Functional Information from GO Data
| Chain | GOid | namespace | contents |
| R | 0003924 | molecular_function | GTPase activity |
| R | 0005525 | molecular_function | GTP binding |
| R | 0007165 | biological_process | signal transduction |
| R | 0016020 | cellular_component | membrane |
| S | 0005085 | molecular_function | guanyl-nucleotide exchange factor activity |
| S | 0007264 | biological_process | small GTPase-mediated signal transduction |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue GOL R 201 |
| Chain | Residue |
| R | ARG68 |
| R | HIS95 |
| R | GLN99 |
| R | HOH345 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue BPW S 1101 |
| Chain | Residue |
| S | MET878 |
| S | ASN879 |
| S | HIS905 |
| S | GLU906 |
| S | GLU909 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue BPW S 1102 |
| Chain | Residue |
| S | VAL883 |
| S | TYR884 |
| S | LEU886 |
| S | PHE890 |
Functional Information from PROSITE/UniProt
| site_id | PS00720 |
| Number of Residues | 34 |
| Details | RASGEF Ras Guanine-nucleotide exchange factors domain signature. VPFfGiyLtNIlkteegnpevlkrhgkel.................INFsK |
| Chain | Residue | Details |
| S | VAL927-LYS960 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| R | GLY10 | |
| R | VAL29 | |
| R | ALA59 | |
| R | ASN116 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylmethionine; in GTPase KRas; alternate => ECO:0000269|Ref.17 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylthreonine; in GTPase KRas, N-terminally processed => ECO:0000269|Ref.17 |
| Chain | Residue | Details |
| R | LYS104 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | CARBOHYD: (Microbial infection) O-linked (Glc) threonine; by P.sordellii toxin TcsL => ECO:0000269|PubMed:19744486 |
| Chain | Residue | Details |
| R | THR35 | |
