6EU0

RNA Polymerase III open pre-initiation complex (OC-PIC)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000428	cellular_component	DNA-directed RNA polymerase complex
A	0003677	molecular_function	DNA binding
A	0003899	molecular_function	DNA-directed RNA polymerase activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005666	cellular_component	RNA polymerase III complex
A	0006351	biological_process	DNA-templated transcription
A	0006352	biological_process	DNA-templated transcription initiation
A	0006383	biological_process	transcription by RNA polymerase III
A	0006384	biological_process	transcription initiation at RNA polymerase III promoter
A	0006386	biological_process	termination of RNA polymerase III transcription
A	0008270	molecular_function	zinc ion binding
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0034062	molecular_function	5'-3' RNA polymerase activity
A	0042797	biological_process	tRNA transcription by RNA polymerase III
A	0046872	molecular_function	metal ion binding
B	0000428	cellular_component	DNA-directed RNA polymerase complex
B	0003677	molecular_function	DNA binding
B	0003899	molecular_function	DNA-directed RNA polymerase activity
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005666	cellular_component	RNA polymerase III complex
B	0006351	biological_process	DNA-templated transcription
B	0006352	biological_process	DNA-templated transcription initiation
B	0006383	biological_process	transcription by RNA polymerase III
B	0006384	biological_process	transcription initiation at RNA polymerase III promoter
B	0006386	biological_process	termination of RNA polymerase III transcription
B	0008270	molecular_function	zinc ion binding
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0032549	molecular_function	ribonucleoside binding
B	0034062	molecular_function	5'-3' RNA polymerase activity
B	0042797	biological_process	tRNA transcription by RNA polymerase III
B	0046872	molecular_function	metal ion binding
C	0000428	cellular_component	DNA-directed RNA polymerase complex
C	0003677	molecular_function	DNA binding
C	0003899	molecular_function	DNA-directed RNA polymerase activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005666	cellular_component	RNA polymerase III complex
C	0005730	cellular_component	nucleolus
C	0005736	cellular_component	RNA polymerase I complex
C	0006351	biological_process	DNA-templated transcription
C	0006360	biological_process	transcription by RNA polymerase I
C	0006361	biological_process	transcription initiation at RNA polymerase I promoter
C	0006362	biological_process	transcription elongation by RNA polymerase I
C	0006363	biological_process	termination of RNA polymerase I transcription
C	0006383	biological_process	transcription by RNA polymerase III
C	0006384	biological_process	transcription initiation at RNA polymerase III promoter
C	0006386	biological_process	termination of RNA polymerase III transcription
C	0042254	biological_process	ribosome biogenesis
C	0042790	biological_process	nucleolar large rRNA transcription by RNA polymerase I
C	0042797	biological_process	tRNA transcription by RNA polymerase III
C	0046983	molecular_function	protein dimerization activity
D	0000166	molecular_function	nucleotide binding
D	0000428	cellular_component	DNA-directed RNA polymerase complex
D	0003899	molecular_function	DNA-directed RNA polymerase activity
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005666	cellular_component	RNA polymerase III complex
D	0005829	cellular_component	cytosol
D	0006352	biological_process	DNA-templated transcription initiation
D	0006383	biological_process	transcription by RNA polymerase III
D	0006384	biological_process	transcription initiation at RNA polymerase III promoter
D	0006386	biological_process	termination of RNA polymerase III transcription
D	0030880	cellular_component	RNA polymerase complex
D	0042797	biological_process	tRNA transcription by RNA polymerase III
E	0000428	cellular_component	DNA-directed RNA polymerase complex
E	0001172	biological_process	RNA-templated transcription
E	0003677	molecular_function	DNA binding
E	0003899	molecular_function	DNA-directed RNA polymerase activity
E	0003968	molecular_function	RNA-directed RNA polymerase activity
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005665	cellular_component	RNA polymerase II, core complex
E	0005666	cellular_component	RNA polymerase III complex
E	0005736	cellular_component	RNA polymerase I complex
