6EYE

Crystal structure of murine neuroglobin under 150 bar krypton

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001666	biological_process	response to hypoxia
A	0005092	molecular_function	GDP-dissociation inhibitor activity
A	0005344	molecular_function	oxygen carrier activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005759	cellular_component	mitochondrial matrix
A	0005829	cellular_component	cytosol
A	0015671	biological_process	oxygen transport
A	0016491	molecular_function	oxidoreductase activity
A	0019825	molecular_function	oxygen binding
A	0020037	molecular_function	heme binding
A	0046872	molecular_function	metal ion binding
A	0071456	biological_process	cellular response to hypoxia
A	0098809	molecular_function	nitrite reductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue SO4 A 201

Chain	Residue
A	SER19
A	PRO20
A	LEU21
A	GLU22
A	ARG66

---

site_id	AC2
Number of Residues	22
Details	binding site for residue HEM A 202

Chain	Residue
A	LYS67
A	LYS67
A	VAL68
A	VAL71
A	TYR88
A	LEU92
A	LYS95
A	HIS96
A	VAL101
A	KR207
A	KR208
A	KR209
A	KR212
A	KR213
A	HOH301
A	HOH301
A	HOH322
A	HOH330
A	LEU41
A	PHE42
A	TYR44
A	HIS64

---

site_id	AC3
Number of Residues	4
Details	binding site for residue KR A 203

Chain	Residue
A	ALA29
A	PHE32
A	SER55
A	LEU56

---

site_id	AC4
Number of Residues	1
Details	binding site for residue KR A 205

Chain	Residue
A	VAL109

---

site_id	AC5
Number of Residues	4
Details	binding site for residue KR A 206

Chain	Residue
A	GLY110
A	LEU114
A	TRP133
A	TYR137

---

site_id	AC6
Number of Residues	2
Details	binding site for residue KR A 207

Chain	Residue
A	VAL140
A	HEM202

---

site_id	AC7
Number of Residues	3
Details	binding site for residue KR A 208

Chain	Residue
A	PHE28
A	VAL109
A	HEM202

---

site_id	AC8
Number of Residues	5
Details	binding site for residue KR A 209

Chain	Residue
A	LYS67
A	TYR88
A	SER91
A	LEU92
A	HEM202

---

site_id	AC9
Number of Residues	3
Details	binding site for residue KR A 210

Chain	Residue
A	LEU70
A	TYR88
A	KR211

---

site_id	AD1
Number of Residues	1
Details	binding site for residue KR A 211

Chain	Residue
A	KR210

---

site_id	AD2
Number of Residues	4
Details	binding site for residue KR A 212

Chain	Residue
A	LYS95
A	HIS96
A	VAL99
A	HEM202

---

site_id	AD3
Number of Residues	2
Details	binding site for residue KR A 213

Chain	Residue
A	PHE106
A	HEM202

---

site_id	AD4
Number of Residues	2
Details	binding site for residue KR A 214

Chain	Residue
A	LEU82
A	LEU89

---

site_id	AD5
Number of Residues	1
Details	binding site for residue KR A 216

Chain	Residue
A	MET69

---

site_id	AD6
Number of Residues	5
Details	binding site for residue KR A 217

Chain	Residue
A	GLY24
A	LEU27
A	PHE28
A	VAL68
A	MET69

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Binding site: {"description":"distal binding residue; reversible","evidences":[{"source":"PROSITE-ProRule","id":"PRU00238","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15162488","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1Q1F","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"description":"proximal binding residue","evidences":[{"source":"PROSITE-ProRule","id":"PRU00238","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15162488","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15548613","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1Q1F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1W92","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---