Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue HEC A 301 |
| Chain | Residue |
| A | TYR34 |
| B | ALA880 |
| B | ASN895 |
| B | ARG896 |
| C | TRP148 |
| C | MET158 |
| D | TYR101 |
| E | HIS35 |
| E | ASN37 |
| A | TYR120 |
| A | ALA121 |
| A | MET156 |
| A | ASN205 |
| A | CYS206 |
| A | CYS209 |
| A | HIS210 |
| A | HEC302 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | binding site for residue HEC A 302 |
| Chain | Residue |
| A | HIS122 |
| A | PHE123 |
| A | SER127 |
| A | HIS128 |
| A | ASN131 |
| A | CYS138 |
| A | CYS159 |
| A | CYS162 |
| A | HIS163 |
| A | TYR169 |
| A | LEU170 |
| A | ILE200 |
| A | PRO203 |
| A | HEC301 |
| A | HEC303 |
| B | TYR793 |
| B | ARG954 |
| B | ARG958 |
| B | ASN961 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | binding site for residue HEC A 303 |
| Chain | Residue |
| A | HIS65 |
| A | LYS73 |
| A | ALA74 |
| A | LYS113 |
| A | HIS115 |
| A | LEU117 |
| A | PHE123 |
| A | HIS125 |
| A | VAL133 |
| A | GLY134 |
| A | CYS135 |
| A | CYS138 |
| A | HIS139 |
| A | LEU154 |
| A | HEC302 |
| A | HEC304 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | binding site for residue HEC A 304 |
| Chain | Residue |
| A | TYR44 |
| A | TYR48 |
| A | HIS50 |
| A | CYS61 |
| A | CYS64 |
| A | HIS65 |
| A | ILE76 |
| A | TRP111 |
| A | LYS113 |
| A | VAL114 |
| A | HIS139 |
| A | ILE142 |
| A | HEC303 |
| A | HEC305 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | binding site for residue HEC A 305 |
| Chain | Residue |
| A | PRO47 |
| A | TYR48 |
| A | ILE52 |
| A | HIS53 |
| A | LYS56 |
| A | LEU57 |
| A | CYS82 |
| A | CYS85 |
| A | HIS86 |
| A | ILE89 |
| A | SER93 |
| A | ARG95 |
| A | HEC304 |
| E | TYR133 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | binding site for residue F3S B 1101 |
| Chain | Residue |
| B | CYS877 |
| B | MET892 |
| B | CYS897 |
| B | GLY899 |
| B | THR900 |
| B | ARG901 |
| B | TYR902 |
| B | CYS903 |
| B | ARG912 |
| B | MET943 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue SF4 B 1102 |
| Chain | Residue |
| B | CYS865 |
| B | MET866 |
| B | HIS867 |
| B | CYS868 |
| B | CYS873 |
| B | ASN890 |
| B | CYS907 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue SF4 B 1103 |
| Chain | Residue |
| B | CYS946 |
| B | TYR948 |
| B | CYS949 |
| B | ALA975 |
| B | CYS976 |
| B | CYS817 |
| B | TRP839 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | binding site for residue SF4 B 1104 |
| Chain | Residue |
| B | CYS807 |
| B | THR808 |
| B | GLY809 |
| B | CYS810 |
| B | ASN811 |
| B | ALA812 |
| B | CYS813 |
| B | ILE842 |
| B | CYS980 |
| site_id | AD1 |
| Number of Residues | 14 |
| Details | binding site for residue HEC E 400 |
| Chain | Residue |
| E | CYS114 |
| E | CYS117 |
| E | HIS118 |
| E | TYR135 |
| E | THR136 |
| E | ALA138 |
| E | PHE141 |
| E | LEU146 |
| E | TYR153 |
| E | ILE158 |
| E | ARG163 |
| E | ASN164 |
| E | MET165 |
| E | TYR168 |
