6FG1
CRYSTAL STRUCTURE OF FAB OF NATALIZUMAB IN COMPLEX WITH FAB OF NAA32.
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue GOL H 301 |
| Chain | Residue |
| H | PHE176 |
| L | SER176 |
| L | THR177 |
| H | PRO177 |
| H | VAL179 |
| H | SER187 |
| H | LEU188 |
| H | SER189 |
| L | GLN159 |
| L | SER161 |
| L | SER175 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL H 302 |
| Chain | Residue |
| H | VAL93 |
| H | GLN115 |
| H | GLY116 |
| H | THR117 |
| H | LEU118 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue GOL L 301 |
| Chain | Residue |
| A | ASN169 |
| A | GLN206 |
| A | THR207 |
| A | HOH358 |
| L | GLU160 |
| L | VAL162 |
| L | HOH470 |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH |
| Chain | Residue | Details |
| L | TYR191-HIS197 | |
| D | TYR193-HIS199 | |
| A | TYR208-HIS214 | |
| H | TYR204-HIS210 |