E	0006351	biological_process	DNA-templated transcription
E	0006360	biological_process	transcription by RNA polymerase I
E	0006361	biological_process	transcription initiation at RNA polymerase I promoter
E	0006362	biological_process	transcription elongation by RNA polymerase I
E	0006363	biological_process	termination of RNA polymerase I transcription
E	0006366	biological_process	transcription by RNA polymerase II
E	0006367	biological_process	transcription initiation at RNA polymerase II promoter
E	0006368	biological_process	transcription elongation by RNA polymerase II
E	0006383	biological_process	transcription by RNA polymerase III
E	0006384	biological_process	transcription initiation at RNA polymerase III promoter
E	0006386	biological_process	termination of RNA polymerase III transcription
E	0042254	biological_process	ribosome biogenesis
E	0042790	biological_process	nucleolar large rRNA transcription by RNA polymerase I
E	0042797	biological_process	tRNA transcription by RNA polymerase III
F	0000428	cellular_component	DNA-directed RNA polymerase complex
F	0001172	biological_process	RNA-templated transcription
F	0003677	molecular_function	DNA binding
F	0003899	molecular_function	DNA-directed RNA polymerase activity
F	0003968	molecular_function	RNA-directed RNA polymerase activity
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005665	cellular_component	RNA polymerase II, core complex
F	0005666	cellular_component	RNA polymerase III complex
F	0005736	cellular_component	RNA polymerase I complex
F	0005737	cellular_component	cytoplasm
F	0006351	biological_process	DNA-templated transcription
F	0006360	biological_process	transcription by RNA polymerase I
F	0006361	biological_process	transcription initiation at RNA polymerase I promoter
F	0006362	biological_process	transcription elongation by RNA polymerase I
F	0006363	biological_process	termination of RNA polymerase I transcription
F	0006366	biological_process	transcription by RNA polymerase II
F	0006367	biological_process	transcription initiation at RNA polymerase II promoter
F	0006368	biological_process	transcription elongation by RNA polymerase II
F	0006383	biological_process	transcription by RNA polymerase III
F	0006384	biological_process	transcription initiation at RNA polymerase III promoter
F	0006386	biological_process	termination of RNA polymerase III transcription
F	0042254	biological_process	ribosome biogenesis
F	0042790	biological_process	nucleolar large rRNA transcription by RNA polymerase I
F	0042797	biological_process	tRNA transcription by RNA polymerase III
G	0000428	cellular_component	DNA-directed RNA polymerase complex
G	0003677	molecular_function	DNA binding
G	0003899	molecular_function	DNA-directed RNA polymerase activity
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005666	cellular_component	RNA polymerase III complex
G	0006351	biological_process	DNA-templated transcription
G	0006352	biological_process	DNA-templated transcription initiation
G	0006383	biological_process	transcription by RNA polymerase III
G	0006384	biological_process	transcription initiation at RNA polymerase III promoter
G	0006386	biological_process	termination of RNA polymerase III transcription
G	0042797	biological_process	tRNA transcription by RNA polymerase III
H	0000428	cellular_component	DNA-directed RNA polymerase complex
H	0001172	biological_process	RNA-templated transcription
H	0003677	molecular_function	DNA binding
H	0003899	molecular_function	DNA-directed RNA polymerase activity
H	0003968	molecular_function	RNA-directed RNA polymerase activity
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005665	cellular_component	RNA polymerase II, core complex
H	0005666	cellular_component	RNA polymerase III complex
H	0005736	cellular_component	RNA polymerase I complex
H	0006351	biological_process	DNA-templated transcription
H	0006360	biological_process	transcription by RNA polymerase I
H	0006361	biological_process	transcription initiation at RNA polymerase I promoter
H	0006362	biological_process	transcription elongation by RNA polymerase I
H	0006363	biological_process	termination of RNA polymerase I transcription
H	0006366	biological_process	transcription by RNA polymerase II
H	0006367	biological_process	transcription initiation at RNA polymerase II promoter
H	0006368	biological_process	transcription elongation by RNA polymerase II
