Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| B | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| B | 0007165 | biological_process | signal transduction |
| B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue GAI A 1001 |
| Chain | Residue |
| A | ASP762 |
| A | LEU764 |
| A | GLU765 |
| A | ARG769 |
| A | ARG918 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue D5T A 1002 |
| Chain | Residue |
| A | GLN874 |
| A | GLY876 |
| A | PHE880 |
| A | HOH1174 |
| A | MET785 |
| A | ALA837 |
| A | VAL840 |
| A | MET861 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue GAI A 1003 |
| Chain | Residue |
| A | SER798 |
| A | ALA799 |
| A | ASP801 |
| A | GLN802 |
| A | SER804 |
| A | PHE809 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue GAI A 1004 |
| Chain | Residue |
| A | VAL610 |
| A | HOH1107 |
| A | HOH1173 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue ZN A 1005 |
| Chain | Residue |
| A | HIS673 |
| A | HIS709 |
| A | ASP710 |
| A | ASP822 |
| A | HOH1133 |
| A | HOH1150 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1006 |
| Chain | Residue |
| A | ASP710 |
| A | HOH1118 |
| A | HOH1133 |
| A | HOH1141 |
| A | HOH1169 |
| A | HOH1176 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue GAI A 1007 |
| Chain | Residue |
| A | SER726 |
| A | PRO727 |
| A | LEU728 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 1001 |
| Chain | Residue |
| B | ASP710 |
| B | HOH1119 |
| B | HOH1123 |
| B | HOH1138 |
| B | HOH1154 |
| B | HOH1158 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue ZN B 1002 |
| Chain | Residue |
| B | HIS673 |
| B | HIS709 |
| B | ASP710 |
| B | ASP822 |
| B | HOH1123 |
| B | HOH1151 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue GOL B 1003 |
| Chain | Residue |
| B | TYR691 |
| B | LEU694 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue GAI B 1004 |
| Chain | Residue |
| B | ASP762 |
| B | LEU764 |
| B | GLU765 |
| B | ARG769 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue GAI B 1005 |
| Chain | Residue |
| B | GLY688 |
| B | ASN689 |
| B | GLY896 |
| B | HOH1156 |
| site_id | AD4 |
| Number of Residues | 10 |
| Details | binding site for residue D5T B 1006 |
| Chain | Residue |
| B | HIS669 |
| B | MET785 |
| B | ASP822 |
| B | ASN825 |
| B | TRP836 |
| B | ALA837 |
| B | MET861 |
| B | GLN874 |
| B | PHE877 |
| B | HOH1134 |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDLdHmGlnNsF |
| Chain | Residue | Details |
| A | HIS709-PHE720 | |
