6EP3

Lar controls the expression of the Listeria monocytogenes agr system and mediates virulence.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription
B	0000987	molecular_function	cis-regulatory region sequence-specific DNA binding
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue EDO A 301

Chain	Residue
A	TYR80
A	MET84
A	PHE130
A	HIS133
A	HIS134
A	MET160
A	HOH411

---

site_id	AC2
Number of Residues	2
Details	binding site for residue EDO A 302

Chain	Residue
A	ARG135
A	LYS154

---

site_id	AC3
Number of Residues	5
Details	binding site for residue EDO A 303

Chain	Residue
A	PHE90
A	ALA93
A	ALA94
A	ALA144
A	GLN149

---

site_id	AC4
Number of Residues	3
Details	binding site for residue SO4 A 304

Chain	Residue
A	ARG79
A	HOH403
A	HOH406

---

site_id	AC5
Number of Residues	3
Details	binding site for residue SO4 A 305

Chain	Residue
A	LYS109
A	ARG113
B	TYR122

---

site_id	AC6
Number of Residues	1
Details	binding site for residue SO4 A 306

Chain	Residue
A	ARG199

---

site_id	AC7
Number of Residues	3
Details	binding site for residue SO4 A 307

Chain	Residue
A	SER45
A	ARG48
B	ARG48

---

site_id	AC8
Number of Residues	2
Details	binding site for residue SO4 A 308

Chain	Residue
A	LYS194
B	LYS194

---

site_id	AC9
Number of Residues	3
Details	binding site for residue EPE A 309

Chain	Residue
A	SER172
A	VAL173
A	GLU174

---

site_id	AD1
Number of Residues	6
Details	binding site for residue EDO B 301

Chain	Residue
B	TYR80
B	PHE130
B	HIS133
B	HIS134
B	MET160
B	LEU209

---

site_id	AD2
Number of Residues	3
Details	binding site for residue EDO B 302

Chain	Residue
B	ARG135
B	LYS154
B	HOH428

---

site_id	AD3
Number of Residues	3
Details	binding site for residue EDO B 303

Chain	Residue
B	SER172
B	VAL173
B	GLU174

---

site_id	AD4
Number of Residues	3
Details	binding site for residue SO4 B 304

Chain	Residue
A	TYR122
B	LYS109
B	ARG113

---

site_id	AD5
Number of Residues	1
Details	binding site for residue SO4 B 305

Chain	Residue
B	ARG199

---

site_id	AD6
Number of Residues	2
Details	binding site for residue SO4 B 306

Chain	Residue
B	ARG79
B	HOH402

---

site_id	AD7
Number of Residues	5
Details	binding site for residue SO4 B 307

Chain	Residue
B	ALA99
B	HIS100
B	LYS181
B	LYS182
B	GLN185

---

site_id	AD8
Number of Residues	2
Details	binding site for residue SO4 B 308

Chain	Residue
A	ARG119
B	ARG119

---