Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 301 |
| Chain | Residue |
| A | MET167 |
| A | HOH405 |
| A | HOH416 |
| B | GLN221 |
| B | ARG223 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | SER70 |
| A | HOH460 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue EDO A 303 |
| Chain | Residue |
| A | SER80 |
| A | ALA81 |
| A | HIS82 |
| A | HOH404 |
| A | HOH437 |
| B | GLU111 |
| B | ASP112 |
| A | GLU15 |
| A | GLY16 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 304 |
| Chain | Residue |
| A | TYR39 |
| A | LYS78 |
| A | SER84 |
| A | ASP85 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 305 |
| Chain | Residue |
| A | LEU111 |
| A | PRO112 |
| A | ILE114 |
| A | SER142 |
| A | LYS159 |
| A | ASN172 |
| A | EDO310 |
| A | HOH477 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 306 |
| Chain | Residue |
| A | VAL121 |
| A | CYS185 |
| A | PHE200 |
| A | PRO201 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 307 |
| Chain | Residue |
| A | GLU95 |
| A | GLN96 |
| A | ASP97 |
| A | HOH436 |
| A | HOH488 |
| B | TYR97 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | binding site for residue EDO A 308 |
| Chain | Residue |
| A | ALA86 |
| A | ALA87 |
| A | ARG107 |
| A | LEU108 |
| A | HIS109 |
| A | PEG313 |
| A | HOH418 |
| A | HOH454 |
| A | HOH506 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 309 |
| Chain | Residue |
| A | PRO79 |
| A | HOH433 |
| A | HOH537 |
| B | PRO82 |
| B | HOH437 |
| B | HOH546 |
| site_id | AD1 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 310 |
| Chain | Residue |
| A | SER14 |
| A | LEU111 |
| A | PRO112 |
| A | ASN113 |
| A | SER142 |
| A | GLN143 |
| A | EDO305 |
| A | HOH446 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 311 |
| Chain | Residue |
| A | GLN6 |
| A | GLY8 |
| A | SER9 |
| A | LYS104 |
| A | GLY105 |
| A | ASN187 |
| A | ASN190 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 312 |
| Chain | Residue |
| A | ARG22 |
| A | ASP197 |
| A | PHE199 |
| A | HOH403 |
| A | HOH430 |
| site_id | AD4 |
| Number of Residues | 11 |
| Details | binding site for residue PEG A 313 |
| Chain | Residue |
| A | HIS109 |
| A | LYS159 |
| A | VAL161 |
| A | ILE193 |
| A | EDO308 |
| A | SO4316 |
| A | HOH458 |
| A | HOH471 |
| A | HOH494 |
| A | HOH515 |
| A | HOH557 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue PEG A 314 |
| Chain | Residue |
| A | GLN115 |
| A | ASN116 |
| A | PHE169 |
| A | LYS170 |
| A | HOH432 |
| A | HOH466 |
| site_id | AD6 |
| Number of Residues | 8 |
| Details | binding site for residue PEG A 315 |
| Chain | Residue |
| A | GLU64 |
| A | ALA65 |
| A | GLU66 |
| A | LYS68 |
| A | HIS75 |
| A | THR77 |
| A | HOH428 |
| A | HOH447 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 316 |
| Chain | Residue |
| A | ASN191 |
| A | ILE193 |
| A | PEG313 |
| A | HIS10 |
| site_id | AD8 |
| Number of Residues | 9 |
| Details | binding site for residue EDO B 301 |
| Chain | Residue |
| B | ARG17 |
| B | MET19 |
| B | SER64 |
| B | VAL65 |
| B | SER66 |
| B | SER74 |
| B | SER76 |
| B | GLU234 |
| B | TRP236 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 302 |
| Chain | Residue |
| B | VAL3 |
| B | THR4 |
| B | GLN5 |
| B | GLY102 |
| B | SER103 |
| B | HOH467 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 303 |
| Chain | Residue |
| B | ASN114 |
| B | GLU218 |
| B | TRP219 |
| B | THR220 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 304 |
| Chain | Residue |
| B | ARG35 |
| B | ASP61 |
| B | TYR63 |
| B | ASN83 |
| B | GLN84 |
| B | EDO307 |
| site_id | AE3 |
| Number of Residues | 9 |
| Details | binding site for residue EDO B 305 |
| Chain | Residue |
| A | ASP97 |
| A | ASP98 |
| B | ARG30 |
| B | SER93 |
| B | ASP94 |
| B | GLU95 |
| B | SER96 |
| B | TYR97 |
| B | HOH516 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 306 |
| Chain | Residue |
| B | TRP156 |
| B | LYS160 |
| B | GLU161 |
| B | HOH479 |
| site_id | AE5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 307 |
| Chain | Residue |
| B | ARG35 |
| B | ARG43 |
| B | ASN83 |
| B | EDO304 |
| B | HOH540 |
| site_id | AE6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 308 |
| Chain | Residue |
| B | VAL151 |
| B | ASP169 |
| B | PRO170 |
| B | LEU186 |
| B | HOH410 |
| B | HOH520 |
| B | HOH528 |
| site_id | AE7 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 309 |
| Chain | Residue |
| B | ALA1 |
| B | ASP2 |
| B | THR4 |
| B | SER23 |
| B | GLN24 |
| B | THR25 |
| B | HOH440 |
| B | HOH470 |
| site_id | AE8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 310 |
| Chain | Residue |
| B | GLY57 |
| B | GLU58 |
| B | ILE59 |
| B | SER60 |
| B | ASP61 |
| site_id | AE9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 311 |
| Chain | Residue |
| B | ARG17 |
| B | PRO200 |
| B | TRP236 |
| B | GLY237 |
| B | ARG238 |
| site_id | AF1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 312 |
| Chain | Residue |
| B | TYR46 |
| B | LYS56 |
| B | SER60 |
| B | ASP61 |
| B | TYR63 |
| B | HOH451 |
| site_id | AF2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 313 |
| Chain | Residue |
| B | VAL162 |
| B | HIS163 |
| B | SER164 |
| B | HOH443 |
| B | HOH462 |
| site_id | AF3 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 B 314 |
| Chain | Residue |
| B | THR85 |
| B | ALA86 |
| B | ARG106 |
| B | LEU107 |
| B | THR108 |
| B | HOH405 |
| B | HOH415 |
| B | HOH477 |
