Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6FOI

Human Cys57/156Ala superoxide dismutase-1 (SOD1), as isolated.

Functional Information from GO Data
ChainGOidnamespacecontents
A0000302biological_processresponse to reactive oxygen species
A0000303biological_processresponse to superoxide
A0001541biological_processovarian follicle development
A0001819biological_processpositive regulation of cytokine production
A0001890biological_processplacenta development
A0001895biological_processretina homeostasis
A0002262biological_processmyeloid cell homeostasis
A0004784molecular_functionsuperoxide dismutase activity
A0005507molecular_functioncopper ion binding
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005758cellular_componentmitochondrial intermembrane space
A0005759cellular_componentmitochondrial matrix
A0005777cellular_componentperoxisome
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006749biological_processglutathione metabolic process
A0006801biological_processsuperoxide metabolic process
A0006879biological_processintracellular iron ion homeostasis
A0006915biological_processapoptotic process
A0006979biological_processresponse to oxidative stress
A0007283biological_processspermatogenesis
A0007566biological_processembryo implantation
A0007605biological_processsensory perception of sound
A0007626biological_processlocomotory behavior
A0008089biological_processanterograde axonal transport
A0008090biological_processretrograde axonal transport
A0008217biological_processregulation of blood pressure
A0008270molecular_functionzinc ion binding
A0008340biological_processdetermination of adult lifespan
A0009408biological_processresponse to heat
A0009410biological_processresponse to xenobiotic stimulus
A0010033biological_processresponse to organic substance
A0010467biological_processgene expression
A0016209molecular_functionantioxidant activity
A0016491molecular_functionoxidoreductase activity
A0019226biological_processtransmission of nerve impulse
A0019228biological_processneuronal action potential
A0019430biological_processremoval of superoxide radicals
A0030346molecular_functionprotein phosphatase 2B binding
A0031267molecular_functionsmall GTPase binding
A0031410cellular_componentcytoplasmic vesicle
A0032287biological_processperipheral nervous system myelin maintenance
A0032839cellular_componentdendrite cytoplasm
A0032930biological_processpositive regulation of superoxide anion generation
A0032991cellular_componentprotein-containing complex
A0033081biological_processregulation of T cell differentiation in thymus
A0035234biological_processectopic germ cell programmed cell death
A0040014biological_processregulation of multicellular organism growth
A0042542biological_processresponse to hydrogen peroxide
A0042554biological_processsuperoxide anion generation
A0042802molecular_functionidentical protein binding
A0043025cellular_componentneuronal cell body
A0043065biological_processpositive regulation of apoptotic process
A0043066biological_processnegative regulation of apoptotic process
A0043085biological_processpositive regulation of catalytic activity
A0043087biological_processregulation of GTPase activity
A0043410biological_processpositive regulation of MAPK cascade
A0043524biological_processnegative regulation of neuron apoptotic process
A0045471biological_processresponse to ethanol
A0045541biological_processnegative regulation of cholesterol biosynthetic process
A0045859biological_processregulation of protein kinase activity
A0046620biological_processregulation of organ growth
A0046716biological_processmuscle cell cellular homeostasis
A0046872molecular_functionmetal ion binding
A0048538biological_processthymus development
A0048678biological_processresponse to axon injury
A0050665biological_processhydrogen peroxide biosynthetic process
A0050728biological_processnegative regulation of inflammatory response
A0050766biological_processpositive regulation of phagocytosis
A0051087molecular_functionprotein-folding chaperone binding
A0051093biological_processnegative regulation of developmental process
A0051881biological_processregulation of mitochondrial membrane potential
A0060047biological_processheart contraction
A0060052biological_processneurofilament cytoskeleton organization
A0060087biological_processrelaxation of vascular associated smooth muscle
A0060088biological_processauditory receptor cell stereocilium organization
A0070062cellular_componentextracellular exosome
A0072593biological_processreactive oxygen species metabolic process
A0099610biological_processaction potential initiation
A1902177biological_processpositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
A1904115cellular_componentaxon cytoplasm
A2000242biological_processnegative regulation of reproductive process
D0000302biological_processresponse to reactive oxygen species
D0000303biological_processresponse to superoxide
D0001541biological_processovarian follicle development
D0001819biological_processpositive regulation of cytokine production
D0001890biological_processplacenta development
D0001895biological_processretina homeostasis
D0002262biological_processmyeloid cell homeostasis
D0004784molecular_functionsuperoxide dismutase activity
D0005507molecular_functioncopper ion binding
D0005515molecular_functionprotein binding
D0005576cellular_componentextracellular region
D0005615cellular_componentextracellular space
D0005634cellular_componentnucleus
D0005654cellular_componentnucleoplasm
D0005737cellular_componentcytoplasm
D0005739cellular_componentmitochondrion
D0005758cellular_componentmitochondrial intermembrane space
D0005759cellular_componentmitochondrial matrix
D0005777cellular_componentperoxisome
D0005829cellular_componentcytosol
D0005886cellular_componentplasma membrane
D0006749biological_processglutathione metabolic process
D0006801biological_processsuperoxide metabolic process
D0006879biological_processintracellular iron ion homeostasis
D0006915biological_processapoptotic process
D0006979biological_processresponse to oxidative stress
D0007283biological_processspermatogenesis
D0007566biological_processembryo implantation
D0007605biological_processsensory perception of sound
D0007626biological_processlocomotory behavior
D0008089biological_processanterograde axonal transport
D0008090biological_processretrograde axonal transport
D0008217biological_processregulation of blood pressure
D0008270molecular_functionzinc ion binding
D0008340biological_processdetermination of adult lifespan
D0009408biological_processresponse to heat
D0009410biological_processresponse to xenobiotic stimulus
D0010033biological_processresponse to organic substance
D0010467biological_processgene expression
D0016209molecular_functionantioxidant activity
D0016491molecular_functionoxidoreductase activity
D0019226biological_processtransmission of nerve impulse
D0019228biological_processneuronal action potential
D0019430biological_processremoval of superoxide radicals
D0030346molecular_functionprotein phosphatase 2B binding
D0031267molecular_functionsmall GTPase binding
D0031410cellular_componentcytoplasmic vesicle
D0032287biological_processperipheral nervous system myelin maintenance
D0032839cellular_componentdendrite cytoplasm
D0032930biological_processpositive regulation of superoxide anion generation
D0032991cellular_componentprotein-containing complex
D0033081biological_processregulation of T cell differentiation in thymus
D0035234biological_processectopic germ cell programmed cell death
D0040014biological_processregulation of multicellular organism growth
D0042542biological_processresponse to hydrogen peroxide
D0042554biological_processsuperoxide anion generation
D0042802molecular_functionidentical protein binding
D0043025cellular_componentneuronal cell body
D0043065biological_processpositive regulation of apoptotic process
D0043066biological_processnegative regulation of apoptotic process
D0043085biological_processpositive regulation of catalytic activity
D0043087biological_processregulation of GTPase activity
D0043410biological_processpositive regulation of MAPK cascade
D0043524biological_processnegative regulation of neuron apoptotic process
D0045471biological_processresponse to ethanol
D0045541biological_processnegative regulation of cholesterol biosynthetic process
D0045859biological_processregulation of protein kinase activity
D0046620biological_processregulation of organ growth
D0046716biological_processmuscle cell cellular homeostasis
D0046872molecular_functionmetal ion binding
D0048538biological_processthymus development
D0048678biological_processresponse to axon injury
D0050665biological_processhydrogen peroxide biosynthetic process
D0050728biological_processnegative regulation of inflammatory response
D0050766biological_processpositive regulation of phagocytosis
D0051087molecular_functionprotein-folding chaperone binding
D0051093biological_processnegative regulation of developmental process
D0051881biological_processregulation of mitochondrial membrane potential
D0060047biological_processheart contraction
D0060052biological_processneurofilament cytoskeleton organization
D0060087biological_processrelaxation of vascular associated smooth muscle
D0060088biological_processauditory receptor cell stereocilium organization
D0070062cellular_componentextracellular exosome
D0072593biological_processreactive oxygen species metabolic process
D0099610biological_processaction potential initiation
D1902177biological_processpositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
D1904115cellular_componentaxon cytoplasm
D2000242biological_processnegative regulation of reproductive process
F0000302biological_processresponse to reactive oxygen species
