6EML

Cryo-EM structure of a late pre-40S ribosomal subunit from Saccharomyces cerevisiae

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
a	0000461	biological_process	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
a	0003735	molecular_function	structural constituent of ribosome
a	0005737	cellular_component	cytoplasm
a	0005829	cellular_component	cytosol
a	0005840	cellular_component	ribosome
a	0006364	biological_process	rRNA processing
a	0006412	biological_process	translation
a	0022627	cellular_component	cytosolic small ribosomal subunit
a	1990904	cellular_component	ribonucleoprotein complex
b	0002181	biological_process	cytoplasmic translation
b	0003735	molecular_function	structural constituent of ribosome
b	0005737	cellular_component	cytoplasm
b	0005829	cellular_component	cytosol
b	0005840	cellular_component	ribosome
b	0006412	biological_process	translation
b	0022627	cellular_component	cytosolic small ribosomal subunit
b	1990904	cellular_component	ribonucleoprotein complex
B	0000054	biological_process	ribosomal subunit export from nucleus
B	0002181	biological_process	cytoplasmic translation
B	0003723	molecular_function	RNA binding
B	0003729	molecular_function	mRNA binding
B	0003735	molecular_function	structural constituent of ribosome
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005840	cellular_component	ribosome
B	0006412	biological_process	translation
B	0006450	biological_process	regulation of translational fidelity
B	0015935	cellular_component	small ribosomal subunit
B	0019843	molecular_function	rRNA binding
B	0022627	cellular_component	cytosolic small ribosomal subunit
B	0030490	biological_process	maturation of SSU-rRNA
B	0030686	cellular_component	90S preribosome
B	1990904	cellular_component	ribonucleoprotein complex
c	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
c	0003735	molecular_function	structural constituent of ribosome
c	0005737	cellular_component	cytoplasm
c	0005829	cellular_component	cytosol
c	0005840	cellular_component	ribosome
c	0006412	biological_process	translation
c	0006450	biological_process	regulation of translational fidelity
c	0015935	cellular_component	small ribosomal subunit
c	0022627	cellular_component	cytosolic small ribosomal subunit
c	1990145	biological_process	maintenance of translational fidelity
c	1990904	cellular_component	ribonucleoprotein complex
C	0000028	biological_process	ribosomal small subunit assembly
C	0002181	biological_process	cytoplasmic translation
C	0003735	molecular_function	structural constituent of ribosome
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005840	cellular_component	ribosome
C	0006412	biological_process	translation
C	0022627	cellular_component	cytosolic small ribosomal subunit
C	1990904	cellular_component	ribonucleoprotein complex
d	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
d	0002181	biological_process	cytoplasmic translation
d	0003735	molecular_function	structural constituent of ribosome
d	0005737	cellular_component	cytoplasm
d	0005739	cellular_component	mitochondrion
d	0005829	cellular_component	cytosol
d	0005840	cellular_component	ribosome
d	0006412	biological_process	translation
d	0022627	cellular_component	cytosolic small ribosomal subunit
d	1990904	cellular_component	ribonucleoprotein complex
D	0000028	biological_process	ribosomal small subunit assembly
D	0002181	biological_process	cytoplasmic translation
D	0003735	molecular_function	structural constituent of ribosome
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0005840	cellular_component	ribosome
D	0006364	biological_process	rRNA processing
D	0006412	biological_process	translation
D	0022627	cellular_component	cytosolic small ribosomal subunit
D	0030490	biological_process	maturation of SSU-rRNA
D	0042274	biological_process	ribosomal small subunit biogenesis
D	1990145	biological_process	maintenance of translational fidelity
D	1990904	cellular_component	ribonucleoprotein complex
e	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
e	0005515	molecular_function	protein binding
e	0005634	cellular_component	nucleus
e	0005730	cellular_component	nucleolus
e	0005737	cellular_component	cytoplasm
e	0006364	biological_process	rRNA processing
e	0016973	biological_process	poly(A)+ mRNA export from nucleus
e	0030490	biological_process	maturation of SSU-rRNA
e	0030515	molecular_function	snoRNA binding
e	0030686	cellular_component	90S preribosome
e	0030688	cellular_component	preribosome, small subunit precursor
e	0042254	biological_process	ribosome biogenesis
E	0000054	biological_process	ribosomal subunit export from nucleus
E	0002181	biological_process	cytoplasmic translation
E	0003723	molecular_function	RNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
E	0015935	cellular_component	small ribosomal subunit
E	0022627	cellular_component	cytosolic small ribosomal subunit
E	0042254	biological_process	ribosome biogenesis
E	1990904	cellular_component	ribonucleoprotein complex
f	0000028	biological_process	ribosomal small subunit assembly
f	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
f	0003723	molecular_function	RNA binding
f	0003735	molecular_function	structural constituent of ribosome
f	0005737	cellular_component	cytoplasm
f	0005829	cellular_component	cytosol
f	0005840	cellular_component	ribosome
f	0006412	biological_process	translation
f	0008270	molecular_function	zinc ion binding
f	0022627	cellular_component	cytosolic small ribosomal subunit
f	0046872	molecular_function	metal ion binding
f	1990904	cellular_component	ribonucleoprotein complex