H	0006383	biological_process	transcription by RNA polymerase III
H	0006384	biological_process	transcription initiation at RNA polymerase III promoter
H	0006386	biological_process	termination of RNA polymerase III transcription
H	0042254	biological_process	ribosome biogenesis
H	0042790	biological_process	nucleolar large rRNA transcription by RNA polymerase I
H	0042797	biological_process	tRNA transcription by RNA polymerase III
I	0000428	cellular_component	DNA-directed RNA polymerase complex
I	0003676	molecular_function	nucleic acid binding
I	0003899	molecular_function	DNA-directed RNA polymerase activity
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005666	cellular_component	RNA polymerase III complex
I	0005730	cellular_component	nucleolus
I	0006351	biological_process	DNA-templated transcription
I	0006383	biological_process	transcription by RNA polymerase III
I	0006384	biological_process	transcription initiation at RNA polymerase III promoter
I	0006386	biological_process	termination of RNA polymerase III transcription
I	0008270	molecular_function	zinc ion binding
I	0042797	biological_process	tRNA transcription by RNA polymerase III
I	0046872	molecular_function	metal ion binding
J	0000428	cellular_component	DNA-directed RNA polymerase complex
J	0001172	biological_process	RNA-templated transcription
J	0003677	molecular_function	DNA binding
J	0003899	molecular_function	DNA-directed RNA polymerase activity
J	0003968	molecular_function	RNA-directed RNA polymerase activity
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005665	cellular_component	RNA polymerase II, core complex
J	0005666	cellular_component	RNA polymerase III complex
J	0005730	cellular_component	nucleolus
J	0005736	cellular_component	RNA polymerase I complex
J	0006351	biological_process	DNA-templated transcription
J	0006360	biological_process	transcription by RNA polymerase I
J	0006361	biological_process	transcription initiation at RNA polymerase I promoter
J	0006362	biological_process	transcription elongation by RNA polymerase I
J	0006363	biological_process	termination of RNA polymerase I transcription
J	0006366	biological_process	transcription by RNA polymerase II
J	0006367	biological_process	transcription initiation at RNA polymerase II promoter
J	0006368	biological_process	transcription elongation by RNA polymerase II
J	0006383	biological_process	transcription by RNA polymerase III
J	0006384	biological_process	transcription initiation at RNA polymerase III promoter
J	0006386	biological_process	termination of RNA polymerase III transcription
J	0008270	molecular_function	zinc ion binding
J	0042254	biological_process	ribosome biogenesis
J	0042790	biological_process	nucleolar large rRNA transcription by RNA polymerase I
J	0042797	biological_process	tRNA transcription by RNA polymerase III
J	0046872	molecular_function	metal ion binding
K	0000428	cellular_component	DNA-directed RNA polymerase complex
K	0003677	molecular_function	DNA binding
K	0003899	molecular_function	DNA-directed RNA polymerase activity
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005666	cellular_component	RNA polymerase III complex
K	0005730	cellular_component	nucleolus
K	0005736	cellular_component	RNA polymerase I complex
K	0006351	biological_process	DNA-templated transcription
K	0006360	biological_process	transcription by RNA polymerase I
K	0006361	biological_process	transcription initiation at RNA polymerase I promoter
K	0006362	biological_process	transcription elongation by RNA polymerase I
K	0006363	biological_process	termination of RNA polymerase I transcription
K	0006383	biological_process	transcription by RNA polymerase III
K	0006384	biological_process	transcription initiation at RNA polymerase III promoter
K	0006386	biological_process	termination of RNA polymerase III transcription
K	0042254	biological_process	ribosome biogenesis
K	0042790	biological_process	nucleolar large rRNA transcription by RNA polymerase I
K	0042797	biological_process	tRNA transcription by RNA polymerase III
K	0046983	molecular_function	protein dimerization activity
K	0055029	cellular_component	nuclear DNA-directed RNA polymerase complex
L	0000428	cellular_component	DNA-directed RNA polymerase complex
L	0001172	biological_process	RNA-templated transcription
L	0003677	molecular_function	DNA binding
L	0003899	molecular_function	DNA-directed RNA polymerase activity
L	0003968	molecular_function	RNA-directed RNA polymerase activity
