6F2C
Methylglyoxal synthase MgsA from Bacillus subtilis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005829 | cellular_component | cytosol |
| A | 0008929 | molecular_function | methylglyoxal synthase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019242 | biological_process | methylglyoxal biosynthetic process |
| B | 0005829 | cellular_component | cytosol |
| B | 0008929 | molecular_function | methylglyoxal synthase activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0019242 | biological_process | methylglyoxal biosynthetic process |
| C | 0005829 | cellular_component | cytosol |
| C | 0008929 | molecular_function | methylglyoxal synthase activity |
| C | 0016829 | molecular_function | lyase activity |
| C | 0019242 | biological_process | methylglyoxal biosynthetic process |
| D | 0005829 | cellular_component | cytosol |
| D | 0008929 | molecular_function | methylglyoxal synthase activity |
| D | 0016829 | molecular_function | lyase activity |
| D | 0019242 | biological_process | methylglyoxal biosynthetic process |
| E | 0005829 | cellular_component | cytosol |
| E | 0008929 | molecular_function | methylglyoxal synthase activity |
| E | 0016829 | molecular_function | lyase activity |
| E | 0019242 | biological_process | methylglyoxal biosynthetic process |
| F | 0005829 | cellular_component | cytosol |
| F | 0008929 | molecular_function | methylglyoxal synthase activity |
| F | 0016829 | molecular_function | lyase activity |
| F | 0019242 | biological_process | methylglyoxal biosynthetic process |
| G | 0005829 | cellular_component | cytosol |
| G | 0008929 | molecular_function | methylglyoxal synthase activity |
| G | 0016829 | molecular_function | lyase activity |
| G | 0019242 | biological_process | methylglyoxal biosynthetic process |
| H | 0005829 | cellular_component | cytosol |
| H | 0008929 | molecular_function | methylglyoxal synthase activity |
| H | 0016829 | molecular_function | lyase activity |
| H | 0019242 | biological_process | methylglyoxal biosynthetic process |
| I | 0005829 | cellular_component | cytosol |
| I | 0008929 | molecular_function | methylglyoxal synthase activity |
| I | 0016829 | molecular_function | lyase activity |
| I | 0019242 | biological_process | methylglyoxal biosynthetic process |
| J | 0005829 | cellular_component | cytosol |
| J | 0008929 | molecular_function | methylglyoxal synthase activity |
| J | 0016829 | molecular_function | lyase activity |
| J | 0019242 | biological_process | methylglyoxal biosynthetic process |
| K | 0005829 | cellular_component | cytosol |
| K | 0008929 | molecular_function | methylglyoxal synthase activity |
| K | 0016829 | molecular_function | lyase activity |
| K | 0019242 | biological_process | methylglyoxal biosynthetic process |
| L | 0005829 | cellular_component | cytosol |
| L | 0008929 | molecular_function | methylglyoxal synthase activity |
| L | 0016829 | molecular_function | lyase activity |
| L | 0019242 | biological_process | methylglyoxal biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 201 |
| Chain | Residue |
| A | GLY35 |
| A | ARG51 |
| A | PHE52 |
| G | VAL0 |
| G | LYS27 |
| G | ASN28 |
| G | HIS29 |
| G | ASP30 |
| G | GLN48 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 202 |
| Chain | Residue |
| A | HIS8 |
| A | ASP9 |
| A | GLN85 |
| A | CL203 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue CL A 203 |
| Chain | Residue |
| A | GLY55 |
| A | GOL202 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue CL D 201 |
| Chain | Residue |
| D | LYS12 |
| D | GLY35 |
| D | SER54 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue CL D 202 |
| Chain | Residue |
| D | HOH332 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue CL D 203 |
| Chain | Residue |
| D | HIS8 |
| D | ASP9 |
| D | GLN85 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 201 |
| Chain | Residue |
| B | LYS12 |
| B | THR34 |
| B | GLY35 |
| B | THR36 |
| B | THR37 |
| B | SER54 |
| B | GLY55 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 202 |
| Chain | Residue |
| B | HIS42 |
| B | LEU47 |
| B | GLN48 |
| B | ILE49 |
| B | ARG51 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | binding site for residue CL F 201 |
| Chain | Residue |
