6EYP
X-ray structure of the unliganded uridine phosphorylase from Vibrio cholerae at 1.22A
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004850 | molecular_function | uridine phosphorylase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0009116 | biological_process | nucleoside metabolic process |
| A | 0009166 | biological_process | nucleotide catabolic process |
| A | 0016763 | molecular_function | pentosyltransferase activity |
| A | 0044206 | biological_process | UMP salvage |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004850 | molecular_function | uridine phosphorylase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0009116 | biological_process | nucleoside metabolic process |
| B | 0009166 | biological_process | nucleotide catabolic process |
| B | 0016763 | molecular_function | pentosyltransferase activity |
| B | 0044206 | biological_process | UMP salvage |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004850 | molecular_function | uridine phosphorylase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0009116 | biological_process | nucleoside metabolic process |
| C | 0009166 | biological_process | nucleotide catabolic process |
| C | 0016763 | molecular_function | pentosyltransferase activity |
| C | 0044206 | biological_process | UMP salvage |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0004850 | molecular_function | uridine phosphorylase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0009116 | biological_process | nucleoside metabolic process |
| D | 0009166 | biological_process | nucleotide catabolic process |
| D | 0016763 | molecular_function | pentosyltransferase activity |
| D | 0044206 | biological_process | UMP salvage |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0004850 | molecular_function | uridine phosphorylase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005829 | cellular_component | cytosol |
| E | 0009116 | biological_process | nucleoside metabolic process |
| E | 0009166 | biological_process | nucleotide catabolic process |
| E | 0016763 | molecular_function | pentosyltransferase activity |
| E | 0044206 | biological_process | UMP salvage |
| F | 0003824 | molecular_function | catalytic activity |
| F | 0004850 | molecular_function | uridine phosphorylase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005829 | cellular_component | cytosol |
| F | 0009116 | biological_process | nucleoside metabolic process |
| F | 0009166 | biological_process | nucleotide catabolic process |
| F | 0016763 | molecular_function | pentosyltransferase activity |
| F | 0044206 | biological_process | UMP salvage |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 301 |
| Chain | Residue |
| A | ILE68 |
| A | GLU195 |
| A | MET196 |
| A | GLU197 |
| A | HOH533 |
| A | HOH542 |
| B | HIS7 |
| B | ARG47 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue NA A 302 |
| Chain | Residue |
| A | ILE68 |
| A | SER72 |
| B | GLU48 |
| B | ILE68 |
| B | SER72 |
| A | GLU48 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 301 |
| Chain | Residue |
| A | HIS7 |
| A | HOH549 |
| B | PHE161 |
| B | GLU195 |
| B | MET196 |
| B | GLU197 |
| B | HOH478 |
| B | HOH486 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue GOL C 301 |
| Chain | Residue |
| C | ILE68 |
| C | PHE161 |
| C | GLU195 |
| C | MET196 |
| C | GLU197 |
| C | HOH491 |
| C | HOH602 |
| C | HOH612 |
| D | HIS7 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue NA C 302 |
| Chain | Residue |
| C | GLU48 |
| C | ILE68 |
| C | SER72 |
| D | GLU48 |
| D | ILE68 |
| D | SER72 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue MG C 303 |
| Chain | Residue |
| C | ASN102 |
| C | HOH427 |
| C | HOH516 |
| C | HOH585 |
| C | HOH603 |
| C | HOH647 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue GOL D 301 |
| Chain | Residue |
| C | HIS7 |
| D | ILE68 |
| D | GLU195 |
| D | MET196 |
| D | GLU197 |
| D | HOH421 |
| D | HOH446 |
| D | HOH487 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | binding site for residue GOL D 302 |
| Chain | Residue |
| D | LEU115 |
| D | ARG178 |
| D | PHE179 |
| D | SER182 |
| D | GLU185 |
| D | HOH402 |
| D | HOH413 |
| D | HOH416 |
| E | PRO124 |
| E | GLU126 |
| F | ARG177 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | binding site for residue GOL E 301 |
| Chain | Residue |
| E | ILE68 |
| E | GLU195 |
| E | MET196 |
| E | GLU197 |
| E | HOH420 |
| E | HOH484 |
| F | HIS7 |
| F | ARG47 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue NA E 302 |
| Chain | Residue |
| E | GLU48 |
| E | ILE68 |
| E | SER72 |
| F | GLU48 |
| F | ILE68 |
| F | SER72 |
| site_id | AD2 |
| Number of Residues | 10 |
| Details | binding site for residue GOL F 301 |
| Chain | Residue |
| E | HIS7 |
| E | ARG47 |
| F | ILE68 |
| F | GLU195 |
| F | MET196 |
| F | GLU197 |
| F | HOH464 |
| F | HOH558 |
| F | HOH564 |
| F | HOH584 |
| site_id | AD3 |
| Number of Residues | 10 |
| Details | binding site for residue GOL F 302 |
| Chain | Residue |
| A | PRO124 |
| A | GLU126 |
| B | ARG177 |
| B | HOH401 |
| F | LEU115 |
| F | ARG178 |
| F | GLU185 |
| F | HOH409 |
| F | HOH443 |
| F | HOH602 |
Functional Information from PROSITE/UniProt
| site_id | PS01232 |
| Number of Residues | 16 |
| Details | PNP_UDP_1 Purine and other phosphorylases family 1 signature. StGIGgPStSIaveEL |
| Chain | Residue | Details |
| A | SER65-LEU80 |