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005665	cellular_component	RNA polymerase II, core complex
L	0005666	cellular_component	RNA polymerase III complex
L	0005730	cellular_component	nucleolus
L	0005736	cellular_component	RNA polymerase I complex
L	0005737	cellular_component	cytoplasm
L	0005777	cellular_component	peroxisome
L	0006351	biological_process	DNA-templated transcription
L	0006360	biological_process	transcription by RNA polymerase I
L	0006361	biological_process	transcription initiation at RNA polymerase I promoter
L	0006362	biological_process	transcription elongation by RNA polymerase I
L	0006363	biological_process	termination of RNA polymerase I transcription
L	0006366	biological_process	transcription by RNA polymerase II
L	0006367	biological_process	transcription initiation at RNA polymerase II promoter
L	0006368	biological_process	transcription elongation by RNA polymerase II
L	0006383	biological_process	transcription by RNA polymerase III
L	0006384	biological_process	transcription initiation at RNA polymerase III promoter
L	0006386	biological_process	termination of RNA polymerase III transcription
L	0008270	molecular_function	zinc ion binding
L	0042254	biological_process	ribosome biogenesis
L	0042790	biological_process	nucleolar large rRNA transcription by RNA polymerase I
L	0042797	biological_process	tRNA transcription by RNA polymerase III
L	0046872	molecular_function	metal ion binding
M	0000428	cellular_component	DNA-directed RNA polymerase complex
M	0003899	molecular_function	DNA-directed RNA polymerase activity
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005666	cellular_component	RNA polymerase III complex
M	0006351	biological_process	DNA-templated transcription
M	0006383	biological_process	transcription by RNA polymerase III
M	0006384	biological_process	transcription initiation at RNA polymerase III promoter
M	0006386	biological_process	termination of RNA polymerase III transcription
M	0042797	biological_process	tRNA transcription by RNA polymerase III
N	0000428	cellular_component	DNA-directed RNA polymerase complex
N	0003677	molecular_function	DNA binding
N	0003899	molecular_function	DNA-directed RNA polymerase activity
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0005654	cellular_component	nucleoplasm
N	0005666	cellular_component	RNA polymerase III complex
N	0006383	biological_process	transcription by RNA polymerase III
N	0006384	biological_process	transcription initiation at RNA polymerase III promoter
N	0006386	biological_process	termination of RNA polymerase III transcription
N	0042797	biological_process	tRNA transcription by RNA polymerase III
O	0000428	cellular_component	DNA-directed RNA polymerase complex
O	0003677	molecular_function	DNA binding
O	0003697	molecular_function	single-stranded DNA binding
O	0003899	molecular_function	DNA-directed RNA polymerase activity
O	0005515	molecular_function	protein binding
O	0005634	cellular_component	nucleus
O	0005654	cellular_component	nucleoplasm
O	0005666	cellular_component	RNA polymerase III complex
O	0005737	cellular_component	cytoplasm
O	0006351	biological_process	DNA-templated transcription
O	0006383	biological_process	transcription by RNA polymerase III
O	0006384	biological_process	transcription initiation at RNA polymerase III promoter
O	0006386	biological_process	termination of RNA polymerase III transcription
O	0042797	biological_process	tRNA transcription by RNA polymerase III
P	0000428	cellular_component	DNA-directed RNA polymerase complex
P	0003899	molecular_function	DNA-directed RNA polymerase activity
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005654	cellular_component	nucleoplasm
P	0005666	cellular_component	RNA polymerase III complex
P	0005737	cellular_component	cytoplasm
P	0005739	cellular_component	mitochondrion
P	0006383	biological_process	transcription by RNA polymerase III
P	0006384	biological_process	transcription initiation at RNA polymerase III promoter
P	0006386	biological_process	termination of RNA polymerase III transcription
P	0042797	biological_process	tRNA transcription by RNA polymerase III
Q	0000428	cellular_component	DNA-directed RNA polymerase complex
Q	0003677	molecular_function	DNA binding
Q	0003899	molecular_function	DNA-directed RNA polymerase activity
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005654	cellular_component	nucleoplasm
