6FPZ
Inter-alpha-inhibitor heavy chain 1, D298A
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 701 |
| Chain | Residue |
| A | ARG65 |
| A | ARG264 |
| A | LYS266 |
| A | ILE267 |
| A | ASP269 |
| A | PHE280 |
| A | PHE281 |
| A | ALA282 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 702 |
| Chain | Residue |
| A | ASP321 |
| A | GLN469 |
| A | LYS317 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 703 |
| Chain | Residue |
| A | GLU563 |
| A | ASP599 |
| A | TYR600 |
| A | HOH956 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 704 |
| Chain | Residue |
| A | ARG612 |
| A | GLY613 |
| A | MET614 |
| A | LYS621 |
| A | SER646 |
| A | LEU648 |
| A | GLN649 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 705 |
| Chain | Residue |
| A | SER73 |
| A | ALA86 |
| A | PHE87 |
| A | ASP88 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 701 |
| Chain | Residue |
| B | ARG65 |
| B | ARG264 |
| B | ILE267 |
| B | ASP269 |
| B | PHE280 |
| B | ALA282 |
| B | PRO283 |
| B | HOH847 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 702 |
| Chain | Residue |
| B | LEU56 |
| B | SER73 |
| B | ALA86 |
| B | ASP88 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 703 |
| Chain | Residue |
| B | GLU563 |
| B | ASP599 |
| B | TYR600 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 704 |
| Chain | Residue |
| B | LYS169 |
| B | TYR175 |
| B | GLU176 |
| B | HOH816 |
| B | HOH855 |
| B | HOH857 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue ACT B 705 |
| Chain | Residue |
| B | ILE53 |
| B | VAL85 |
| B | ALA86 |
| B | GLN185 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 320 |
| Details | Domain: {"description":"VWFA","evidences":[{"source":"PROSITE-ProRule","id":"PRU00219","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Motif: {"description":"Phagocytosis uptake signal","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"S-linked (Hex...) cysteine","evidences":[{"source":"PubMed","id":"9425062","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) (complex) asparagine","featureId":"CAR_000138","evidences":[{"source":"PubMed","id":"12754519","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19139490","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9425062","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9677337","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) (complex) asparagine","featureId":"CAR_000139","evidences":[{"source":"PubMed","id":"14760718","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9425062","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9677337","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
