6EPB

Structure of Chitinase 42 from Trichoderma harzianum

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0005975	biological_process	carbohydrate metabolic process
A	0008061	molecular_function	chitin binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue ZN A 501

Chain	Residue
A	GLU171
A	ACT528
A	HOH601
A	HOH723
A	HOH844

---

site_id	AC2
Number of Residues	5
Details	binding site for residue ZN A 502

Chain	Residue
A	HOH862
A	ASP51
A	ASP226
A	HOH602
A	HOH781

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN A 503

Chain	Residue
A	HIS205
A	ASP232
A	ACT530
A	HOH853

---

site_id	AC4
Number of Residues	6
Details	binding site for residue ZN A 504

Chain	Residue
A	HIS395
A	HOH611
A	HOH725
A	HOH859
A	HOH861
A	HOH865

---

site_id	AC5
Number of Residues	4
Details	binding site for residue ZN A 505

Chain	Residue
A	HIS92
A	EDO517
A	HOH830
A	HOH856

---

site_id	AC6
Number of Residues	3
Details	binding site for residue ZN A 506

Chain	Residue
A	HIS205
A	HOH840
A	HOH860

---

site_id	AC7
Number of Residues	4
Details	binding site for residue ZN A 507

Chain	Residue
A	GLU316
A	ACT531
A	IMD532
A	HOH831

---

site_id	AC8
Number of Residues	5
Details	binding site for residue EDO A 508

Chain	Residue
A	SER41
A	LEU125
A	THR209
A	TYR233
A	ASN235

---

site_id	AC9
Number of Residues	6
Details	binding site for residue EDO A 509

Chain	Residue
A	SER142
A	THR177
A	GLN178
A	SER346
A	HOH609
A	HOH618

---

site_id	AD1
Number of Residues	3
Details	binding site for residue EDO A 510

Chain	Residue
A	ARG52
A	ASN53
A	HOH626

---

site_id	AD2
Number of Residues	7
Details	binding site for residue EDO A 511

Chain	Residue
A	ASP100
A	GLY102
A	THR103
A	ASN104
A	TYR106
A	EDO517
A	HOH773

---

site_id	AD3
Number of Residues	7
Details	binding site for residue EDO A 512

Chain	Residue
A	TYR93
A	ALA94
A	ASP95
A	GLN111
A	LYS114
A	ASN278
A	HOH826

---

site_id	AD4
Number of Residues	6
Details	binding site for residue EDO A 513

Chain	Residue
A	ASP77
A	ARG120
A	ALA145
A	ASN146
A	ASN149
A	LEU408

---

site_id	AD5
Number of Residues	6
Details	binding site for residue EDO A 514

Chain	Residue
A	SER134
A	THR135
A	PRO138
A	TRP170
A	TYR172
A	GLN178

---

site_id	AD6
Number of Residues	4
Details	binding site for residue EDO A 515

Chain	Residue
A	GLN75
A	ASP77
A	THR79
A	GLN405

---

site_id	AD7
Number of Residues	4
Details	binding site for residue EDO A 516

Chain	Residue
A	LEU422
A	EDO520
A	EDO522
A	HOH612

---

site_id	AD8
Number of Residues	5
Details	binding site for residue EDO A 517

Chain	Residue
A	HIS92
A	TYR106
A	ZN505
A	EDO511
A	HOH830

---

site_id	AD9
Number of Residues	6
Details	binding site for residue EDO A 518

Chain	Residue
A	SER62
A	VAL64
A	GLY121
A	ASP402
A	HOH789
A	HOH806

---

site_id	AE1
Number of Residues	1
Details	binding site for residue EDO A 519

Chain	Residue
A	LYS187

---

site_id	AE2
Number of Residues	5
Details	binding site for residue EDO A 520

Chain	Residue
A	ASN420
A	LEU422
A	ASN423
A	EDO516
A	HOH604

---

site_id	AE3
Number of Residues	6
Details	binding site for residue EDO A 521

Chain	Residue
A	SER134
A	THR135
A	ASN136
A	ASN73
A	LEU74
A	TRP133

---

site_id	AE4
Number of Residues	5
Details	binding site for residue EDO A 522

Chain	Residue
A	ASP95
A	LYS110
A	LYS114
A	EDO516
A	HOH606

---

site_id	AE5
Number of Residues	8
Details	binding site for residue EDO A 523

Chain	Residue
A	LYS327
A	ALA328
A	ALA330
A	ASN345
A	THR348
A	GLU350
A	HOH617
A	HOH704

---

site_id	AE6
Number of Residues	6
Details	binding site for residue EDO A 524

Chain	Residue
A	HIS92
A	ASP96
A	TRP98
A	GLY371
A	EDO525
A	HOH637

---

site_id	AE7
Number of Residues	6
Details	binding site for residue EDO A 525

Chain	Residue
A	HIS92
A	ASN284
A	EDO524
A	HOH637
A	HOH729
A	HOH799

---

site_id	AE8
Number of Residues	4
Details	binding site for residue EDO A 526

Chain	Residue
A	TRP98
A	ASN99
A	GLY102
A	HOH773

---

site_id	AE9
Number of Residues	4
Details	binding site for residue EDO A 527

Chain	Residue
A	TYR50
A	ASP51
A	ARG52
A	HOH719

---

site_id	AF1
Number of Residues	8
Details	binding site for residue ACT A 528

Chain	Residue
A	TYR43
A	ASP169
A	GLU171
A	MET237
A	TYR239
A	ZN501
A	HOH601
A	HOH623

---

site_id	AF2
Number of Residues	2
Details	binding site for residue ACT A 529

Chain	Residue
A	SER314
A	TRP315

---

site_id	AF3
Number of Residues	6
Details	binding site for residue ACT A 530

Chain	Residue
A	HIS205
A	GLN229
A	VAL230
A	ASP232
A	ZN503
A	HOH652

---

site_id	AF4
Number of Residues	8
Details	binding site for residue ACT A 531

Chain	Residue
A	THR45
A	TRP47
A	ARG52
A	GLU316
A	GLU379
A	ZN507
A	IMD532
A	HOH881

---

site_id	AF5
Number of Residues	6
Details	binding site for residue IMD A 532

Chain	Residue
A	TYR293
A	TRP378
A	ZN507
A	ACT531
A	HOH641
A	HOH647

---

Functional Information from PROSITE/UniProt

site_id	PS01095
Number of Residues	9
Details	GH18_1 Glycosyl hydrolases family 18 (GH18) active site signature. FDGIDIDwE

Chain	Residue	Details
A	PHE163-GLU171

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	363
Details	Domain: {"description":"GH18","evidences":[{"source":"PROSITE-ProRule","id":"PRU01258","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PROSITE-ProRule","id":"PRU01258","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01258","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---