Q	0005666	cellular_component	RNA polymerase III complex
Q	0006383	biological_process	transcription by RNA polymerase III
Q	0006384	biological_process	transcription initiation at RNA polymerase III promoter
Q	0006386	biological_process	termination of RNA polymerase III transcription
Q	0016740	molecular_function	transferase activity
Q	0016779	molecular_function	nucleotidyltransferase activity
Q	0042797	biological_process	tRNA transcription by RNA polymerase III
V	0000126	cellular_component	transcription factor TFIIIB complex
V	0000995	molecular_function	RNA polymerase III general transcription initiation factor activity
V	0001112	biological_process	DNA-templated transcription open complex formation
V	0001156	molecular_function	TFIIIC-class transcription factor complex binding
V	0005634	cellular_component	nucleus
V	0005654	cellular_component	nucleoplasm
V	0006355	biological_process	regulation of DNA-templated transcription
V	0006359	biological_process	regulation of transcription by RNA polymerase III
V	0006383	biological_process	transcription by RNA polymerase III
V	0070898	biological_process	RNA polymerase III preinitiation complex assembly
Y	0000126	cellular_component	transcription factor TFIIIB complex
Y	0000979	molecular_function	RNA polymerase II core promoter sequence-specific DNA binding
Y	0001016	molecular_function	RNA polymerase III transcription regulatory region sequence-specific DNA binding
Y	0001092	molecular_function	TFIIA-class transcription factor complex binding
Y	0001179	molecular_function	RNA polymerase I general transcription initiation factor binding
Y	0001188	biological_process	RNA polymerase I preinitiation complex assembly
Y	0003677	molecular_function	DNA binding
Y	0003682	molecular_function	chromatin binding
Y	0005515	molecular_function	protein binding
Y	0005634	cellular_component	nucleus
Y	0005654	cellular_component	nucleoplasm
Y	0005667	cellular_component	transcription regulator complex
Y	0005669	cellular_component	transcription factor TFIID complex
Y	0005672	cellular_component	transcription factor TFIIA complex
Y	0006352	biological_process	DNA-templated transcription initiation
Y	0006359	biological_process	regulation of transcription by RNA polymerase III
Y	0006367	biological_process	transcription initiation at RNA polymerase II promoter
Y	0008301	molecular_function	DNA binding, bending
Y	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
Y	0032991	cellular_component	protein-containing complex
Y	0042790	biological_process	nucleolar large rRNA transcription by RNA polymerase I
Y	0045892	biological_process	negative regulation of DNA-templated transcription
Y	0045944	biological_process	positive regulation of transcription by RNA polymerase II
Y	0051123	biological_process	RNA polymerase II preinitiation complex assembly
Y	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
Y	0070898	biological_process	RNA polymerase III preinitiation complex assembly
Y	0097718	molecular_function	disordered domain specific binding
Y	0140297	molecular_function	DNA-binding transcription factor binding
Z	0000126	cellular_component	transcription factor TFIIIB complex
Z	0000994	molecular_function	RNA polymerase III core binding
Z	0000995	molecular_function	RNA polymerase III general transcription initiation factor activity
Z	0001006	molecular_function	RNA polymerase III type 3 promoter sequence-specific DNA binding
Z	0001112	biological_process	DNA-templated transcription open complex formation
Z	0001156	molecular_function	TFIIIC-class transcription factor complex binding
Z	0003677	molecular_function	DNA binding
Z	0005515	molecular_function	protein binding
Z	0005634	cellular_component	nucleus
Z	0005654	cellular_component	nucleoplasm
Z	0006352	biological_process	DNA-templated transcription initiation
Z	0006359	biological_process	regulation of transcription by RNA polymerase III
Z	0006383	biological_process	transcription by RNA polymerase III
Z	0006384	biological_process	transcription initiation at RNA polymerase III promoter
Z	0008270	molecular_function	zinc ion binding
Z	0017025	molecular_function	TBP-class protein binding
Z	0046872	molecular_function	metal ion binding
Z	0070897	biological_process	transcription preinitiation complex assembly
Z	0070898	biological_process	RNA polymerase III preinitiation complex assembly
Z	0097550	cellular_component	transcription preinitiation complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue ZN A 2000

