Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6FOC

F1-ATPase from Mycobacterium smegmatis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0005886	cellular_component	plasma membrane
A	0006754	biological_process	ATP biosynthetic process
A	0015986	biological_process	proton motive force-driven ATP synthesis
A	0032559	molecular_function	adenyl ribonucleotide binding
A	0043531	molecular_function	ADP binding
A	0045259	cellular_component	proton-transporting ATP synthase complex
A	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
A	0046034	biological_process	ATP metabolic process
A	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
A	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
A	1902600	biological_process	proton transmembrane transport
B	0005524	molecular_function	ATP binding
B	0005886	cellular_component	plasma membrane
B	0006754	biological_process	ATP biosynthetic process
B	0015986	biological_process	proton motive force-driven ATP synthesis
B	0032559	molecular_function	adenyl ribonucleotide binding
B	0043531	molecular_function	ADP binding
B	0045259	cellular_component	proton-transporting ATP synthase complex
B	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
B	0046034	biological_process	ATP metabolic process
B	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
B	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
B	1902600	biological_process	proton transmembrane transport
C	0005524	molecular_function	ATP binding
C	0005886	cellular_component	plasma membrane
C	0006754	biological_process	ATP biosynthetic process
C	0015986	biological_process	proton motive force-driven ATP synthesis
C	0032559	molecular_function	adenyl ribonucleotide binding
C	0043531	molecular_function	ADP binding
C	0045259	cellular_component	proton-transporting ATP synthase complex
C	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
C	0046034	biological_process	ATP metabolic process
C	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
C	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
C	1902600	biological_process	proton transmembrane transport
D	0005524	molecular_function	ATP binding
D	0005886	cellular_component	plasma membrane
D	0006754	biological_process	ATP biosynthetic process
D	0015986	biological_process	proton motive force-driven ATP synthesis
D	0016887	molecular_function	ATP hydrolysis activity
D	0045259	cellular_component	proton-transporting ATP synthase complex
D	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
D	0046034	biological_process	ATP metabolic process
D	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
D	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
D	1902600	biological_process	proton transmembrane transport
E	0005524	molecular_function	ATP binding
E	0005886	cellular_component	plasma membrane
E	0006754	biological_process	ATP biosynthetic process
E	0015986	biological_process	proton motive force-driven ATP synthesis
E	0016887	molecular_function	ATP hydrolysis activity
E	0045259	cellular_component	proton-transporting ATP synthase complex
E	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
E	0046034	biological_process	ATP metabolic process
E	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
E	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
E	1902600	biological_process	proton transmembrane transport
F	0005524	molecular_function	ATP binding
F	0005886	cellular_component	plasma membrane
F	0006754	biological_process	ATP biosynthetic process
F	0015986	biological_process	proton motive force-driven ATP synthesis
F	0016887	molecular_function	ATP hydrolysis activity
F	0045259	cellular_component	proton-transporting ATP synthase complex
F	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
F	0046034	biological_process	ATP metabolic process
F	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
F	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
F	1902600	biological_process	proton transmembrane transport
G	0005524	molecular_function	ATP binding
G	0005886	cellular_component	plasma membrane
G	0006754	biological_process	ATP biosynthetic process
G	0015986	biological_process	proton motive force-driven ATP synthesis
G	0042777	biological_process	proton motive force-driven plasma membrane ATP synthesis
G	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
G	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
G	1902600	biological_process	proton transmembrane transport
H	0005524	molecular_function	ATP binding
H	0005886	cellular_component	plasma membrane
H	0006754	biological_process	ATP biosynthetic process
H	0015986	biological_process	proton motive force-driven ATP synthesis
H	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
H	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
H	1902600	biological_process	proton transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	binding site for residue ADP A 1600

Chain	Residue
A	ASP173
A	GLN435
A	MG1601
A	HOH1701
A	HOH1703
A	HOH1704
D	ASP357
D	TYR366
A	LYS175
A	THR176
A	GLY177
A	LYS178
A	THR179
A	PHE360
A	ARG365
A	GLN433

site_id	AC2
Number of Residues	6
Details	binding site for residue MG A 1601

Chain	Residue
A	THR179
A	ADP1600
A	HOH1701
A	HOH1702
A	HOH1703
A	HOH1704

site_id	AC3
Number of Residues	15
Details	binding site for residue ADP B 600

Chain	Residue
B	ASP173
B	LYS175
B	THR176
B	GLY177
B	LYS178
B	THR179
B	ALA180
B	PHE360
B	ARG365
B	GLN433
B	GLN435
B	MG601
B	HOH701
B	HOH703
B	HOH704

site_id	AC4
Number of Residues	6
Details	binding site for residue MG B 601

Chain	Residue
B	THR179
B	ADP600
B	HOH701
B	HOH702
B	HOH703
B	HOH704

site_id	AC5
Number of Residues	17
Details	binding site for residue ADP C 600

Chain	Residue
C	ASP173
C	LYS175
C	THR176
C	GLY177
C	LYS178
C	THR179
C	ALA180
C	PHE360
C	ARG365
C	GLN433
C	GLN435
C	MG601
C	HOH701
C	HOH703
C	HOH704
F	ASP357
F	TYR366

site_id	AC6
Number of Residues	6
Details	binding site for residue MG C 601

Chain	Residue
C	THR179
C	ADP600
C	HOH701
C	HOH702
C	HOH703
C	HOH704

site_id	AC7
Number of Residues	15
Details	binding site for residue ADP D 600

Chain	Residue
C	VAL374
C	SER375
C	ARG376
D	GLY163
D	VAL164
D	GLY165
D	LYS166
D	THR167
D	VAL168
D	GLU196
D	PHE343
D	PHE422
D	MG601
D	HOH701
D	HOH703

site_id	AC8
Number of Residues	8
Details	binding site for residue MG D 601

Chain	Residue
D	THR167
D	GLU192
D	ARG193
D	ADP600
D	HOH701
D	HOH702
D	HOH703
D	HOH704

site_id	AC9
Number of Residues	4
Details	binding site for residue PO4 E 602

Chain	Residue
E	ARG193
E	ASP254
E	ASN255
E	ARG258

site_id	AD1
Number of Residues	14
Details	binding site for residue ADP F 600

Chain	Residue
F	THR167
F	VAL168
F	PHE343
F	MET416
F	PHE422
F	MG601
F	HOH701
F	HOH704
B	VAL374
B	ARG376
F	GLY163
F	VAL164
F	GLY165
F	LYS166

site_id	AD2
Number of Residues	7
Details	binding site for residue MG F 601

Chain	Residue
F	THR167
F	ARG193
F	ADP600
F	HOH701
F	HOH702
F	HOH703
F	HOH704

Functional Information from PROSITE/UniProt

site_id	PS00152
Number of Residues	10
Details	ATPASE_ALPHA_BETA ATP synthase alpha and beta subunits signature. PAINVGVSVS

Chain	Residue	Details
A	PRO366-SER375
D	PRO344-SER353

site_id	PS00153
Number of Residues	14
Details	ATPASE_GAMMA ATP synthase gamma subunit signature. ITqEisEivgGAnA

Chain	Residue	Details
G	ILE289-ALA302

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_01347

Chain	Residue	Details
D	GLY160
E	GLY160
F	GLY160

site_id	SWS_FT_FI2
Number of Residues	3
Details	SITE: Required for activity => ECO:0000255\|HAMAP-Rule:MF_01346

Chain	Residue	Details
A	SER373
B	SER373
C	SER373

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)