F0000303biological_processresponse to superoxide
F0001541biological_processovarian follicle development
F0001819biological_processpositive regulation of cytokine production
F0001890biological_processplacenta development
F0001895biological_processretina homeostasis
F0002262biological_processmyeloid cell homeostasis
F0004784molecular_functionsuperoxide dismutase activity
F0005507molecular_functioncopper ion binding
F0005515molecular_functionprotein binding
F0005576cellular_componentextracellular region
F0005615cellular_componentextracellular space
F0005634cellular_componentnucleus
F0005654cellular_componentnucleoplasm
F0005737cellular_componentcytoplasm
F0005739cellular_componentmitochondrion
F0005758cellular_componentmitochondrial intermembrane space
F0005759cellular_componentmitochondrial matrix
F0005777cellular_componentperoxisome
F0005829cellular_componentcytosol
F0005886cellular_componentplasma membrane
F0006749biological_processglutathione metabolic process
F0006801biological_processsuperoxide metabolic process
F0006879biological_processintracellular iron ion homeostasis
F0006915biological_processapoptotic process
F0006979biological_processresponse to oxidative stress
F0007283biological_processspermatogenesis
F0007566biological_processembryo implantation
F0007605biological_processsensory perception of sound
F0007626biological_processlocomotory behavior
F0008089biological_processanterograde axonal transport
F0008090biological_processretrograde axonal transport
F0008217biological_processregulation of blood pressure
F0008270molecular_functionzinc ion binding
F0008340biological_processdetermination of adult lifespan
F0009408biological_processresponse to heat
F0009410biological_processresponse to xenobiotic stimulus
F0010033biological_processresponse to organic substance
F0010467biological_processgene expression
F0016209molecular_functionantioxidant activity
F0016491molecular_functionoxidoreductase activity
F0019226biological_processtransmission of nerve impulse
F0019228biological_processneuronal action potential
F0019430biological_processremoval of superoxide radicals
F0030346molecular_functionprotein phosphatase 2B binding
F0031267molecular_functionsmall GTPase binding
F0031410cellular_componentcytoplasmic vesicle
F0032287biological_processperipheral nervous system myelin maintenance
F0032839cellular_componentdendrite cytoplasm
F0032930biological_processpositive regulation of superoxide anion generation
F0032991cellular_componentprotein-containing complex
F0033081biological_processregulation of T cell differentiation in thymus
F0035234biological_processectopic germ cell programmed cell death
F0040014biological_processregulation of multicellular organism growth
F0042542biological_processresponse to hydrogen peroxide
F0042554biological_processsuperoxide anion generation
F0042802molecular_functionidentical protein binding
F0043025cellular_componentneuronal cell body
F0043065biological_processpositive regulation of apoptotic process
F0043066biological_processnegative regulation of apoptotic process
F0043085biological_processpositive regulation of catalytic activity
F0043087biological_processregulation of GTPase activity
F0043410biological_processpositive regulation of MAPK cascade
F0043524biological_processnegative regulation of neuron apoptotic process
F0045471biological_processresponse to ethanol
F0045541biological_processnegative regulation of cholesterol biosynthetic process
F0045859biological_processregulation of protein kinase activity
F0046620biological_processregulation of organ growth
F0046716biological_processmuscle cell cellular homeostasis
F0046872molecular_functionmetal ion binding
F0048538biological_processthymus development
F0048678biological_processresponse to axon injury
F0050665biological_processhydrogen peroxide biosynthetic process
F0050728biological_processnegative regulation of inflammatory response
F0050766biological_processpositive regulation of phagocytosis
F0051087molecular_functionprotein-folding chaperone binding
F0051093biological_processnegative regulation of developmental process
F0051881biological_processregulation of mitochondrial membrane potential
F0060047biological_processheart contraction
F0060052biological_processneurofilament cytoskeleton organization
F0060087biological_processrelaxation of vascular associated smooth muscle
F0060088biological_processauditory receptor cell stereocilium organization
F0070062cellular_componentextracellular exosome
F0072593biological_processreactive oxygen species metabolic process
F0099610biological_processaction potential initiation
F1902177biological_processpositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
F1904115cellular_componentaxon cytoplasm
F2000242biological_processnegative regulation of reproductive process
G0000302biological_processresponse to reactive oxygen species
G0000303biological_processresponse to superoxide
G0001541biological_processovarian follicle development
G0001819biological_processpositive regulation of cytokine production
G0001890biological_processplacenta development
G0001895biological_processretina homeostasis
G0002262biological_processmyeloid cell homeostasis
G0004784molecular_functionsuperoxide dismutase activity
G0005507molecular_functioncopper ion binding
G0005515molecular_functionprotein binding
G0005576cellular_componentextracellular region
G0005615cellular_componentextracellular space
G0005634cellular_componentnucleus
G0005654cellular_componentnucleoplasm
G0005737cellular_componentcytoplasm
G0005739cellular_componentmitochondrion
G0005758cellular_componentmitochondrial intermembrane space
G0005759cellular_componentmitochondrial matrix
G0005777cellular_componentperoxisome
G0005829cellular_componentcytosol
G0005886cellular_componentplasma membrane
G0006749biological_processglutathione metabolic process
G0006801biological_processsuperoxide metabolic process
G0006879biological_processintracellular iron ion homeostasis
G0006915biological_processapoptotic process
G0006979biological_processresponse to oxidative stress
G0007283biological_processspermatogenesis
G0007566biological_processembryo implantation
G0007605biological_processsensory perception of sound
G0007626biological_processlocomotory behavior
G0008089biological_processanterograde axonal transport
G0008090biological_processretrograde axonal transport
G0008217biological_processregulation of blood pressure
G0008270molecular_functionzinc ion binding
G0008340biological_processdetermination of adult lifespan
G0009408biological_processresponse to heat
G0009410biological_processresponse to xenobiotic stimulus
G0010033biological_processresponse to organic substance
G0010467biological_processgene expression
G0016209molecular_functionantioxidant activity
G0016491molecular_functionoxidoreductase activity
G0019226biological_processtransmission of nerve impulse
G0019228biological_processneuronal action potential
G0019430biological_processremoval of superoxide radicals
G0030346molecular_functionprotein phosphatase 2B binding
G0031267molecular_functionsmall GTPase binding
G0031410cellular_componentcytoplasmic vesicle
G0032287biological_processperipheral nervous system myelin maintenance
G0032839cellular_componentdendrite cytoplasm
G0032930biological_processpositive regulation of superoxide anion generation
G0032991cellular_componentprotein-containing complex
G0033081biological_processregulation of T cell differentiation in thymus
G0035234biological_processectopic germ cell programmed cell death
G0040014biological_processregulation of multicellular organism growth
G0042542biological_processresponse to hydrogen peroxide
G0042554biological_processsuperoxide anion generation
G0042802molecular_functionidentical protein binding
G0043025cellular_componentneuronal cell body
G0043065biological_processpositive regulation of apoptotic process
G0043066biological_processnegative regulation of apoptotic process
G0043085biological_processpositive regulation of catalytic activity
G0043087biological_processregulation of GTPase activity
G0043410biological_processpositive regulation of MAPK cascade
G0043524biological_processnegative regulation of neuron apoptotic process
G0045471biological_processresponse to ethanol
G0045541biological_processnegative regulation of cholesterol biosynthetic process
G0045859biological_processregulation of protein kinase activity
G0046620biological_processregulation of organ growth
G0046716biological_processmuscle cell cellular homeostasis
G0046872molecular_functionmetal ion binding
G0048538biological_processthymus development
G0048678biological_processresponse to axon injury
G0050665biological_processhydrogen peroxide biosynthetic process
G0050728biological_processnegative regulation of inflammatory response
G0050766biological_processpositive regulation of phagocytosis
G0051087molecular_functionprotein-folding chaperone binding
G0051093biological_processnegative regulation of developmental process
G0051881biological_processregulation of mitochondrial membrane potential
G0060047biological_processheart contraction
G0060052biological_processneurofilament cytoskeleton organization
G0060087biological_processrelaxation of vascular associated smooth muscle
G0060088biological_processauditory receptor cell stereocilium organization
G0070062cellular_componentextracellular exosome
G0072593biological_processreactive oxygen species metabolic process
G0099610biological_processaction potential initiation
G1902177biological_processpositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
G1904115cellular_componentaxon cytoplasm
G2000242biological_processnegative regulation of reproductive process
I0000302biological_processresponse to reactive oxygen species
I0000303biological_processresponse to superoxide