| F | ILE49 |
| site_id | AD1 |
| Number of Residues | 11 |
| Details | binding site for residue GOL C 201 |
| Chain | Residue |
| C | ALA7 |
| C | LYS12 |
| C | THR34 |
| C | GLY35 |
| C | THR36 |
| C | THR37 |
| C | SER54 |
| C | GLY55 |
| C | HOH303 |
| C | HOH304 |
| C | HOH353 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue CL C 202 |
| Chain | Residue |
| C | ILE49 |
| C | ARG51 |
| site_id | AD3 |
| Number of Residues | 1 |
| Details | binding site for residue CL E 201 |
| Chain | Residue |
| E | GLN85 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue GOL E 202 |
| Chain | Residue |
| D | ALA68 |
| E | ARG51 |
| E | GLN53 |
| E | GLN62 |
| E | HOH308 |
| site_id | AD5 |
| Number of Residues | 8 |
| Details | binding site for residue GOL E 203 |
| Chain | Residue |
| E | LYS27 |
| E | HIS29 |
| E | GLN48 |
| E | HOH310 |
| E | HOH317 |
| J | GLY35 |
| J | ARG51 |
| J | PHE52 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue CL H 201 |
| Chain | Residue |
| H | LYS12 |
| H | THR34 |
| H | SER54 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL H 202 |
| Chain | Residue |
| H | HIS42 |
| H | GLN48 |
| H | ILE49 |
| H | ARG51 |
| site_id | AD8 |
| Number of Residues | 3 |
| Details | binding site for residue CL H 203 |
| Chain | Residue |
| H | GLN85 |
| H | GLU88 |
| H | HOH326 |
| site_id | AD9 |
| Number of Residues | 1 |
| Details | binding site for residue CL K 201 |
| Chain | Residue |
| K | LYS12 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue CL G 201 |
| Chain | Residue |
| A | HOH326 |
| G | ILE49 |
| G | ARG51 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue CL G 202 |
| Chain | Residue |
| G | HIS8 |
| G | ASP9 |
| G | GLN85 |
| G | HOH356 |
| G | HOH360 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue CL G 203 |
| Chain | Residue |
| G | LYS12 |
| G | GLY35 |
| G | SER54 |
| G | HOH350 |
| site_id | AE4 |
| Number of Residues | 2 |
| Details | binding site for residue CL I 202 |
| Chain | Residue |
| I | HOH311 |
| L | ILE49 |
| site_id | AE5 |
| Number of Residues | 2 |
| Details | binding site for residue CL I 203 |
| Chain | Residue |
| L | LYS27 |
| L | HOH340 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue CL I 204 |
| Chain | Residue |
| I | HIS8 |
| I | ASP9 |
| I | GLN85 |
| L | GLN48 |
| site_id | AE7 |
| Number of Residues | 5 |
| Details | binding site for residue GOL L 201 |
| Chain | Residue |
| L | HIS8 |
| L | ASP9 |
| L | GLN85 |
| L | PRO86 |
| L | HOH335 |
| site_id | AE8 |
| Number of Residues | 2 |
| Details | binding site for residue CL L 202 |
| Chain | Residue |
| L | GLY35 |
| L | LYS12 |
Functional Information from PROSITE/UniProt
| site_id | PS01335 |
| Number of Residues | 9 |
| Details | METHYLGLYOXAL_SYNTH Methylglyoxal synthase active site. SGPLGGDqQ |
| Chain | Residue | Details |
| A | SER54-GLN62 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_00549 |
| Chain | Residue | Details |
| A | ASP60 | |
| I | ASP60 | |
| L | ASP60 | |
| J | ASP60 | |
| D | ASP60 | |
| B | ASP60 | |
| F | ASP60 | |
| C | ASP60 | |
| E | ASP60 | |
| H | ASP60 | |
| K | ASP60 | |
| G | ASP60 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 60 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00549 |
| Chain | Residue | Details |
| A | HIS8 | |
| D | HIS87 | |
| B | HIS8 | |
| B | LYS12 | |
| B | THR34 | |
| B | SER54 | |
| B | HIS87 | |
| F | HIS8 | |
| F | LYS12 | |
| F | THR34 | |
| F | SER54 | |
| A | LYS12 | |
| F | HIS87 | |
| C | HIS8 | |
| C | LYS12 | |
| C | THR34 | |
| C | SER54 | |
| C | HIS87 | |
| E | HIS8 | |
| E | LYS12 | |
| E | THR34 | |
| E | SER54 | |
| A | THR34 | |
| E | HIS87 | |
| H | HIS8 | |
| H | LYS12 | |
| H | THR34 | |
| H | SER54 | |
| H | HIS87 | |
| K | HIS8 | |
| K | LYS12 | |
| K | THR34 | |
| K | SER54 | |
| A | SER54 | |
| K | HIS87 | |
| G | HIS8 | |
| G | LYS12 | |
| G | THR34 | |
| G | SER54 | |
| G | HIS87 | |
| I | HIS8 | |
| I | LYS12 | |
| I | THR34 | |
| I | SER54 | |
| A | HIS87 | |
| I | HIS87 | |
| L | HIS8 | |
| L | LYS12 | |
| L | THR34 | |
| L | SER54 | |
| L | HIS87 | |
| J | HIS8 | |
| J | LYS12 | |
| J | THR34 | |
| J | SER54 | |
| D | HIS8 | |
| J | HIS87 | |
| D | LYS12 | |
| D | THR34 | |
| D | SER54 |
