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6EU9

Crystal structure of Platynereis dumerilii RAR ligand-binding domain in complex with all-trans retinoic acid

Functional Information from GO Data
ChainGOidnamespacecontents
A0000978molecular_functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
A0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0005634cellular_componentnucleus
A0005667cellular_componenttranscription regulator complex
A0006355biological_processregulation of DNA-templated transcription
A0006357biological_processregulation of transcription by RNA polymerase II
A0035259molecular_functionnuclear glucocorticoid receptor binding
A0048384biological_processretinoic acid receptor signaling pathway
A0071376biological_processcellular response to corticotropin-releasing hormone stimulus
B0000978molecular_functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
B0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
B0003677molecular_functionDNA binding
B0004879molecular_functionnuclear receptor activity
B0005634cellular_componentnucleus
B0005667cellular_componenttranscription regulator complex
B0006355biological_processregulation of DNA-templated transcription
B0006357biological_processregulation of transcription by RNA polymerase II
B0035259molecular_functionnuclear glucocorticoid receptor binding
B0048384biological_processretinoic acid receptor signaling pathway
B0071376biological_processcellular response to corticotropin-releasing hormone stimulus
C0000978molecular_functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
C0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
C0003677molecular_functionDNA binding
C0004879molecular_functionnuclear receptor activity
C0005634cellular_componentnucleus
C0005667cellular_componenttranscription regulator complex
C0006355biological_processregulation of DNA-templated transcription
C0006357biological_processregulation of transcription by RNA polymerase II
C0035259molecular_functionnuclear glucocorticoid receptor binding
C0048384biological_processretinoic acid receptor signaling pathway
C0071376biological_processcellular response to corticotropin-releasing hormone stimulus
D0000978molecular_functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
D0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
D0003677molecular_functionDNA binding
D0004879molecular_functionnuclear receptor activity
D0005634cellular_componentnucleus
D0005667cellular_componenttranscription regulator complex
D0006355biological_processregulation of DNA-templated transcription
D0006357biological_processregulation of transcription by RNA polymerase II
D0035259molecular_functionnuclear glucocorticoid receptor binding
D0048384biological_processretinoic acid receptor signaling pathway
D0071376biological_processcellular response to corticotropin-releasing hormone stimulus
Functional Information from PDB Data
site_idAC1
Number of Residues7
Detailsbinding site for residue REA B 601
ChainResidue
BARG355
BVAL356
BPHE414
BGLN424
BGLY428
BGLY429
BPHE430

site_idAC2
Number of Residues6
Detailsbinding site for residue REA D 601
ChainResidue
DPHE414
DGLY428
DGLY429
DPHE430
DVAL356
DLEU394

site_idAC3
Number of Residues5
Detailsbinding site for Ligand ASP D 336 bound to THR D 333
ChainResidue
DLEU332
DTHR333
DASP334
DASP335
DLYS337

site_idAC4
Number of Residues5
Detailsbinding site for Ligand ASP D 336 bound to THR D 333
ChainResidue
DLEU332
DTHR333
DASP334
DASP335
DLYS337

site_idAC5
Number of Residues5
Detailsbinding site for Ligand ASP D 336 bound to THR D 333
ChainResidue
DLEU332
DTHR333
DASP334
DASP335
DLYS337

site_idAC6
Number of Residues8
Detailsbinding site for Ligand ILE D 386 bound to THR D 382
ChainResidue
DTHR382
DASN383
DASP384
DGLN385
DTHR387
DLEU388
DLEU389
DLYS390

site_idAC7
Number of Residues12
Detailsbinding site for Di-peptide GLN D 422 and GLU D 426
ChainResidue
DASP410
DLEU420
DTHR421
DGLN423
DGLN424
DLEU425
DVAL427
DGLY428
DGLY431
DTHR434
DPHE438
DARG442

site_idAC8
Number of Residues8
Detailsbinding site for Di-peptide GLN D 423 and GLU D 426
ChainResidue
DASP410
DTHR421
DGLN422
DGLN424
DLEU425
DVAL427
DGLY428
DGLY431

site_idAC9
Number of Residues8
Detailsbinding site for Di-peptide GLN D 423 and GLU D 426
ChainResidue
DASP410
DTHR421
DGLN422
DGLN424
DLEU425
DVAL427
DGLY428
DGLY431

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PDB entries from 2024-10-30

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