I0001541biological_processovarian follicle development
I0001819biological_processpositive regulation of cytokine production
I0001890biological_processplacenta development
I0001895biological_processretina homeostasis
I0002262biological_processmyeloid cell homeostasis
I0004784molecular_functionsuperoxide dismutase activity
I0005507molecular_functioncopper ion binding
I0005515molecular_functionprotein binding
I0005576cellular_componentextracellular region
I0005615cellular_componentextracellular space
I0005634cellular_componentnucleus
I0005654cellular_componentnucleoplasm
I0005737cellular_componentcytoplasm
I0005739cellular_componentmitochondrion
I0005758cellular_componentmitochondrial intermembrane space
I0005759cellular_componentmitochondrial matrix
I0005777cellular_componentperoxisome
I0005829cellular_componentcytosol
I0005886cellular_componentplasma membrane
I0006749biological_processglutathione metabolic process
I0006801biological_processsuperoxide metabolic process
I0006879biological_processintracellular iron ion homeostasis
I0006915biological_processapoptotic process
I0006979biological_processresponse to oxidative stress
I0007283biological_processspermatogenesis
I0007566biological_processembryo implantation
I0007605biological_processsensory perception of sound
I0007626biological_processlocomotory behavior
I0008089biological_processanterograde axonal transport
I0008090biological_processretrograde axonal transport
I0008217biological_processregulation of blood pressure
I0008270molecular_functionzinc ion binding
I0008340biological_processdetermination of adult lifespan
I0009408biological_processresponse to heat
I0009410biological_processresponse to xenobiotic stimulus
I0010033biological_processresponse to organic substance
I0010467biological_processgene expression
I0016209molecular_functionantioxidant activity
I0016491molecular_functionoxidoreductase activity
I0019226biological_processtransmission of nerve impulse
I0019228biological_processneuronal action potential
I0019430biological_processremoval of superoxide radicals
I0030346molecular_functionprotein phosphatase 2B binding
I0031267molecular_functionsmall GTPase binding
I0031410cellular_componentcytoplasmic vesicle
I0032287biological_processperipheral nervous system myelin maintenance
I0032839cellular_componentdendrite cytoplasm
I0032930biological_processpositive regulation of superoxide anion generation
I0032991cellular_componentprotein-containing complex
I0033081biological_processregulation of T cell differentiation in thymus
I0035234biological_processectopic germ cell programmed cell death
I0040014biological_processregulation of multicellular organism growth
I0042542biological_processresponse to hydrogen peroxide
I0042554biological_processsuperoxide anion generation
I0042802molecular_functionidentical protein binding
I0043025cellular_componentneuronal cell body
I0043065biological_processpositive regulation of apoptotic process
I0043066biological_processnegative regulation of apoptotic process
I0043085biological_processpositive regulation of catalytic activity
I0043087biological_processregulation of GTPase activity
I0043410biological_processpositive regulation of MAPK cascade
I0043524biological_processnegative regulation of neuron apoptotic process
I0045471biological_processresponse to ethanol
I0045541biological_processnegative regulation of cholesterol biosynthetic process
I0045859biological_processregulation of protein kinase activity
I0046620biological_processregulation of organ growth
I0046716biological_processmuscle cell cellular homeostasis
I0046872molecular_functionmetal ion binding
I0048538biological_processthymus development
I0048678biological_processresponse to axon injury
I0050665biological_processhydrogen peroxide biosynthetic process
I0050728biological_processnegative regulation of inflammatory response
I0050766biological_processpositive regulation of phagocytosis
I0051087molecular_functionprotein-folding chaperone binding
I0051093biological_processnegative regulation of developmental process
I0051881biological_processregulation of mitochondrial membrane potential
I0060047biological_processheart contraction
I0060052biological_processneurofilament cytoskeleton organization
I0060087biological_processrelaxation of vascular associated smooth muscle
I0060088biological_processauditory receptor cell stereocilium organization
I0070062cellular_componentextracellular exosome
I0072593biological_processreactive oxygen species metabolic process
I0099610biological_processaction potential initiation
I1902177biological_processpositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
I1904115cellular_componentaxon cytoplasm
I2000242biological_processnegative regulation of reproductive process
K0000302biological_processresponse to reactive oxygen species
K0000303biological_processresponse to superoxide
K0001541biological_processovarian follicle development
K0001819biological_processpositive regulation of cytokine production
K0001890biological_processplacenta development
K0001895biological_processretina homeostasis
K0002262biological_processmyeloid cell homeostasis
K0004784molecular_functionsuperoxide dismutase activity
K0005507molecular_functioncopper ion binding
K0005515molecular_functionprotein binding
K0005576cellular_componentextracellular region
K0005615cellular_componentextracellular space
K0005634cellular_componentnucleus
K0005654cellular_componentnucleoplasm
K0005737cellular_componentcytoplasm
K0005739cellular_componentmitochondrion
K0005758cellular_componentmitochondrial intermembrane space
K0005759cellular_componentmitochondrial matrix
K0005777cellular_componentperoxisome
K0005829cellular_componentcytosol
K0005886cellular_componentplasma membrane
K0006749biological_processglutathione metabolic process
K0006801biological_processsuperoxide metabolic process
K0006879biological_processintracellular iron ion homeostasis
K0006915biological_processapoptotic process
K0006979biological_processresponse to oxidative stress
K0007283biological_processspermatogenesis
K0007566biological_processembryo implantation
K0007605biological_processsensory perception of sound
K0007626biological_processlocomotory behavior
K0008089biological_processanterograde axonal transport
K0008090biological_processretrograde axonal transport
K0008217biological_processregulation of blood pressure
K0008270molecular_functionzinc ion binding
K0008340biological_processdetermination of adult lifespan
K0009408biological_processresponse to heat
K0009410biological_processresponse to xenobiotic stimulus
K0010033biological_processresponse to organic substance
K0010467biological_processgene expression
K0016209molecular_functionantioxidant activity
K0016491molecular_functionoxidoreductase activity
K0019226biological_processtransmission of nerve impulse
K0019228biological_processneuronal action potential
K0019430biological_processremoval of superoxide radicals
K0030346molecular_functionprotein phosphatase 2B binding
K0031267molecular_functionsmall GTPase binding
K0031410cellular_componentcytoplasmic vesicle
K0032287biological_processperipheral nervous system myelin maintenance
K0032839cellular_componentdendrite cytoplasm
K0032930biological_processpositive regulation of superoxide anion generation
K0032991cellular_componentprotein-containing complex
K0033081biological_processregulation of T cell differentiation in thymus
K0035234biological_processectopic germ cell programmed cell death
K0040014biological_processregulation of multicellular organism growth
K0042542biological_processresponse to hydrogen peroxide
K0042554biological_processsuperoxide anion generation
K0042802molecular_functionidentical protein binding
K0043025cellular_componentneuronal cell body
K0043065biological_processpositive regulation of apoptotic process
K0043066biological_processnegative regulation of apoptotic process
K0043085biological_processpositive regulation of catalytic activity
K0043087biological_processregulation of GTPase activity
K0043410biological_processpositive regulation of MAPK cascade
K0043524biological_processnegative regulation of neuron apoptotic process
K0045471biological_processresponse to ethanol
K0045541biological_processnegative regulation of cholesterol biosynthetic process
K0045859biological_processregulation of protein kinase activity
K0046620biological_processregulation of organ growth
K0046716biological_processmuscle cell cellular homeostasis
K0046872molecular_functionmetal ion binding
K0048538biological_processthymus development
K0048678biological_processresponse to axon injury
K0050665biological_processhydrogen peroxide biosynthetic process
K0050728biological_processnegative regulation of inflammatory response
K0050766biological_processpositive regulation of phagocytosis
K0051087molecular_functionprotein-folding chaperone binding
K0051093biological_processnegative regulation of developmental process
K0051881biological_processregulation of mitochondrial membrane potential
K0060047biological_processheart contraction
K0060052biological_processneurofilament cytoskeleton organization
K0060087biological_processrelaxation of vascular associated smooth muscle
K0060088biological_processauditory receptor cell stereocilium organization
K0070062cellular_componentextracellular exosome
K0072593biological_processreactive oxygen species metabolic process
K0099610biological_processaction potential initiation
K1902177biological_processpositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
K1904115cellular_componentaxon cytoplasm
K2000242biological_processnegative regulation of reproductive process
M0000302biological_processresponse to reactive oxygen species
M0000303biological_processresponse to superoxide
