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6EOS

DPP8 - Apo, space group 19

Functional Information from GO Data
ChainGOidnamespacecontents
A0004177molecular_functionaminopeptidase activity
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006508biological_processproteolysis
A0006915biological_processapoptotic process
A0006955biological_processimmune response
A0008233molecular_functionpeptidase activity
A0008236molecular_functionserine-type peptidase activity
A0008239molecular_functiondipeptidyl-peptidase activity
A0016787molecular_functionhydrolase activity
A0043069biological_processnegative regulation of programmed cell death
A0051604biological_processprotein maturation
A0140633biological_processCARD8 inflammasome complex assembly
A0141201biological_processpyroptotic cell death
A1904784biological_processNLRP1 inflammasome complex assembly
B0004177molecular_functionaminopeptidase activity
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006508biological_processproteolysis
B0006915biological_processapoptotic process
B0006955biological_processimmune response
B0008233molecular_functionpeptidase activity
B0008236molecular_functionserine-type peptidase activity
B0008239molecular_functiondipeptidyl-peptidase activity
B0016787molecular_functionhydrolase activity
B0043069biological_processnegative regulation of programmed cell death
B0051604biological_processprotein maturation
B0140633biological_processCARD8 inflammasome complex assembly
B0141201biological_processpyroptotic cell death
B1904784biological_processNLRP1 inflammasome complex assembly
C0004177molecular_functionaminopeptidase activity
C0005515molecular_functionprotein binding
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0006508biological_processproteolysis
C0006915biological_processapoptotic process
C0006955biological_processimmune response
C0008233molecular_functionpeptidase activity
C0008236molecular_functionserine-type peptidase activity
C0008239molecular_functiondipeptidyl-peptidase activity
C0016787molecular_functionhydrolase activity
C0043069biological_processnegative regulation of programmed cell death
C0051604biological_processprotein maturation
C0140633biological_processCARD8 inflammasome complex assembly
C0141201biological_processpyroptotic cell death
C1904784biological_processNLRP1 inflammasome complex assembly
D0004177molecular_functionaminopeptidase activity
D0005515molecular_functionprotein binding
D0005737cellular_componentcytoplasm
D0005829cellular_componentcytosol
D0006508biological_processproteolysis
D0006915biological_processapoptotic process
D0006955biological_processimmune response
D0008233molecular_functionpeptidase activity
D0008236molecular_functionserine-type peptidase activity
D0008239molecular_functiondipeptidyl-peptidase activity
D0016787molecular_functionhydrolase activity
D0043069biological_processnegative regulation of programmed cell death
D0051604biological_processprotein maturation
D0140633biological_processCARD8 inflammasome complex assembly
D0141201biological_processpyroptotic cell death
D1904784biological_processNLRP1 inflammasome complex assembly
E0004177molecular_functionaminopeptidase activity
E0005515molecular_functionprotein binding
E0005737cellular_componentcytoplasm
E0005829cellular_componentcytosol
E0006508biological_processproteolysis
E0006915biological_processapoptotic process
E0006955biological_processimmune response
E0008233molecular_functionpeptidase activity
E0008236molecular_functionserine-type peptidase activity
E0008239molecular_functiondipeptidyl-peptidase activity
E0016787molecular_functionhydrolase activity
E0043069biological_processnegative regulation of programmed cell death
E0051604biological_processprotein maturation
E0140633biological_processCARD8 inflammasome complex assembly
E0141201biological_processpyroptotic cell death
E1904784biological_processNLRP1 inflammasome complex assembly
F0004177molecular_functionaminopeptidase activity
F0005515molecular_functionprotein binding
F0005737cellular_componentcytoplasm
F0005829cellular_componentcytosol
F0006508biological_processproteolysis
F0006915biological_processapoptotic process
F0006955biological_processimmune response
F0008233molecular_functionpeptidase activity
F0008236molecular_functionserine-type peptidase activity
F0008239molecular_functiondipeptidyl-peptidase activity
F0016787molecular_functionhydrolase activity
F0043069biological_processnegative regulation of programmed cell death
F0051604biological_processprotein maturation
F0140633biological_processCARD8 inflammasome complex assembly
F0141201biological_processpyroptotic cell death
F1904784biological_processNLRP1 inflammasome complex assembly
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues18
DetailsACT_SITE: Charge relay system => ECO:0000305|PubMed:12534281, ECO:0000305|PubMed:29382749
ChainResidueDetails
ASER755
ESER755
EASP833
EHIS865
FSER755
FASP833
FHIS865
BSER755
BASP833
BHIS865
AASP833
AHIS865
CSER755
CASP833
CHIS865
DSER755
DASP833
DHIS865

237735

PDB entries from 2025-06-18

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