F	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F	0003723	molecular_function	RNA binding
F	0003735	molecular_function	structural constituent of ribosome
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005840	cellular_component	ribosome
F	0006412	biological_process	translation
F	0006413	biological_process	translational initiation
F	0022627	cellular_component	cytosolic small ribosomal subunit
F	0030686	cellular_component	90S preribosome
F	1990904	cellular_component	ribonucleoprotein complex
g	0002181	biological_process	cytoplasmic translation
g	0003735	molecular_function	structural constituent of ribosome
g	0005737	cellular_component	cytoplasm
g	0005829	cellular_component	cytosol
g	0005840	cellular_component	ribosome
g	0006412	biological_process	translation
g	0006451	biological_process	translational readthrough
g	0010494	cellular_component	cytoplasmic stress granule
g	0022627	cellular_component	cytosolic small ribosomal subunit
g	1990904	cellular_component	ribonucleoprotein complex
H	0000054	biological_process	ribosomal subunit export from nucleus
H	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H	0002181	biological_process	cytoplasmic translation
H	0003676	molecular_function	nucleic acid binding
H	0003723	molecular_function	RNA binding
H	0003735	molecular_function	structural constituent of ribosome
H	0005737	cellular_component	cytoplasm
H	0005739	cellular_component	mitochondrion
H	0005829	cellular_component	cytosol
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
H	0015935	cellular_component	small ribosomal subunit
H	0019843	molecular_function	rRNA binding
H	0022627	cellular_component	cytosolic small ribosomal subunit
H	1990904	cellular_component	ribonucleoprotein complex
I	0000028	biological_process	ribosomal small subunit assembly
I	0000054	biological_process	ribosomal subunit export from nucleus
I	0003723	molecular_function	RNA binding
I	0003735	molecular_function	structural constituent of ribosome
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0005840	cellular_component	ribosome
I	0006412	biological_process	translation
I	0022627	cellular_component	cytosolic small ribosomal subunit
I	0042254	biological_process	ribosome biogenesis
I	0042274	biological_process	ribosomal small subunit biogenesis
I	1990904	cellular_component	ribonucleoprotein complex
K	0002181	biological_process	cytoplasmic translation
K	0003735	molecular_function	structural constituent of ribosome
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0005840	cellular_component	ribosome
K	0006451	biological_process	translational readthrough
K	0022627	cellular_component	cytosolic small ribosomal subunit
K	1990904	cellular_component	ribonucleoprotein complex
L	0000028	biological_process	ribosomal small subunit assembly
L	0000054	biological_process	ribosomal subunit export from nucleus
L	0002181	biological_process	cytoplasmic translation
L	0003735	molecular_function	structural constituent of ribosome
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
L	0022627	cellular_component	cytosolic small ribosomal subunit
L	0030490	biological_process	maturation of SSU-rRNA
L	1900153	biological_process	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
L	1990904	cellular_component	ribonucleoprotein complex
N	0000028	biological_process	ribosomal small subunit assembly
N	0002109	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S)
N	0002181	biological_process	cytoplasmic translation
N	0003735	molecular_function	structural constituent of ribosome
N	0005515	molecular_function	protein binding
N	0005634	cellular_component	nucleus
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
N	0008270	molecular_function	zinc ion binding
N	0016567	biological_process	protein ubiquitination
N	0019941	biological_process	modification-dependent protein catabolic process
N	0022626	cellular_component	cytosolic ribosome
N	0022627	cellular_component	cytosolic small ribosomal subunit
N	0031386	molecular_function	protein tag activity
N	0042254	biological_process	ribosome biogenesis
N	0044391	cellular_component	ribosomal subunit
N	0046872	molecular_function	metal ion binding
N	1990145	biological_process	maintenance of translational fidelity
N	1990904	cellular_component	ribonucleoprotein complex
p	0000056	biological_process	ribosomal small subunit export from nucleus
p	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
p	0000472	biological_process	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
p	0003723	molecular_function	RNA binding
p	0005634	cellular_component	nucleus
p	0005730	cellular_component	nucleolus
p	0005737	cellular_component	cytoplasm
p	0030490	biological_process	maturation of SSU-rRNA
p	0030686	cellular_component	90S preribosome
p	0042134	molecular_function	rRNA primary transcript binding
p	0042254	biological_process	ribosome biogenesis
p	0042255	biological_process	ribosome assembly
p	0043248	biological_process	proteasome assembly
p	0051082	molecular_function	unfolded protein binding
P	0000028	biological_process	ribosomal small subunit assembly
P	0000054	biological_process	ribosomal subunit export from nucleus
P	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
P	0000461	biological_process	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
P	0002181	biological_process	cytoplasmic translation
P	0003735	molecular_function	structural constituent of ribosome
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0005840	cellular_component	ribosome
P	0006364	biological_process	rRNA processing
P	0006412	biological_process	translation
P	0010494	cellular_component	cytoplasmic stress granule