M0001541biological_processovarian follicle development
M0001819biological_processpositive regulation of cytokine production
M0001890biological_processplacenta development
M0001895biological_processretina homeostasis
M0002262biological_processmyeloid cell homeostasis
M0004784molecular_functionsuperoxide dismutase activity
M0005507molecular_functioncopper ion binding
M0005515molecular_functionprotein binding
M0005576cellular_componentextracellular region
M0005615cellular_componentextracellular space
M0005634cellular_componentnucleus
M0005654cellular_componentnucleoplasm
M0005737cellular_componentcytoplasm
M0005739cellular_componentmitochondrion
M0005758cellular_componentmitochondrial intermembrane space
M0005759cellular_componentmitochondrial matrix
M0005777cellular_componentperoxisome
M0005829cellular_componentcytosol
M0005886cellular_componentplasma membrane
M0006749biological_processglutathione metabolic process
M0006801biological_processsuperoxide metabolic process
M0006879biological_processintracellular iron ion homeostasis
M0006915biological_processapoptotic process
M0006979biological_processresponse to oxidative stress
M0007283biological_processspermatogenesis
M0007566biological_processembryo implantation
M0007605biological_processsensory perception of sound
M0007626biological_processlocomotory behavior
M0008089biological_processanterograde axonal transport
M0008090biological_processretrograde axonal transport
M0008217biological_processregulation of blood pressure
M0008270molecular_functionzinc ion binding
M0008340biological_processdetermination of adult lifespan
M0009408biological_processresponse to heat
M0009410biological_processresponse to xenobiotic stimulus
M0010033biological_processresponse to organic substance
M0010467biological_processgene expression
M0016209molecular_functionantioxidant activity
M0016491molecular_functionoxidoreductase activity
M0019226biological_processtransmission of nerve impulse
M0019228biological_processneuronal action potential
M0019430biological_processremoval of superoxide radicals
M0030346molecular_functionprotein phosphatase 2B binding
M0031267molecular_functionsmall GTPase binding
M0031410cellular_componentcytoplasmic vesicle
M0032287biological_processperipheral nervous system myelin maintenance
M0032839cellular_componentdendrite cytoplasm
M0032930biological_processpositive regulation of superoxide anion generation
M0032991cellular_componentprotein-containing complex
M0033081biological_processregulation of T cell differentiation in thymus
M0035234biological_processectopic germ cell programmed cell death
M0040014biological_processregulation of multicellular organism growth
M0042542biological_processresponse to hydrogen peroxide
M0042554biological_processsuperoxide anion generation
M0042802molecular_functionidentical protein binding
M0043025cellular_componentneuronal cell body
M0043065biological_processpositive regulation of apoptotic process
M0043066biological_processnegative regulation of apoptotic process
M0043085biological_processpositive regulation of catalytic activity
M0043087biological_processregulation of GTPase activity
M0043410biological_processpositive regulation of MAPK cascade
M0043524biological_processnegative regulation of neuron apoptotic process
M0045471biological_processresponse to ethanol
M0045541biological_processnegative regulation of cholesterol biosynthetic process
M0045859biological_processregulation of protein kinase activity
M0046620biological_processregulation of organ growth
M0046716biological_processmuscle cell cellular homeostasis
M0046872molecular_functionmetal ion binding
M0048538biological_processthymus development
M0048678biological_processresponse to axon injury
M0050665biological_processhydrogen peroxide biosynthetic process
M0050728biological_processnegative regulation of inflammatory response
M0050766biological_processpositive regulation of phagocytosis
M0051087molecular_functionprotein-folding chaperone binding
M0051093biological_processnegative regulation of developmental process
M0051881biological_processregulation of mitochondrial membrane potential
M0060047biological_processheart contraction
M0060052biological_processneurofilament cytoskeleton organization
M0060087biological_processrelaxation of vascular associated smooth muscle
M0060088biological_processauditory receptor cell stereocilium organization
M0070062cellular_componentextracellular exosome
M0072593biological_processreactive oxygen species metabolic process
M0099610biological_processaction potential initiation
M1902177biological_processpositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
M1904115cellular_componentaxon cytoplasm
M2000242biological_processnegative regulation of reproductive process
O0000302biological_processresponse to reactive oxygen species
O0000303biological_processresponse to superoxide
O0001541biological_processovarian follicle development
O0001819biological_processpositive regulation of cytokine production
O0001890biological_processplacenta development
O0001895biological_processretina homeostasis
O0002262biological_processmyeloid cell homeostasis
O0004784molecular_functionsuperoxide dismutase activity
O0005507molecular_functioncopper ion binding
O0005515molecular_functionprotein binding
O0005576cellular_componentextracellular region
O0005615cellular_componentextracellular space
O0005634cellular_componentnucleus
O0005654cellular_componentnucleoplasm
O0005737cellular_componentcytoplasm
O0005739cellular_componentmitochondrion
O0005758cellular_componentmitochondrial intermembrane space
O0005759cellular_componentmitochondrial matrix
O0005777cellular_componentperoxisome
O0005829cellular_componentcytosol
O0005886cellular_componentplasma membrane
O0006749biological_processglutathione metabolic process
O0006801biological_processsuperoxide metabolic process
O0006879biological_processintracellular iron ion homeostasis
O0006915biological_processapoptotic process
O0006979biological_processresponse to oxidative stress
O0007283biological_processspermatogenesis
O0007566biological_processembryo implantation
O0007605biological_processsensory perception of sound
O0007626biological_processlocomotory behavior
O0008089biological_processanterograde axonal transport
O0008090biological_processretrograde axonal transport
O0008217biological_processregulation of blood pressure
O0008270molecular_functionzinc ion binding
O0008340biological_processdetermination of adult lifespan
O0009408biological_processresponse to heat
O0009410biological_processresponse to xenobiotic stimulus
O0010033biological_processresponse to organic substance
O0010467biological_processgene expression
O0016209molecular_functionantioxidant activity
O0016491molecular_functionoxidoreductase activity
O0019226biological_processtransmission of nerve impulse
O0019228biological_processneuronal action potential
O0019430biological_processremoval of superoxide radicals
O0030346molecular_functionprotein phosphatase 2B binding
O0031267molecular_functionsmall GTPase binding
O0031410cellular_componentcytoplasmic vesicle
O0032287biological_processperipheral nervous system myelin maintenance
O0032839cellular_componentdendrite cytoplasm
O0032930biological_processpositive regulation of superoxide anion generation
O0032991cellular_componentprotein-containing complex
O0033081biological_processregulation of T cell differentiation in thymus
O0035234biological_processectopic germ cell programmed cell death
O0040014biological_processregulation of multicellular organism growth
O0042542biological_processresponse to hydrogen peroxide
O0042554biological_processsuperoxide anion generation
O0042802molecular_functionidentical protein binding
O0043025cellular_componentneuronal cell body
O0043065biological_processpositive regulation of apoptotic process
O0043066biological_processnegative regulation of apoptotic process
O0043085biological_processpositive regulation of catalytic activity
O0043087biological_processregulation of GTPase activity
O0043410biological_processpositive regulation of MAPK cascade
O0043524biological_processnegative regulation of neuron apoptotic process
O0045471biological_processresponse to ethanol
O0045541biological_processnegative regulation of cholesterol biosynthetic process
O0045859biological_processregulation of protein kinase activity
O0046620biological_processregulation of organ growth
O0046716biological_processmuscle cell cellular homeostasis
O0046872molecular_functionmetal ion binding
O0048538biological_processthymus development
O0048678biological_processresponse to axon injury
O0050665biological_processhydrogen peroxide biosynthetic process
O0050728biological_processnegative regulation of inflammatory response
O0050766biological_processpositive regulation of phagocytosis
O0051087molecular_functionprotein-folding chaperone binding
O0051093biological_processnegative regulation of developmental process
O0051881biological_processregulation of mitochondrial membrane potential
O0060047biological_processheart contraction
O0060052biological_processneurofilament cytoskeleton organization
O0060087biological_processrelaxation of vascular associated smooth muscle
O0060088biological_processauditory receptor cell stereocilium organization
O0070062cellular_componentextracellular exosome
O0072593biological_processreactive oxygen species metabolic process
O0099610biological_processaction potential initiation
O1902177biological_processpositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
O1904115cellular_componentaxon cytoplasm
O2000242biological_processnegative regulation of reproductive process
Q0000302biological_processresponse to reactive oxygen species
Q0000303biological_processresponse to superoxide