Chain	Residue
A	ALA68
A	THR69
A	CYS70
A	CYS77
A	HIS80

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 2001

Chain	Residue
A	CYS107
A	CYS110
A	CYS154
A	CYS157

---

site_id	AC3
Number of Residues	2
Details	binding site for residue MG A 2002

Chain	Residue
A	ASP511
A	ASP515

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN B 1201

Chain	Residue
B	CYS1098
B	CYS1107
B	THR1109
B	CYS1110

---

site_id	AC5
Number of Residues	3
Details	binding site for residue ZN I 201

Chain	Residue
I	CYS8
I	CYS26
I	CYS29

---

site_id	AC6
Number of Residues	4
Details	binding site for residue ZN J 101

Chain	Residue
J	CYS7
J	CYS10
J	CYS45
J	CYS46

---

site_id	AC7
Number of Residues	5
Details	binding site for residue ZN L 101

Chain	Residue
L	CYS31
L	GLU33
L	CYS34
L	SER35
L	CYS51

---

site_id	AC8
Number of Residues	5
Details	binding site for residue ZN Z 601

Chain	Residue
Z	CYS4
Z	CYS7
Z	CYS25
Z	LYS26
Z	CYS28

---

Functional Information from PROSITE/UniProt

site_id	PS00351
Number of Residues	50
Details	TFIID Transcription factor TFIID repeat signature. YnPkrFaaVImRirePKttaLIFaSGKMvvtGAKseddsklAsrkyariI

Chain	Residue	Details
Y	TYR94-ILE143
Y	TYR185-LEU234

---

site_id	PS00446
Number of Residues	41
Details	RNA_POL_D_30KD RNA polymerases D / 30 to 40 Kd subunits signature. NAFRRimisevpsvAaeyVyffnNtSviqDEvLAhRIGLVP

Chain	Residue	Details
C	ASN65-PRO105

---

site_id	PS00782
Number of Residues	16
Details	TFIIB Transcription factor TFIIB repeat signature. GRrsqNVIASCLYVAC

Chain	Residue	Details
Z	GLY119-CYS134
Z	GLY217-CYS232

---

site_id	PS01030
Number of Residues	26
Details	RNA_POL_M_15KD RNA polymerases M / 15 Kd subunits signature. FCPSCNNMLlitsgdsgvytla.CrsC

Chain	Residue	Details
I	PHE4-CYS29

---

site_id	PS01110
Number of Residues	14
Details	RNA_POL_H_23KD RNA polymerases H / 23 Kd subunits signature. HELVPKHirLssDE

Chain	Residue	Details
E	HIS147-GLU160

---

site_id	PS01111
Number of Residues	15
Details	RNA_POL_K_14KD RNA polymerases K / 14 to 18 Kd subunits signature. TkYErARiLGtRAlQ

Chain	Residue	Details
F	THR86-GLN100

---

site_id	PS01112
Number of Residues	10
Details	RNA_POL_N_8KD RNA polymerases N / 8 Kd subunits signature. IVPVrCFSCG

Chain	Residue	Details
J	ILE2-GLY11

---

site_id	PS01154
Number of Residues	32
Details	RNA_POL_L_13KD RNA polymerases L / 13 to 16 Kd subunits signature. IveEdHTLgNaLryvImknpdVefcgYsipHP

Chain	Residue	Details
K	ILE65-PRO96

---

site_id	PS01166
Number of Residues	13
Details	RNA_POL_BETA RNA polymerases beta chain signature. GdKFSSrHGQKGV

Chain	Residue	Details
B	GLY909-VAL921

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Region: {"description":"Bridging helix","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	14
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	15
Details	Zinc finger: {"description":"C4-type","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	42
Details	Region: {"description":"Leucine-zipper"}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	54
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	40
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17330950","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	23
Details	Region: {"description":"Non-specific ssDNA binding","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	24
Details	Zinc finger: {"description":"C4-type","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10145","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15537538","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1TWF","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"22106047","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	20
Details	Zinc finger: {"description":"C4-type"}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	4
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	51
Details	Domain: {"description":"SANT"}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	152
Details	Repeat: {"description":"1"}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	156
Details	Repeat: {"description":"2"}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	32
Details	Zinc finger: {"description":"TFIIB-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00469","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00469","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---