6EVE

Structure of R175A S. cerevisiae Fdc1 with prFMN in the iminium form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0016829	molecular_function	lyase activity
A	0016831	molecular_function	carboxy-lyase activity
A	0033494	biological_process	ferulate metabolic process
A	0042537	biological_process	benzene-containing compound metabolic process
A	0046281	biological_process	cinnamic acid catabolic process
A	0046395	biological_process	carboxylic acid catabolic process
A	0046872	molecular_function	metal ion binding
A	0120254	biological_process	olefinic compound metabolic process
A	1901067	biological_process	ferulate catabolic process
B	0005737	cellular_component	cytoplasm
B	0016829	molecular_function	lyase activity
B	0016831	molecular_function	carboxy-lyase activity
B	0033494	biological_process	ferulate metabolic process
B	0042537	biological_process	benzene-containing compound metabolic process
B	0046281	biological_process	cinnamic acid catabolic process
B	0046395	biological_process	carboxylic acid catabolic process
B	0046872	molecular_function	metal ion binding
B	0120254	biological_process	olefinic compound metabolic process
B	1901067	biological_process	ferulate catabolic process
C	0005737	cellular_component	cytoplasm
C	0016829	molecular_function	lyase activity
C	0016831	molecular_function	carboxy-lyase activity
C	0033494	biological_process	ferulate metabolic process
C	0042537	biological_process	benzene-containing compound metabolic process
C	0046281	biological_process	cinnamic acid catabolic process
C	0046395	biological_process	carboxylic acid catabolic process
C	0046872	molecular_function	metal ion binding
C	0120254	biological_process	olefinic compound metabolic process
C	1901067	biological_process	ferulate catabolic process
D	0005737	cellular_component	cytoplasm
D	0016829	molecular_function	lyase activity
D	0016831	molecular_function	carboxy-lyase activity
D	0033494	biological_process	ferulate metabolic process
D	0042537	biological_process	benzene-containing compound metabolic process
D	0046281	biological_process	cinnamic acid catabolic process
D	0046395	biological_process	carboxylic acid catabolic process
D	0046872	molecular_function	metal ion binding
D	0120254	biological_process	olefinic compound metabolic process
D	1901067	biological_process	ferulate catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	23
Details	binding site for residue 4LU A 601

Chain	Residue
A	THR155
A	SER227
A	MET228
A	PRO229
A	GLU236
A	SER317
A	PRO319
A	ILE330
A	LYS394
A	MN602
A	K603
A	ASN170
A	HOH734
A	HOH780
A	HOH834
A	HOH897
A	SER172
A	ILE173
A	ALA174
A	ALA175
A	GLN192
A	HIS193
A	SER226

---

site_id	AC2
Number of Residues	6
Details	binding site for residue MN A 602

Chain	Residue
A	ASN170
A	HIS193
A	GLU236
A	4LU601
A	HOH780
A	HOH859

---

site_id	AC3
Number of Residues	6
Details	binding site for residue K A 603

Chain	Residue
A	TRP171
A	VAL225
A	SER226
A	MET228
A	GLU236
A	4LU601

---

site_id	AC4
Number of Residues	23
Details	binding site for residue 4LU B 601

Chain	Residue
B	THR155
B	ASN170
B	SER172
B	ILE173
B	ALA174
B	ALA175
B	GLN192
B	HIS193
B	SER226
B	SER227
B	MET228
B	PRO229
B	GLU236
B	PRO319
B	ILE330
B	LYS394
B	MN602
B	K603
B	HOH717
B	HOH754
B	HOH808
B	HOH842
B	HOH883

---

site_id	AC5
Number of Residues	6
Details	binding site for residue MN B 602

Chain	Residue
B	ASN170
B	HIS193
B	GLU236
B	4LU601
B	HOH717
B	HOH846

---

site_id	AC6
Number of Residues	6
Details	binding site for residue K B 603

Chain	Residue
B	TRP171
B	VAL225
B	SER226
B	MET228
B	GLU236
B	4LU601

---

site_id	AC7
Number of Residues	25
Details	binding site for residue 4LU C 601

Chain	Residue
C	THR155
C	ASN170
C	SER172
C	ILE173
C	ALA174
C	ALA175
C	GLN192
C	HIS193
C	SER226
C	SER227
C	MET228
C	PRO229
C	GLU236
C	SER317
C	PRO319
C	ILE330
C	LYS394
C	MN602
C	K603
C	HOH722
C	HOH772
C	HOH781
C	HOH868
C	HOH925
C	HOH943

---

site_id	AC8
Number of Residues	6
Details	binding site for residue MN C 602

Chain	Residue
C	HOH722
C	HOH906
C	ASN170
C	HIS193
C	GLU236
C	4LU601

---

site_id	AC9
Number of Residues	6
Details	binding site for residue K C 603

Chain	Residue
C	TRP171
C	VAL225
C	SER226
C	MET228
C	GLU236
C	4LU601

---

site_id	AD1
Number of Residues	23
Details	binding site for residue 4LU D 601

Chain	Residue
D	THR155
D	ASN170
D	SER172
D	ILE173
D	ALA174
D	ALA175
D	GLN192
D	HIS193
D	SER226
D	SER227
D	MET228
D	PRO229
D	GLU236
D	SER317
D	PRO319
D	ILE330
D	LYS394
D	MN602
D	MN603
D	HOH719
D	HOH737
D	HOH863
D	HOH878

---

site_id	AD2
Number of Residues	6
Details	binding site for residue MN D 602

Chain	Residue
D	ASN170
D	HIS193
D	GLU236
D	4LU601
D	HOH737
D	HOH894

---

site_id	AD3
Number of Residues	6
Details	binding site for residue MN D 603

Chain	Residue
D	TRP171
D	VAL225
D	SER226
D	MET228
D	GLU236
D	4LU601

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"A2QHE5","evidenceCode":"ECO:0000250"},{"source":"HAMAP-Rule","id":"MF_03196","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"25862228","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	40
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_03196","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"26083754","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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