Q0001541biological_processovarian follicle development
Q0001819biological_processpositive regulation of cytokine production
Q0001890biological_processplacenta development
Q0001895biological_processretina homeostasis
Q0002262biological_processmyeloid cell homeostasis
Q0004784molecular_functionsuperoxide dismutase activity
Q0005507molecular_functioncopper ion binding
Q0005515molecular_functionprotein binding
Q0005576cellular_componentextracellular region
Q0005615cellular_componentextracellular space
Q0005634cellular_componentnucleus
Q0005654cellular_componentnucleoplasm
Q0005737cellular_componentcytoplasm
Q0005739cellular_componentmitochondrion
Q0005758cellular_componentmitochondrial intermembrane space
Q0005759cellular_componentmitochondrial matrix
Q0005777cellular_componentperoxisome
Q0005829cellular_componentcytosol
Q0005886cellular_componentplasma membrane
Q0006749biological_processglutathione metabolic process
Q0006801biological_processsuperoxide metabolic process
Q0006879biological_processintracellular iron ion homeostasis
Q0006915biological_processapoptotic process
Q0006979biological_processresponse to oxidative stress
Q0007283biological_processspermatogenesis
Q0007566biological_processembryo implantation
Q0007605biological_processsensory perception of sound
Q0007626biological_processlocomotory behavior
Q0008089biological_processanterograde axonal transport
Q0008090biological_processretrograde axonal transport
Q0008217biological_processregulation of blood pressure
Q0008270molecular_functionzinc ion binding
Q0008340biological_processdetermination of adult lifespan
Q0009408biological_processresponse to heat
Q0009410biological_processresponse to xenobiotic stimulus
Q0010033biological_processresponse to organic substance
Q0010467biological_processgene expression
Q0016209molecular_functionantioxidant activity
Q0016491molecular_functionoxidoreductase activity
Q0019226biological_processtransmission of nerve impulse
Q0019228biological_processneuronal action potential
Q0019430biological_processremoval of superoxide radicals
Q0030346molecular_functionprotein phosphatase 2B binding
Q0031267molecular_functionsmall GTPase binding
Q0031410cellular_componentcytoplasmic vesicle
Q0032287biological_processperipheral nervous system myelin maintenance
Q0032839cellular_componentdendrite cytoplasm
Q0032930biological_processpositive regulation of superoxide anion generation
Q0032991cellular_componentprotein-containing complex
Q0033081biological_processregulation of T cell differentiation in thymus
Q0035234biological_processectopic germ cell programmed cell death
Q0040014biological_processregulation of multicellular organism growth
Q0042542biological_processresponse to hydrogen peroxide
Q0042554biological_processsuperoxide anion generation
Q0042802molecular_functionidentical protein binding
Q0043025cellular_componentneuronal cell body
Q0043065biological_processpositive regulation of apoptotic process
Q0043066biological_processnegative regulation of apoptotic process
Q0043085biological_processpositive regulation of catalytic activity
Q0043087biological_processregulation of GTPase activity
Q0043410biological_processpositive regulation of MAPK cascade
Q0043524biological_processnegative regulation of neuron apoptotic process
Q0045471biological_processresponse to ethanol
Q0045541biological_processnegative regulation of cholesterol biosynthetic process
Q0045859biological_processregulation of protein kinase activity
Q0046620biological_processregulation of organ growth
Q0046716biological_processmuscle cell cellular homeostasis
Q0046872molecular_functionmetal ion binding
Q0048538biological_processthymus development
Q0048678biological_processresponse to axon injury
Q0050665biological_processhydrogen peroxide biosynthetic process
Q0050728biological_processnegative regulation of inflammatory response
Q0050766biological_processpositive regulation of phagocytosis
Q0051087molecular_functionprotein-folding chaperone binding
Q0051093biological_processnegative regulation of developmental process
Q0051881biological_processregulation of mitochondrial membrane potential
Q0060047biological_processheart contraction
Q0060052biological_processneurofilament cytoskeleton organization
Q0060087biological_processrelaxation of vascular associated smooth muscle
Q0060088biological_processauditory receptor cell stereocilium organization
Q0070062cellular_componentextracellular exosome
Q0072593biological_processreactive oxygen species metabolic process
Q0099610biological_processaction potential initiation
Q1902177biological_processpositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
Q1904115cellular_componentaxon cytoplasm
Q2000242biological_processnegative regulation of reproductive process
S0000302biological_processresponse to reactive oxygen species
S0000303biological_processresponse to superoxide
S0001541biological_processovarian follicle development
S0001819biological_processpositive regulation of cytokine production
S0001890biological_processplacenta development
S0001895biological_processretina homeostasis
S0002262biological_processmyeloid cell homeostasis
S0004784molecular_functionsuperoxide dismutase activity
S0005507molecular_functioncopper ion binding
S0005515molecular_functionprotein binding
S0005576cellular_componentextracellular region
S0005615cellular_componentextracellular space
S0005634cellular_componentnucleus
S0005654cellular_componentnucleoplasm
S0005737cellular_componentcytoplasm
S0005739cellular_componentmitochondrion
S0005758cellular_componentmitochondrial intermembrane space
S0005759cellular_componentmitochondrial matrix
S0005777cellular_componentperoxisome
S0005829cellular_componentcytosol
S0005886cellular_componentplasma membrane
S0006749biological_processglutathione metabolic process
S0006801biological_processsuperoxide metabolic process
S0006879biological_processintracellular iron ion homeostasis
S0006915biological_processapoptotic process
S0006979biological_processresponse to oxidative stress
S0007283biological_processspermatogenesis
S0007566biological_processembryo implantation
S0007605biological_processsensory perception of sound
S0007626biological_processlocomotory behavior
S0008089biological_processanterograde axonal transport
S0008090biological_processretrograde axonal transport
S0008217biological_processregulation of blood pressure
S0008270molecular_functionzinc ion binding
S0008340biological_processdetermination of adult lifespan
S0009408biological_processresponse to heat
S0009410biological_processresponse to xenobiotic stimulus
S0010033biological_processresponse to organic substance
S0010467biological_processgene expression
S0016209molecular_functionantioxidant activity
S0016491molecular_functionoxidoreductase activity
S0019226biological_processtransmission of nerve impulse
S0019228biological_processneuronal action potential
S0019430biological_processremoval of superoxide radicals
S0030346molecular_functionprotein phosphatase 2B binding
S0031267molecular_functionsmall GTPase binding
S0031410cellular_componentcytoplasmic vesicle
S0032287biological_processperipheral nervous system myelin maintenance
S0032839cellular_componentdendrite cytoplasm
S0032930biological_processpositive regulation of superoxide anion generation
S0032991cellular_componentprotein-containing complex
S0033081biological_processregulation of T cell differentiation in thymus
S0035234biological_processectopic germ cell programmed cell death
S0040014biological_processregulation of multicellular organism growth
S0042542biological_processresponse to hydrogen peroxide
S0042554biological_processsuperoxide anion generation
S0042802molecular_functionidentical protein binding
S0043025cellular_componentneuronal cell body
S0043065biological_processpositive regulation of apoptotic process
S0043066biological_processnegative regulation of apoptotic process
S0043085biological_processpositive regulation of catalytic activity
S0043087biological_processregulation of GTPase activity
S0043410biological_processpositive regulation of MAPK cascade
S0043524biological_processnegative regulation of neuron apoptotic process
S0045471biological_processresponse to ethanol
S0045541biological_processnegative regulation of cholesterol biosynthetic process
S0045859biological_processregulation of protein kinase activity
S0046620biological_processregulation of organ growth
S0046716biological_processmuscle cell cellular homeostasis
S0046872molecular_functionmetal ion binding
S0048538biological_processthymus development
S0048678biological_processresponse to axon injury
S0050665biological_processhydrogen peroxide biosynthetic process
S0050728biological_processnegative regulation of inflammatory response
S0050766biological_processpositive regulation of phagocytosis
S0051087molecular_functionprotein-folding chaperone binding
S0051093biological_processnegative regulation of developmental process
S0051881biological_processregulation of mitochondrial membrane potential
S0060047biological_processheart contraction
S0060052biological_processneurofilament cytoskeleton organization
S0060087biological_processrelaxation of vascular associated smooth muscle
S0060088biological_processauditory receptor cell stereocilium organization
S0070062cellular_componentextracellular exosome
S0072593biological_processreactive oxygen species metabolic process
S0099610biological_processaction potential initiation
S1902177biological_processpositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
S1904115cellular_componentaxon cytoplasm
S2000242biological_processnegative regulation of reproductive process
U0000302biological_processresponse to reactive oxygen species
U0000303biological_processresponse to superoxide
U0001541biological_processovarian follicle development
