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6FIE

Crystallographic structure of calcium loaded Calbindin-D28K.

Functional Information from GO Data
ChainGOidnamespacecontents
B0005499molecular_functionvitamin D binding
B0005509molecular_functioncalcium ion binding
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0007611biological_processlearning or memory
B0007614biological_processshort-term memory
B0007616biological_processlong-term memory
B0007626biological_processlocomotory behavior
B0008270molecular_functionzinc ion binding
B0010842biological_processretina layer formation
B0010996biological_processresponse to auditory stimulus
B0030424cellular_componentaxon
B0030425cellular_componentdendrite
B0032420cellular_componentstereocilium
B0032437cellular_componentcuticular plate
B0035502biological_processmetanephric part of ureteric bud development
B0043005cellular_componentneuron projection
B0043025cellular_componentneuronal cell body
B0043195cellular_componentterminal bouton
B0043197cellular_componentdendritic spine
B0044305cellular_componentcalyx of Held
B0045202cellular_componentsynapse
B0046872molecular_functionmetal ion binding
B0048167biological_processregulation of synaptic plasticity
B0055074biological_processcalcium ion homeostasis
B0060041biological_processretina development in camera-type eye
B0070062cellular_componentextracellular exosome
B0072205biological_processmetanephric collecting duct development
B0072221biological_processmetanephric distal convoluted tubule development
B0072286biological_processmetanephric connecting tubule development
B0090102biological_processcochlea development
B0098686cellular_componenthippocampal mossy fiber to CA3 synapse
B0098794cellular_componentpostsynapse
B0098978cellular_componentglutamatergic synapse
B0098982cellular_componentGABA-ergic synapse
B0099509biological_processregulation of presynaptic cytosolic calcium ion concentration
B0099523cellular_componentpresynaptic cytosol
B0099524cellular_componentpostsynaptic cytosol
B0099534molecular_functioncalcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration
B0099566biological_processregulation of postsynaptic cytosolic calcium ion concentration
B0099567molecular_functioncalcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration
B1900271biological_processregulation of long-term synaptic potentiation
Functional Information from PDB Data
site_idAC1
Number of Residues6
Detailsbinding site for residue CA B 301
ChainResidue
BASP199
BASP201
BASN203
BTYR205
BGLU210
BHOH442

site_idAC2
Number of Residues6
Detailsbinding site for residue CA B 302
ChainResidue
BPHE117
BGLU119
BGLU122
BASP111
BASP113
BSER115

site_idAC3
Number of Residues6
Detailsbinding site for residue CA B 303
ChainResidue
BASP155
BASN157
BASP159
BLYS161
BGLU166
BHOH439

site_idAC4
Number of Residues5
Detailsbinding site for residue CA B 304
ChainResidue
BASP24
BASP26
BSER28
BTYR30
BGLU35

site_idAC5
Number of Residues4
Detailsbinding site for residue SCN B 305
ChainResidue
BALA50
BGLY51
BASN203
BTYR205

Functional Information from PROSITE/UniProt
site_idPS00018
Number of Residues13
DetailsEF_HAND_1 EF-hand calcium-binding domain. DADGSGYLEgkEL
ChainResidueDetails
BASP24-LEU36
BASP111-LEU123
BASP155-MET167
BASP199-LEU211

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues19
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448, ECO:0000269|PubMed:30289411, ECO:0007744|PDB:6FIE
ChainResidueDetails
BASP24
BASP155
BASN157
BASP159
BLYS161
BGLU166
BASP199
BASP201
BASN203
BTYR205
BGLU210
BASP26
BSER28
BTYR30
BGLU35
BASP111
BASP113
BSER115
BGLU122

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: N-acetylalanine => ECO:0000250|UniProtKB:P04467
ChainResidueDetails
BALA2

227111

PDB entries from 2024-11-06

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