6ENI
Tryptophan Repressor TrpR from E.coli variant T44L S88Y with Indole-3-acetic acid as ligand
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0043565 | molecular_function | sequence-specific DNA binding |
| A | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0043565 | molecular_function | sequence-specific DNA binding |
| B | 0045892 | biological_process | negative regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue IAC A 201 |
| Chain | Residue |
| A | ARG54 |
| A | ARG84 |
| A | TYR88 |
| A | HOH368 |
| A | HOH410 |
| B | LEU41 |
| B | MET42 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 202 |
| Chain | Residue |
| A | HOH302 |
| A | HOH332 |
| A | HOH354 |
| A | HOH373 |
| B | ASN73 |
| B | GLU95 |
| A | PRO93 |
| A | VAL94 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue IAC B 201 |
| Chain | Residue |
| A | LEU41 |
| A | MET42 |
| B | ARG54 |
| B | ARG84 |
| B | TYR88 |
| B | HOH330 |
| B | HOH430 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 46 |
| Details | DNA binding: {} |
| Chain | Residue | Details |