U0001819biological_processpositive regulation of cytokine production
U0001890biological_processplacenta development
U0001895biological_processretina homeostasis
U0002262biological_processmyeloid cell homeostasis
U0004784molecular_functionsuperoxide dismutase activity
U0005507molecular_functioncopper ion binding
U0005515molecular_functionprotein binding
U0005576cellular_componentextracellular region
U0005615cellular_componentextracellular space
U0005634cellular_componentnucleus
U0005654cellular_componentnucleoplasm
U0005737cellular_componentcytoplasm
U0005739cellular_componentmitochondrion
U0005758cellular_componentmitochondrial intermembrane space
U0005759cellular_componentmitochondrial matrix
U0005777cellular_componentperoxisome
U0005829cellular_componentcytosol
U0005886cellular_componentplasma membrane
U0006749biological_processglutathione metabolic process
U0006801biological_processsuperoxide metabolic process
U0006879biological_processintracellular iron ion homeostasis
U0006915biological_processapoptotic process
U0006979biological_processresponse to oxidative stress
U0007283biological_processspermatogenesis
U0007566biological_processembryo implantation
U0007605biological_processsensory perception of sound
U0007626biological_processlocomotory behavior
U0008089biological_processanterograde axonal transport
U0008090biological_processretrograde axonal transport
U0008217biological_processregulation of blood pressure
U0008270molecular_functionzinc ion binding
U0008340biological_processdetermination of adult lifespan
U0009408biological_processresponse to heat
U0009410biological_processresponse to xenobiotic stimulus
U0010033biological_processresponse to organic substance
U0010467biological_processgene expression
U0016209molecular_functionantioxidant activity
U0016491molecular_functionoxidoreductase activity
U0019226biological_processtransmission of nerve impulse
U0019228biological_processneuronal action potential
U0019430biological_processremoval of superoxide radicals
U0030346molecular_functionprotein phosphatase 2B binding
U0031267molecular_functionsmall GTPase binding
U0031410cellular_componentcytoplasmic vesicle
U0032287biological_processperipheral nervous system myelin maintenance
U0032839cellular_componentdendrite cytoplasm
U0032930biological_processpositive regulation of superoxide anion generation
U0032991cellular_componentprotein-containing complex
U0033081biological_processregulation of T cell differentiation in thymus
U0035234biological_processectopic germ cell programmed cell death
U0040014biological_processregulation of multicellular organism growth
U0042542biological_processresponse to hydrogen peroxide
U0042554biological_processsuperoxide anion generation
U0042802molecular_functionidentical protein binding
U0043025cellular_componentneuronal cell body
U0043065biological_processpositive regulation of apoptotic process
U0043066biological_processnegative regulation of apoptotic process
U0043085biological_processpositive regulation of catalytic activity
U0043087biological_processregulation of GTPase activity
U0043410biological_processpositive regulation of MAPK cascade
U0043524biological_processnegative regulation of neuron apoptotic process
U0045471biological_processresponse to ethanol
U0045541biological_processnegative regulation of cholesterol biosynthetic process
U0045859biological_processregulation of protein kinase activity
U0046620biological_processregulation of organ growth
U0046716biological_processmuscle cell cellular homeostasis
U0046872molecular_functionmetal ion binding
U0048538biological_processthymus development
U0048678biological_processresponse to axon injury
U0050665biological_processhydrogen peroxide biosynthetic process
U0050728biological_processnegative regulation of inflammatory response
U0050766biological_processpositive regulation of phagocytosis
U0051087molecular_functionprotein-folding chaperone binding
U0051093biological_processnegative regulation of developmental process
U0051881biological_processregulation of mitochondrial membrane potential
U0060047biological_processheart contraction
U0060052biological_processneurofilament cytoskeleton organization
U0060087biological_processrelaxation of vascular associated smooth muscle
U0060088biological_processauditory receptor cell stereocilium organization
U0070062cellular_componentextracellular exosome
U0072593biological_processreactive oxygen species metabolic process
U0099610biological_processaction potential initiation
U1902177biological_processpositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
U1904115cellular_componentaxon cytoplasm
U2000242biological_processnegative regulation of reproductive process
W0000302biological_processresponse to reactive oxygen species
W0000303biological_processresponse to superoxide
W0001541biological_processovarian follicle development
W0001819biological_processpositive regulation of cytokine production
W0001890biological_processplacenta development
W0001895biological_processretina homeostasis
W0002262biological_processmyeloid cell homeostasis
W0004784molecular_functionsuperoxide dismutase activity
W0005507molecular_functioncopper ion binding
W0005515molecular_functionprotein binding
W0005576cellular_componentextracellular region
W0005615cellular_componentextracellular space
W0005634cellular_componentnucleus
W0005654cellular_componentnucleoplasm
W0005737cellular_componentcytoplasm
W0005739cellular_componentmitochondrion
W0005758cellular_componentmitochondrial intermembrane space
W0005759cellular_componentmitochondrial matrix
W0005777cellular_componentperoxisome
W0005829cellular_componentcytosol
W0005886cellular_componentplasma membrane
W0006749biological_processglutathione metabolic process
W0006801biological_processsuperoxide metabolic process
W0006879biological_processintracellular iron ion homeostasis
W0006915biological_processapoptotic process
W0006979biological_processresponse to oxidative stress
W0007283biological_processspermatogenesis
W0007566biological_processembryo implantation
W0007605biological_processsensory perception of sound
W0007626biological_processlocomotory behavior
W0008089biological_processanterograde axonal transport
W0008090biological_processretrograde axonal transport
W0008217biological_processregulation of blood pressure
W0008270molecular_functionzinc ion binding
W0008340biological_processdetermination of adult lifespan
W0009408biological_processresponse to heat
W0009410biological_processresponse to xenobiotic stimulus
W0010033biological_processresponse to organic substance
W0010467biological_processgene expression
W0016209molecular_functionantioxidant activity
W0016491molecular_functionoxidoreductase activity
W0019226biological_processtransmission of nerve impulse
W0019228biological_processneuronal action potential
W0019430biological_processremoval of superoxide radicals
W0030346molecular_functionprotein phosphatase 2B binding
W0031267molecular_functionsmall GTPase binding
W0031410cellular_componentcytoplasmic vesicle
W0032287biological_processperipheral nervous system myelin maintenance
W0032839cellular_componentdendrite cytoplasm
W0032930biological_processpositive regulation of superoxide anion generation
W0032991cellular_componentprotein-containing complex
W0033081biological_processregulation of T cell differentiation in thymus
W0035234biological_processectopic germ cell programmed cell death
W0040014biological_processregulation of multicellular organism growth
W0042542biological_processresponse to hydrogen peroxide
W0042554biological_processsuperoxide anion generation
W0042802molecular_functionidentical protein binding
W0043025cellular_componentneuronal cell body
W0043065biological_processpositive regulation of apoptotic process
W0043066biological_processnegative regulation of apoptotic process
W0043085biological_processpositive regulation of catalytic activity
W0043087biological_processregulation of GTPase activity
W0043410biological_processpositive regulation of MAPK cascade
W0043524biological_processnegative regulation of neuron apoptotic process
W0045471biological_processresponse to ethanol
W0045541biological_processnegative regulation of cholesterol biosynthetic process
W0045859biological_processregulation of protein kinase activity
W0046620biological_processregulation of organ growth
W0046716biological_processmuscle cell cellular homeostasis
W0046872molecular_functionmetal ion binding
W0048538biological_processthymus development
W0048678biological_processresponse to axon injury
W0050665biological_processhydrogen peroxide biosynthetic process
W0050728biological_processnegative regulation of inflammatory response
W0050766biological_processpositive regulation of phagocytosis
W0051087molecular_functionprotein-folding chaperone binding
W0051093biological_processnegative regulation of developmental process
W0051881biological_processregulation of mitochondrial membrane potential
W0060047biological_processheart contraction
W0060052biological_processneurofilament cytoskeleton organization
W0060087biological_processrelaxation of vascular associated smooth muscle
W0060088biological_processauditory receptor cell stereocilium organization
W0070062cellular_componentextracellular exosome
W0072593biological_processreactive oxygen species metabolic process
W0099610biological_processaction potential initiation
W1902177biological_processpositive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
W1904115cellular_componentaxon cytoplasm
W2000242biological_processnegative regulation of reproductive process
Functional Information from PDB Data
site_idAC1
Number of Residues5
Detailsbinding site for residue ZN A 201
ChainResidue
AHIS63
AHIS71
AHIS80
AASP83
ALYS136

