| Chain | Residue |
| D | THR85 |
| D | ALA86 |
| D | ARG106 |
| D | LEU107 |
| site_id | AF7 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 D 314 |
| Chain | Residue |
| D | ASN9 |
| D | ARG10 |
| D | ILE11 |
| D | ARG106 |
| D | THR108 |
| D | HIS150 |
| D | TYR211 |
| site_id | AF8 |
| Number of Residues | 6 |
| Details | binding site for residue GOL D 315 |
| Chain | Residue |
| C | ARG165 |
| D | VAL162 |
| D | HIS163 |
| D | SER164 |
| D | HOH451 |
| D | HOH506 |
| site_id | AF9 |
| Number of Residues | 7 |
| Details | binding site for residue GOL D 316 |
| Chain | Residue |
| D | ILE11 |
| D | THR12 |
| D | LYS13 |
| D | LYS16 |
| D | LEU113 |
| D | ASP217 |
| D | HOH540 |
