6EXF
Crystal structure of the complex Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO5 with Fe(II)/Lysine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016706 | molecular_function | 2-oxoglutarate-dependent dioxygenase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051213 | molecular_function | dioxygenase activity |
| A | 0055114 | biological_process | obsolete oxidation-reduction process |
| B | 0016706 | molecular_function | 2-oxoglutarate-dependent dioxygenase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051213 | molecular_function | dioxygenase activity |
| B | 0055114 | biological_process | obsolete oxidation-reduction process |
| C | 0016706 | molecular_function | 2-oxoglutarate-dependent dioxygenase activity |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0051213 | molecular_function | dioxygenase activity |
| C | 0055114 | biological_process | obsolete oxidation-reduction process |
| D | 0016706 | molecular_function | 2-oxoglutarate-dependent dioxygenase activity |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0051213 | molecular_function | dioxygenase activity |
| D | 0055114 | biological_process | obsolete oxidation-reduction process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue FE A 401 |
| Chain | Residue |
| A | HIS176 |
| A | GLU178 |
| A | HIS312 |
| A | LYS403 |
| A | HOH672 |
| A | HOH684 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue LYS A 402 |
| Chain | Residue |
| A | TYR193 |
| A | SER202 |
| A | THR203 |
| A | GLY313 |
| A | ARG314 |
| A | ARG334 |
| A | MET336 |
| A | HOH512 |
| A | HOH672 |
| A | HOH684 |
| A | VAL154 |
| A | THR165 |
| A | GLY166 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue LYS A 403 |
| Chain | Residue |
| A | GLN144 |
| A | ARG145 |
| A | GLY166 |
| A | SER167 |
| A | ARG338 |
| A | FE401 |
| A | HOH646 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue FE B 401 |
| Chain | Residue |
| B | HIS176 |
| B | GLU178 |
| B | HIS312 |
| B | LYS402 |
| B | HOH634 |
| B | HOH640 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue LYS B 402 |
| Chain | Residue |
| B | GLN144 |
| B | HIS176 |
| B | GLU178 |
| B | ASP230 |
| B | ASP260 |
| B | ARG314 |
| B | ARG338 |
| B | FE401 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue FE C 401 |
| Chain | Residue |
| C | HIS176 |
| C | GLU178 |
| C | HIS312 |
| C | HOH662 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | binding site for residue LYS C 402 |
| Chain | Residue |
| C | GLN144 |
| C | ARG145 |
| C | VAL154 |
| C | THR165 |
| C | GLY166 |
| C | SER167 |
| C | HIS176 |
| C | ASN232 |
| C | ARG338 |
| C | HOH524 |
| C | HOH578 |
| C | HOH619 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue GOL C 403 |
| Chain | Residue |
| C | GLN102 |
| C | ASP103 |
| C | GLY106 |
| C | PRO107 |
| C | ARG195 |
| C | GLU332 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue FE D 401 |
| Chain | Residue |
| D | HIS176 |
| D | GLU178 |
| D | HIS312 |
| D | LYS402 |
| D | HOH673 |
| site_id | AD1 |
| Number of Residues | 10 |
| Details | binding site for residue LYS D 402 |
| Chain | Residue |
| D | GLN164 |
| D | THR165 |
| D | GLY166 |
| D | HIS176 |
| D | GLU178 |
| D | ASP230 |
| D | ASP260 |
| D | ARG338 |
| D | FE401 |
| D | HOH616 |
| site_id | AD2 |
| Number of Residues | 1 |
| Details | binding site for residue GOL D 403 |
| Chain | Residue |
| D | PHE49 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q9Z4Z5 |
| Chain | Residue | Details |
| A | HIS176 | |
| D | HIS176 | |
| D | GLU178 | |
| D | HIS312 | |
| A | GLU178 | |
| A | HIS312 | |
| B | HIS176 | |
| B | GLU178 | |
| B | HIS312 | |
| C | HIS176 | |
| C | GLU178 | |
| C | HIS312 |