site_idAC2
Number of Residues7
Detailsbinding site for residue SO4 A 202
ChainResidue
AHOH308
AHOH313
AHOH340
AHIS120
ATHR137
AARG143
AHOH304

site_idAC3
Number of Residues4
Detailsbinding site for residue ZN F 201
ChainResidue
FHIS63
FHIS71
FHIS80
FASP83

site_idAC4
Number of Residues8
Detailsbinding site for residue SO4 F 202
ChainResidue
FHIS120
FTHR137
FARG143
FHOH316
FHOH332
FHOH340
FHOH349
FHOH389

site_idAC5
Number of Residues6
Detailsbinding site for residue SO4 F 203
ChainResidue
FLYS128
FHOH345
FHOH357
KLYS75
KLYS128
MLYS128

site_idAC6
Number of Residues4
Detailsbinding site for residue ZN D 201
ChainResidue
DHIS63
DHIS71
DHIS80
DASP83

site_idAC7
Number of Residues6
Detailsbinding site for residue SO4 D 202
ChainResidue
DHIS48
DHIS120
DTHR137
DARG143
DHOH306
DHOH310

site_idAC8
Number of Residues4
Detailsbinding site for residue ZN G 201
ChainResidue
GHIS63
GHIS71
GHIS80
GASP83

site_idAC9
Number of Residues3
Detailsbinding site for residue SO4 G 202
ChainResidue
GTHR137
GGLY141
GARG143

site_idAD1
Number of Residues4
Detailsbinding site for residue ZN I 201
ChainResidue
IHIS63
IHIS71
IHIS80
IASP83

site_idAD2
Number of Residues5
Detailsbinding site for residue SO4 I 202
ChainResidue
IHIS48
IHIS120
ITHR137
IARG143
IHOH315

