Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| B | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| B | 0007165 | biological_process | signal transduction |
| B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue ZN A 701 |
| Chain | Residue |
| A | HIS421 |
| A | HIS457 |
| A | ASP458 |
| A | ASP575 |
| A | CMP703 |
| A | HOH802 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 702 |
| Chain | Residue |
| A | HOH806 |
| A | HOH814 |
| A | HOH815 |
| A | ASP458 |
| A | CMP703 |
| A | HOH802 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | binding site for residue CMP A 703 |
| Chain | Residue |
| A | HIS417 |
| A | HIS421 |
| A | ASP458 |
| A | ASP575 |
| A | LEU576 |
| A | ASN578 |
| A | LEU593 |
| A | MET614 |
| A | GLN626 |
| A | PHE629 |
| A | ZN701 |
| A | MG702 |
| A | HOH801 |
| A | HOH802 |
| A | HOH804 |
| A | HOH810 |
| A | HOH814 |
| A | HOH818 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue ZN B 701 |
| Chain | Residue |
| B | HIS421 |
| B | HIS457 |
| B | ASP458 |
| B | ASP575 |
| B | AMP703 |
| B | HOH801 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 702 |
| Chain | Residue |
| B | ASP458 |
| B | AMP703 |
| B | HOH801 |
| B | HOH804 |
| B | HOH806 |
| B | HOH814 |
| site_id | AC6 |
| Number of Residues | 16 |
| Details | binding site for residue AMP B 703 |
| Chain | Residue |
| B | HIS417 |
| B | HIS421 |
| B | ASP458 |
| B | ASP575 |
| B | LEU576 |
| B | ASN578 |
| B | LEU593 |
| B | GLN626 |
| B | PHE629 |
| B | ZN701 |
| B | MG702 |
| B | HOH801 |
| B | HOH804 |
| B | HOH809 |
| B | HOH814 |
| B | HOH815 |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDVdHpGvtNqF |
| Chain | Residue | Details |
| A | HIS457-PHE468 | |
