6F92
Structure of the family GH92 alpha-mannosidase BT3965 from Bacteroides thetaiotaomicron in complex with Mannoimidazole (ManI)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000224 | molecular_function | peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006516 | biological_process | glycoprotein catabolic process |
| A | 0030246 | molecular_function | carbohydrate binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000224 | molecular_function | peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006516 | biological_process | glycoprotein catabolic process |
| B | 0030246 | molecular_function | carbohydrate binding |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000224 | molecular_function | peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0006516 | biological_process | glycoprotein catabolic process |
| C | 0030246 | molecular_function | carbohydrate binding |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000224 | molecular_function | peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0006516 | biological_process | glycoprotein catabolic process |
| D | 0030246 | molecular_function | carbohydrate binding |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 801 |
| Chain | Residue |
| A | PRO96 |
| A | ASP97 |
| A | GLY99 |
| A | ARG101 |
| A | HOH1059 |
| A | HOH1449 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue CA A 802 |
| Chain | Residue |
| A | MVL804 |
| A | HOH1080 |
| A | HOH1106 |
| A | HOH1117 |
| A | ASN590 |
| A | GLU591 |
| A | ASP633 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue CL A 803 |
| Chain | Residue |
| A | LYS408 |
| A | PRO653 |
| A | SER654 |
| A | ASN656 |
| A | HOH967 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | binding site for residue MVL A 804 |
| Chain | Residue |
| A | THR69 |
| A | GLY70 |
| A | TRP184 |
| A | SER341 |
| A | TRP343 |
| A | ASP344 |
| A | TRP383 |
| A | MET393 |
| A | GLU531 |
| A | ASN590 |
| A | GLU591 |
| A | ASP633 |
| A | CA802 |
| A | HOH1060 |
| A | HOH1080 |
| A | HOH1117 |
| A | HOH1297 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 805 |
| Chain | Residue |
| A | TYR463 |
| A | GLN543 |
| A | PRO739 |
| A | ILE741 |
| A | HOH971 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue NA B 801 |
| Chain | Residue |
| B | PRO96 |
| B | GLY99 |
| B | ARG101 |
| B | HOH1038 |
| B | HOH1351 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue CA B 802 |
| Chain | Residue |
| B | ASN590 |
| B | GLU591 |
| B | ASP633 |
| B | MVL804 |
| B | HOH1030 |
| B | HOH1079 |
| B | HOH1203 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 803 |
| Chain | Residue |
| B | LYS408 |
| B | PRO653 |
| B | SER654 |
| B | ASN656 |
| site_id | AC9 |
| Number of Residues | 16 |
| Details | binding site for residue MVL B 804 |
| Chain | Residue |
| B | THR69 |
| B | GLY70 |
| B | TRP184 |
| B | SER341 |
| B | TRP343 |
| B | ASP344 |
| B | TRP383 |
| B | GLU531 |
| B | ASN590 |
| B | GLU591 |
| B | ASP633 |
| B | CA802 |
| B | HOH1018 |
| B | HOH1030 |
| B | HOH1192 |
| B | HOH1203 |
| site_id | AD1 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 805 |
| Chain | Residue |
| B | SER42 |
| B | ARG43 |
| B | ASN155 |
| B | HIS156 |
| B | THR157 |
| B | GLN160 |
| B | HOH1222 |
| B | HOH1290 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 806 |
| Chain | Residue |
| B | GLU332 |
| B | GLY333 |
| B | ASN366 |
| B | ARG417 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue NA C 801 |
| Chain | Residue |
| C | PRO96 |
| C | GLY99 |
| C | ARG101 |
| C | HOH991 |
| C | HOH1191 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue CA C 802 |
| Chain | Residue |
| C | ASN590 |
| C | GLU591 |
| C | ASP633 |
| C | MVL804 |
| C | HOH958 |
| C | HOH961 |
| C | HOH1131 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue CL C 803 |
| Chain | Residue |
| C | ASN656 |
| C | LYS408 |
| C | PRO653 |
| C | SER654 |
| site_id | AD6 |
| Number of Residues | 17 |
| Details | binding site for residue MVL C 804 |
| Chain | Residue |
| C | THR69 |
| C | GLY70 |
| C | TRP184 |
| C | SER341 |
| C | TRP343 |
| C | ASP344 |
| C | TRP383 |
| C | MET393 |
| C | GLU531 |
| C | ASN590 |
| C | GLU591 |
| C | ASP633 |
| C | CA802 |
| C | HOH957 |
| C | HOH958 |
| C | HOH1131 |
| C | HOH1169 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue NA D 801 |
| Chain | Residue |
| D | PRO96 |
| D | GLY99 |
| D | ARG101 |
| D | HOH1114 |
| D | HOH1469 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue CA D 802 |
| Chain | Residue |
| D | ASN590 |
| D | GLU591 |
| D | ASP633 |
| D | MVL804 |
| D | HOH983 |
| D | HOH1049 |
| D | HOH1080 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue CL D 803 |
| Chain | Residue |
| D | LYS408 |
| D | PRO653 |
| D | SER654 |
| D | ASN656 |
| D | HOH1153 |
| site_id | AE1 |
| Number of Residues | 16 |
| Details | binding site for residue MVL D 804 |
| Chain | Residue |
| D | THR69 |
| D | GLY70 |
| D | TRP184 |
| D | SER341 |
| D | TRP343 |
| D | ASP344 |
| D | TRP383 |
| D | GLU531 |
| D | ASN590 |
| D | GLU591 |
| D | ASP633 |
| D | CA802 |
| D | HOH1049 |
| D | HOH1080 |
| D | HOH1120 |
| D | HOH1317 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO D 805 |
| Chain | Residue |
| D | LYS497 |
| D | TYR498 |
| D | THR538 |
| D | TRP539 |
| D | TYR548 |
| D | ARG560 |
| site_id | AE3 |
| Number of Residues | 1 |
| Details | binding site for residue NO3 D 806 |
| Chain | Residue |
| D | ARG294 |
| site_id | AE4 |
| Number of Residues | 7 |
| Details | binding site for residue NO3 D 807 |
| Chain | Residue |
| D | SER42 |
| D | ARG43 |
| D | ASN155 |
| D | HIS156 |
| D | THR157 |
| D | HOH956 |
| D | HOH1123 |