site_idAD3
Number of Residues4
Detailsbinding site for residue ZN K 201
ChainResidue
KHIS63
KHIS71
KHIS80
KASP83

site_idAD4
Number of Residues5
Detailsbinding site for residue SO4 K 202
ChainResidue
KHIS48
KHIS120
KTHR137
KARG143
KHOH301

site_idAD5
Number of Residues4
Detailsbinding site for residue ZN M 201
ChainResidue
MHIS63
MHIS71
MHIS80
MASP83

site_idAD6
Number of Residues4
Detailsbinding site for residue SO4 M 202
ChainResidue
MHIS120
MTHR137
MGLY141
MARG143

site_idAD7
Number of Residues4
Detailsbinding site for residue ZN O 201
ChainResidue
OHIS63
OHIS71
OHIS80
OASP83

site_idAD8
Number of Residues4
Detailsbinding site for residue ZN Q 201
ChainResidue
QHIS63
QHIS71
QHIS80
QASP83

site_idAD9
Number of Residues4
Detailsbinding site for residue SO4 Q 202
ChainResidue
QTHR137
QGLY141
QARG143
QHOH355

site_idAE1
Number of Residues5
Detailsbinding site for residue SO4 Q 203
ChainResidue
GLYS128
QLYS75
QLYS128
WLYS128
WHOH330

site_idAE2
Number of Residues5
Detailsbinding site for residue ZN S 201
ChainResidue
SHIS63
SHIS71
SHIS80
SASP83
SLYS136

site_idAE3
Number of Residues4
Detailsbinding site for residue SO4 S 202
ChainResidue
SHIS48
SHIS120
STHR137
SARG143

site_idAE4
Number of Residues4
Detailsbinding site for residue ZN U 201
ChainResidue
UHIS63
UHIS71
UHIS80
UASP83

site_idAE5
Number of Residues4
Detailsbinding site for residue SO4 U 202
ChainResidue
UHIS48
UHIS120
UTHR137
UARG143

site_idAE6
Number of Residues4
Detailsbinding site for residue ZN W 201
ChainResidue
WHIS63
WHIS71
WHIS80
WASP83

site_idAE7
Number of Residues5
Detailsbinding site for residue SO4 W 202
ChainResidue
WHIS48
WHIS120
WTHR137
WGLY141
WARG143

Functional Information from PROSITE/UniProt
site_idPS00087
Number of Residues11
DetailsSOD_CU_ZN_1 Copper/Zinc superoxide dismutase signature 1. GFHVHEfGDnT
ChainResidueDetails
AGLY44-THR54

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues36
DetailsBINDING: BINDING => ECO:0000269|PubMed:12963370, ECO:0000269|PubMed:17548825
ChainResidueDetails
AHIS46
AHIS48
AHIS120
FHIS46
FHIS48
FHIS120
DHIS46
DHIS48
DHIS120
GHIS46
GHIS48
GHIS120
IHIS46
IHIS48
IHIS120
KHIS46
KHIS48
KHIS120
MHIS46
MHIS48
MHIS120
OHIS46
OHIS48
OHIS120
QHIS46
QHIS48
QHIS120
SHIS46
SHIS48
SHIS120
UHIS46
UHIS48
UHIS120
WHIS46
WHIS48
WHIS120

site_idSWS_FT_FI2
Number of Residues48
DetailsBINDING: BINDING => ECO:0000269|PubMed:20727846
ChainResidueDetails
SHIS63
SHIS71
SHIS80
SASP83
UHIS63
UHIS71
UHIS80
UASP83
WHIS63
WHIS71
WHIS80
WASP83
AASP83
FHIS63
AHIS63
AHIS71
AHIS80
FHIS71
FHIS80
FASP83
DHIS63
DHIS71
DHIS80
DASP83
GHIS63
GHIS71
GHIS80
GASP83
IHIS63
IHIS71
IHIS80
IASP83
KHIS63
KHIS71
KHIS80
KASP83
MHIS63
MHIS71
MHIS80
MASP83
OHIS63
OHIS71
OHIS80
OASP83
QHIS63
QHIS71
QHIS80
QASP83

site_idSWS_FT_FI3
Number of Residues12
DetailsMOD_RES: N-acetylalanine => ECO:0000269|PubMed:1463506, ECO:0000269|PubMed:7002610, ECO:0007744|PubMed:25944712
ChainResidueDetails
AALA1
FALA1
DALA1
GALA1
IALA1
KALA1
MALA1
OALA1
QALA1
SALA1
UALA1
WALA1

site_idSWS_FT_FI4
Number of Residues36
DetailsMOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:P08228
ChainResidueDetails
ILYS3
ILYS9
ILYS91
KLYS3
KLYS9
KLYS91
MLYS3
MLYS9
MLYS91
OLYS3
OLYS9
OLYS91
QLYS3
QLYS9
QLYS91
SLYS3
SLYS9
SLYS91
ULYS3
ULYS9
ULYS91
WLYS3
WLYS9
WLYS91
ALYS3
ALYS9
ALYS91
FLYS3
FLYS9
FLYS91
DLYS3
DLYS9
DLYS91
GLYS3
GLYS9
GLYS91

site_idSWS_FT_FI5
Number of Residues12
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:24275569
ChainResidueDetails
ASER98
FSER98
DSER98
GSER98
ISER98
KSER98
MSER98
OSER98
QSER98
SSER98
USER98
WSER98

site_idSWS_FT_FI6
Number of Residues12
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569
ChainResidueDetails
ASER102
FSER102
DSER102
GSER102
ISER102
KSER102
MSER102
OSER102
QSER102
SSER102
USER102
WSER102

site_idSWS_FT_FI7
Number of Residues12
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P07632
ChainResidueDetails
ASER105
FSER105
ISER105
KSER105
MSER105
OSER105
QSER105
SSER105
USER105
WSER105
DSER105
GSER105

site_idSWS_FT_FI8
Number of Residues12
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P08228
ChainResidueDetails
ASER107
GSER107
ISER107
KSER107
MSER107
FSER107
DSER107
OSER107
QSER107
SSER107
USER107
WSER107

site_idSWS_FT_FI9
Number of Residues12
DetailsMOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:24140062
ChainResidueDetails
ALYS122
FLYS122
GLYS122
ILYS122
KLYS122
MLYS122
OLYS122
QLYS122
SLYS122
ULYS122
WLYS122
DLYS122

site_idSWS_FT_FI10
Number of Residues12
DetailsMOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P08228
ChainResidueDetails
ALYS136
FLYS136
DLYS136
GLYS136
ILYS136
KLYS136
MLYS136
OLYS136
QLYS136
SLYS136
ULYS136
WLYS136

site_idSWS_FT_FI11
Number of Residues12
DetailsLIPID: S-palmitoyl cysteine => ECO:0000269|PubMed:22496122
ChainResidueDetails
ACYS6
FCYS6
DCYS6
GCYS6
ICYS6
KCYS6
MCYS6
OCYS6
QCYS6
SCYS6
UCYS6
WCYS6

site_idSWS_FT_FI12
Number of Residues24
DetailsCROSSLNK: 1-(tryptophan-3-yl)-tryptophan (Trp-Trp) (interchain with W-33) => ECO:0000269|PubMed:20600836
ChainResidueDetails
MTRP32
OTRP32
QTRP32
STRP32
UTRP32
WTRP32
ATRP32
FTRP32
DTRP32
GTRP32
ITRP32
KTRP32

221051

PDB entries from 2024-06-12

PDB statisticsPDBj update infoContact PDBjnumon