6EOD

Structure of Reductive Aminase from Aspergillus terreus in complex with NADPH

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000785	cellular_component	chromatin
A	0003677	molecular_function	DNA binding
A	0016491	molecular_function	oxidoreductase activity
A	0031491	molecular_function	nucleosome binding
A	0050661	molecular_function	NADP binding
A	0140673	biological_process	transcription elongation-coupled chromatin remodeling
B	0000166	molecular_function	nucleotide binding
B	0000785	cellular_component	chromatin
B	0003677	molecular_function	DNA binding
B	0016491	molecular_function	oxidoreductase activity
B	0031491	molecular_function	nucleosome binding
B	0050661	molecular_function	NADP binding
B	0140673	biological_process	transcription elongation-coupled chromatin remodeling
C	0000166	molecular_function	nucleotide binding
C	0000785	cellular_component	chromatin
C	0003677	molecular_function	DNA binding
C	0016491	molecular_function	oxidoreductase activity
C	0031491	molecular_function	nucleosome binding
C	0050661	molecular_function	NADP binding
C	0140673	biological_process	transcription elongation-coupled chromatin remodeling
D	0000166	molecular_function	nucleotide binding
D	0000785	cellular_component	chromatin
D	0003677	molecular_function	DNA binding
D	0016491	molecular_function	oxidoreductase activity
D	0031491	molecular_function	nucleosome binding
D	0050661	molecular_function	NADP binding
D	0140673	biological_process	transcription elongation-coupled chromatin remodeling
E	0000166	molecular_function	nucleotide binding
E	0000785	cellular_component	chromatin
E	0003677	molecular_function	DNA binding
E	0016491	molecular_function	oxidoreductase activity
E	0031491	molecular_function	nucleosome binding
E	0050661	molecular_function	NADP binding
E	0140673	biological_process	transcription elongation-coupled chromatin remodeling
F	0000166	molecular_function	nucleotide binding
F	0000785	cellular_component	chromatin
F	0003677	molecular_function	DNA binding
F	0016491	molecular_function	oxidoreductase activity
F	0031491	molecular_function	nucleosome binding
F	0050661	molecular_function	NADP binding
F	0140673	biological_process	transcription elongation-coupled chromatin remodeling
G	0000166	molecular_function	nucleotide binding
G	0000785	cellular_component	chromatin
G	0003677	molecular_function	DNA binding
G	0016491	molecular_function	oxidoreductase activity
G	0031491	molecular_function	nucleosome binding
G	0050661	molecular_function	NADP binding
G	0140673	biological_process	transcription elongation-coupled chromatin remodeling
H	0000166	molecular_function	nucleotide binding
H	0000785	cellular_component	chromatin
H	0003677	molecular_function	DNA binding
H	0016491	molecular_function	oxidoreductase activity
H	0031491	molecular_function	nucleosome binding
H	0050661	molecular_function	NADP binding
H	0140673	biological_process	transcription elongation-coupled chromatin remodeling

Functional Information from PDB Data

site_id	AC1
Number of Residues	27
Details	binding site for residue NAP A 301

Chain	Residue
A	LEU15
A	LEU71
A	LEU72
A	ALA76
A	GLN79
A	THR97
A	ASN98
A	ILE123
A	ALA125
A	PRO127
A	HOH408
A	GLY16
A	HOH417
A	HOH418
A	HOH464
A	HOH492
H	THR239
H	SER240
H	ASN241
H	MET244
A	ALA17
A	MET18
A	ASN37
A	ARG38
A	THR39
A	LYS42
A	CYS70

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site_id	AC2
Number of Residues	28
Details	binding site for residue NAP B 301

Chain	Residue
B	GLY14
B	LEU15
B	GLY16
B	ALA17
B	MET18
B	ASN37
B	ARG38
B	THR39
B	CYS70
B	LEU71
B	LEU72
B	ALA76
B	GLN79
B	THR97
B	ASN98
B	ILE123
B	ALA125
B	PRO127
B	HOH417
B	HOH423
B	HOH425
B	HOH447
B	HOH451
G	THR239
G	SER240
G	ASN241
G	MET244
G	HOH341

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site_id	AC3
Number of Residues	26
Details	binding site for residue NAP C 301

Chain	Residue
C	GLY14
C	LEU15
C	GLY16
C	ALA17
C	MET18
C	ASN37
C	ARG38
C	THR39
C	CYS70
C	LEU71
C	LEU72
C	ALA76
C	THR97
C	ASN98
C	ILE123
C	ALA125
C	PRO127
C	HOH405
C	HOH444
C	HOH445
C	HOH453
D	THR239
D	SER240
D	ASN241
D	MET244
D	HOH314

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