Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | binding site for residue C2K A 301 |
| Chain | Residue |
| A | ARG8 |
| A | LEU45 |
| A | PHE61 |
| A | GLY64 |
| A | GLY65 |
| A | GLY66 |
| A | LEU67 |
| A | MET68 |
| A | ASN70 |
| A | ALA138 |
| A | LEU160 |
| A | GLU9 |
| A | ASP161 |
| A | HIS162 |
| A | EDO307 |
| A | HOH458 |
| A | VAL13 |
| A | PRO15 |
| A | GLN19 |
| A | GLY23 |
| A | SER24 |
| A | CSX25 |
| A | TRP26 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | GLY42 |
| A | ASN43 |
| A | PRO44 |
| A | ASN73 |
| A | ASN77 |
| A | HOH467 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 304 |
| Chain | Residue |
| A | THR58 |
| A | TRP74 |
| A | SER78 |
| A | HOH418 |
| B | THR153 |
| B | SER154 |
| B | EDO301 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 305 |
| Chain | Residue |
| A | ARG195 |
| A | HOH421 |
| A | HOH531 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 306 |
| Chain | Residue |
| A | SER78 |
| A | ASN79 |
| A | GLY80 |
| A | HOH445 |
| A | HOH503 |
| B | THR142 |
| B | THR156 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 307 |
| Chain | Residue |
| A | VAL13 |
| A | THR14 |
| A | PRO15 |
| A | C2K301 |
| A | HOH401 |
| A | HOH408 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 301 |
| Chain | Residue |
| A | EDO304 |
| B | GLY149 |
| B | HOH485 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 302 |
| Chain | Residue |
| B | GLY80 |
| B | ASN82 |
| B | ALA111 |
| B | ILE112 |
| B | HOH404 |
| B | HOH435 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 303 |
| Chain | Residue |
| B | PRO44 |
| B | ILE59 |
| B | ASN73 |
| B | TRP74 |
| B | ASN77 |
| B | SER78 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 304 |
| Chain | Residue |
| A | GLU97 |
| B | SER55 |
| B | ASP57 |
| B | ASP60 |
| B | GLN98 |
| site_id | AD2 |
| Number of Residues | 24 |
| Details | binding site for residue C2K B 305 |
| Chain | Residue |
| B | ARG8 |
| B | GLU9 |
| B | VAL13 |
| B | PRO15 |
| B | GLN19 |
| B | GLY23 |
| B | SER24 |
| B | CSX25 |
| B | TRP26 |
| B | LEU45 |
| B | PHE61 |
| B | GLY64 |
| B | GLY65 |
| B | GLY66 |
| B | LEU67 |
| B | MET68 |
| B | ASN70 |
| B | ALA138 |
| B | LEU160 |
| B | ASP161 |
| B | EDO312 |
| B | HOH401 |
| B | HOH463 |
| B | HOH526 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 306 |
| Chain | Residue |
| B | GLY20 |
| B | TRP184 |
| B | HOH421 |
| A | ASN186 |
| A | MET187 |
| B | ASP18 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 307 |
| Chain | Residue |
| B | TRP38 |
| B | ALA110 |
| B | EDO310 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 308 |
| Chain | Residue |
| A | ASP18 |
| A | GLY20 |
| A | GLY94 |
| B | VAL16 |
| B | SER185 |
| B | ASN186 |
| B | HOH426 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 309 |
| Chain | Residue |
| A | PRO119 |
| A | GLN120 |
| site_id | AD7 |
| Number of Residues | 9 |
| Details | binding site for residue EDO B 310 |
| Chain | Residue |
| B | TRP38 |
| B | VAL214 |
| B | GLY215 |
| B | GLY216 |
| B | PRO217 |
| B | EDO307 |
| B | HOH405 |
| B | HOH419 |
| B | HOH448 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 311 |
| Chain | Residue |
| B | ALA141 |
| B | ASP161 |
| B | HIS162 |
| B | HOH412 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 312 |
| Chain | Residue |
| B | ARG8 |
| B | VAL13 |
| B | THR14 |
| B | C2K305 |
| B | HOH402 |
| B | HOH409 |
Functional Information from PROSITE/UniProt
| site_id | PS00139 |
| Number of Residues | 12 |
| Details | THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QGqCGSCWAfST |
| Chain | Residue | Details |
| A | GLN19-THR30 | |
| site_id | PS00639 |
| Number of Residues | 11 |
| Details | THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. LDHGVLLVGYN |
| Chain | Residue | Details |
| A | LEU160-ASN170 | |
| site_id | PS00640 |
| Number of Residues | 20 |
| Details | THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. YWIiKNSWsnmWGedGYIrI |
| Chain | Residue | Details |
| A | TYR177-ILE196 | |
