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6F9K

Tryptophan Repressor TrpR from E.coli with 5-methyl-L-tryptophan as ligand

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0003700molecular_functionDNA-binding transcription factor activity
A0005737cellular_componentcytoplasm
A0006355biological_processregulation of DNA-templated transcription
A0043565molecular_functionsequence-specific DNA binding
A0045892biological_processnegative regulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues12
Detailsbinding site for residue D0Q A 201
ChainResidue
AASN40
ASO4205
AHOH311
AHOH332
ALEU41
ALEU43
ATHR44
AARG54
AVAL58
AARG84
AGLY85
ASER88

site_idAC2
Number of Residues9
Detailsbinding site for residue SO4 A 202
ChainResidue
ATHR44
AASP46
AGLU47
ATHR83
AASN87
AD0Q207
AHOH305
AHOH322
AHOH323

site_idAC3
Number of Residues8
Detailsbinding site for residue SO4 A 203
ChainResidue
AARG15
APRO45
AARG48
ALYS90
AALA91
AHOH313
AHOH317
AHOH343

site_idAC4
Number of Residues5
Detailsbinding site for residue SO4 A 204
ChainResidue
AGLN14
AGLU18
AARG21
AARG56
AGLU74

site_idAC5
Number of Residues5
Detailsbinding site for residue SO4 A 205
ChainResidue
ATHR81
AARG84
AD0Q201
AHOH302
AHOH305

site_idAC6
Number of Residues9
Detailsbinding site for residue D0Q A 206
ChainResidue
AGLN3
APRO6
ALEU61
ALEU62
AGLY64
AGLU102
ALYS106
AD0Q208
AHOH314

site_idAC7
Number of Residues9
Detailsbinding site for residue D0Q A 207
ChainResidue
ALEU43
ALEU43
AGLU47
AGLU47
AALA50
AALA50
AARG54
AARG54
ASO4202

site_idAC8
Number of Residues9
Detailsbinding site for residue D0Q A 208
ChainResidue
AGLN3
ATYR7
AGLU49
AGLN68
ALYS90
AD0Q206
AHOH312
AHOH314
AHOH338

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues23
DetailsDNA_BIND:
ChainResidueDetails
AGLN68-ALA91

227933

PDB entries from 2024-11-27

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