Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue CVE A 501 |
| Chain | Residue |
| A | ASP119 |
| B | SER339 |
| B | TRP340 |
| B | ARG341 |
| B | HIS342 |
| B | MET345 |
| B | GLY346 |
| B | SER347 |
| B | VAL348 |
| B | ARG383 |
| A | PRO121 |
| A | ARG179 |
| A | GLN283 |
| A | CYS285 |
| A | HOH605 |
| A | HOH642 |
| A | HOH669 |
| A | HOH718 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 502 |
| Chain | Residue |
| A | ILE239 |
| A | ARG240 |
| A | GLY242 |
| A | CYS285 |
| A | ARG286 |
| A | HOH676 |
| A | HOH694 |
| A | HOH708 |
Functional Information from PROSITE/UniProt
| site_id | PS00455 |
| Number of Residues | 12 |
| Details | AMP_BINDING Putative AMP-binding domain signature. MPTSSGSEGnVK |
| Chain | Residue | Details |
| A | MET123-LYS134 | |
| site_id | PS01121 |
| Number of Residues | 15 |
| Details | CASPASE_HIS Caspase family histidine active site. HktsdStfLvFMSHG |
| Chain | Residue | Details |
| A | HIS224-GLY238 | |
| site_id | PS01122 |
| Number of Residues | 12 |
| Details | CASPASE_CYS Caspase family cysteine active site. KPKVIIIQACRG |
| Chain | Residue | Details |
| A | LYS276-GLY287 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS237 | |
| Chain | Residue | Details |
| A | CYS285 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:30065070 |
| Chain | Residue | Details |
| A | LYS134 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 1 |
| Details | M-CSA 718 |
| Chain | Residue | Details |
| B | GLU390 | electrostatic stabiliser |
| A | GLY238 | electrostatic stabiliser |
| A | CYS285 | nucleofuge, nucleophile, proton acceptor, proton donor |
| A | ARG286 | electrostatic stabiliser |
