Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue EPZ B 501 |
| Chain | Residue |
| B | SER6 |
| B | VAL84 |
| B | SER87 |
| B | LYS115 |
| B | GLY134 |
| B | GLN135 |
| B | SER141 |
| B | LYS145 |
| B | ILE187 |
| B | HOH601 |
| B | HOH603 |
| B | ASN9 |
| B | HOH614 |
| B | HOH617 |
| B | ALA55 |
| B | ASP56 |
| B | LYS59 |
| B | ASN75 |
| B | HIS79 |
| B | ASN80 |
| B | ALA83 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 B 502 |
| Chain | Residue |
| A | TYR40 |
| B | ILE110 |
| B | GLY112 |
| B | SER113 |
| B | GLY114 |
| B | LYS115 |
| B | THR116 |
| B | ARG175 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 503 |
| Chain | Residue |
| B | ASN76 |
| B | SER184 |
| B | GLY269 |
| B | SER270 |
| B | HOH602 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 504 |
| Chain | Residue |
| B | ARG203 |
| B | LYS226 |
| B | PHE227 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 505 |
| Chain | Residue |
| B | GLN375 |
| B | SER390 |
| D | GLN375 |
| D | SER390 |
| site_id | AC6 |
| Number of Residues | 20 |
| Details | binding site for residue EPZ D 501 |
| Chain | Residue |
| D | SER6 |
| D | ASP7 |
| D | ASN9 |
| D | ALA55 |
| D | ASP56 |
| D | LYS59 |
| D | ASN75 |
| D | HIS79 |
| D | ASN80 |
| D | ALA83 |
| D | VAL84 |
| D | SER87 |
| D | LYS115 |
| D | GLY134 |
| D | GLN135 |
| D | SER141 |
| D | LYS145 |
| D | ILE187 |
| D | HOH603 |
| D | HOH612 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 D 502 |
| Chain | Residue |
| C | TYR40 |
| D | ILE110 |
| D | PRO111 |
| D | GLY112 |
| D | SER113 |
| D | GLY114 |
| D | LYS115 |
| D | THR116 |
| D | ARG175 |
| D | HOH604 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 D 503 |
| Chain | Residue |
| D | ASN76 |
| D | SER184 |
| D | GLY269 |
| D | SER270 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue FLC D 504 |
| Chain | Residue |
| D | ALA137 |
| D | ARG138 |
| D | PRO139 |
| D | GLN140 |
| D | ASN194 |
| D | ASP197 |
| D | GLN201 |
| site_id | AD1 |
| Number of Residues | 20 |
| Details | binding site for residue EPZ F 501 |
| Chain | Residue |
| F | ILE187 |
| F | HOH610 |
| F | HOH613 |
| F | SER6 |
| F | ASP7 |
| F | ASN9 |
| F | ALA55 |
| F | ASP56 |
| F | LYS59 |
| F | ASN75 |
| F | HIS79 |
| F | ASN80 |
| F | ALA83 |
| F | VAL84 |
| F | SER87 |
| F | LYS115 |
| F | GLY134 |
| F | GLN135 |
| F | SER141 |
| F | LYS145 |
| site_id | AD2 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 F 502 |
| Chain | Residue |
| E | TYR40 |
| F | ILE110 |
| F | PRO111 |
| F | GLY112 |
| F | SER113 |
| F | GLY114 |
| F | LYS115 |
| F | THR116 |
| F | ARG175 |
| F | HOH615 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 F 503 |
| Chain | Residue |
| F | ASN76 |
| F | SER184 |
| F | GLY269 |
| F | SER270 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue FLC F 504 |
| Chain | Residue |
| F | ALA137 |
| F | ARG138 |
| F | PRO139 |
| F | GLN140 |
| F | ASP197 |
| F | GLN201 |
| site_id | AD5 |
| Number of Residues | 21 |
| Details | binding site for residue EPZ H 501 |
| Chain | Residue |
| H | SER6 |
| H | ASP7 |
| H | ASN9 |
| H | ALA55 |
| H | ASP56 |
| H | LYS59 |
| H | ASN75 |
| H | HIS79 |
| H | ASN80 |
| H | ALA83 |
| H | VAL84 |
| H | SER87 |
| H | LYS115 |
| H | GLY134 |
| H | GLN135 |
| H | SER141 |
| H | LYS145 |
| H | ILE187 |
| H | HOH601 |
| H | HOH606 |
| H | HOH608 |
| site_id | AD6 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 H 502 |
| Chain | Residue |
| G | TYR40 |
| H | ILE110 |
| H | GLY112 |
| H | SER113 |
| H | GLY114 |
| H | LYS115 |
| H | THR116 |
| H | ARG175 |
| H | HOH611 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 H 503 |
| Chain | Residue |
| H | ASN76 |
| H | SER184 |
| H | GLY269 |
| H | SER270 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 H 504 |
| Chain | Residue |
| H | ARG203 |
| H | ASP225 |
| H | LYS226 |
| H | PHE227 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 H 505 |
| Chain | Residue |
| F | GLN375 |
| F | SER390 |
| H | GLN375 |
| H | SER390 |