P	0015935	cellular_component	small ribosomal subunit
P	0022627	cellular_component	cytosolic small ribosomal subunit
P	0030686	cellular_component	90S preribosome
P	0042254	biological_process	ribosome biogenesis
P	1990904	cellular_component	ribonucleoprotein complex
Q	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Q	0002181	biological_process	cytoplasmic translation
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0022627	cellular_component	cytosolic small ribosomal subunit
Q	0030686	cellular_component	90S preribosome
Q	1990904	cellular_component	ribonucleoprotein complex
r	0000166	molecular_function	nucleotide binding
r	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
r	0003824	molecular_function	catalytic activity
r	0004672	molecular_function	protein kinase activity
r	0004674	molecular_function	protein serine/threonine kinase activity
r	0005515	molecular_function	protein binding
r	0005524	molecular_function	ATP binding
r	0005634	cellular_component	nucleus
r	0005737	cellular_component	cytoplasm
r	0005829	cellular_component	cytosol
r	0006468	biological_process	protein phosphorylation
r	0010494	cellular_component	cytoplasmic stress granule
r	0016301	molecular_function	kinase activity
r	0016740	molecular_function	transferase activity
r	0030490	biological_process	maturation of SSU-rRNA
r	0030688	cellular_component	preribosome, small subunit precursor
r	0042254	biological_process	ribosome biogenesis
r	0046830	biological_process	positive regulation of RNA import into nucleus
r	0046872	molecular_function	metal ion binding
r	0106310	molecular_function	protein serine kinase activity
R	0000054	biological_process	ribosomal subunit export from nucleus
R	0002181	biological_process	cytoplasmic translation
R	0003723	molecular_function	RNA binding
R	0003735	molecular_function	structural constituent of ribosome
R	0005515	molecular_function	protein binding
R	0005654	cellular_component	nucleoplasm
R	0005730	cellular_component	nucleolus
R	0005737	cellular_component	cytoplasm
R	0005829	cellular_component	cytosol
R	0005840	cellular_component	ribosome
R	0006364	biological_process	rRNA processing
R	0006412	biological_process	translation
R	0015935	cellular_component	small ribosomal subunit
R	0022627	cellular_component	cytosolic small ribosomal subunit
R	0032040	cellular_component	small-subunit processome
R	0042254	biological_process	ribosome biogenesis
R	0045903	biological_process	positive regulation of translational fidelity
R	0070181	molecular_function	small ribosomal subunit rRNA binding
R	1990904	cellular_component	ribonucleoprotein complex
S	0002181	biological_process	cytoplasmic translation
S	0003723	molecular_function	RNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0019843	molecular_function	rRNA binding
S	0022627	cellular_component	cytosolic small ribosomal subunit
S	0030686	cellular_component	90S preribosome
S	1990904	cellular_component	ribonucleoprotein complex
t	0000461	biological_process	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
t	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
t	0000479	biological_process	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
t	0003723	molecular_function	RNA binding
t	0003924	molecular_function	GTPase activity
t	0005515	molecular_function	protein binding
t	0005634	cellular_component	nucleus
t	0005730	cellular_component	nucleolus
t	0005737	cellular_component	cytoplasm
t	0030686	cellular_component	90S preribosome
t	0030688	cellular_component	preribosome, small subunit precursor
t	0042254	biological_process	ribosome biogenesis
t	0043021	molecular_function	ribonucleoprotein complex binding
T	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
T	0003735	molecular_function	structural constituent of ribosome
T	0005654	cellular_component	nucleoplasm
T	0005730	cellular_component	nucleolus
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0005840	cellular_component	ribosome
T	0006364	biological_process	rRNA processing
T	0006412	biological_process	translation
T	0022627	cellular_component	cytosolic small ribosomal subunit
T	0030686	cellular_component	90S preribosome
T	0032040	cellular_component	small-subunit processome
T	0042254	biological_process	ribosome biogenesis
T	1990904	cellular_component	ribonucleoprotein complex
U	0002181	biological_process	cytoplasmic translation
U	0003735	molecular_function	structural constituent of ribosome
U	0005654	cellular_component	nucleoplasm
U	0005730	cellular_component	nucleolus
U	0005737	cellular_component	cytoplasm
U	0005829	cellular_component	cytosol
U	0005840	cellular_component	ribosome
U	0006364	biological_process	rRNA processing
U	0006412	biological_process	translation
U	0022627	cellular_component	cytosolic small ribosomal subunit
U	0030686	cellular_component	90S preribosome
U	0032040	cellular_component	small-subunit processome
U	0042254	biological_process	ribosome biogenesis
U	0042274	biological_process	ribosomal small subunit biogenesis
U	1990904	cellular_component	ribonucleoprotein complex
V	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
V	0003735	molecular_function	structural constituent of ribosome
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	0022627	cellular_component	cytosolic small ribosomal subunit
V	0030686	cellular_component	90S preribosome
V	1990904	cellular_component	ribonucleoprotein complex
W	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
W	0003723	molecular_function	RNA binding
W	0003735	molecular_function	structural constituent of ribosome
W	0005515	molecular_function	protein binding
W	0005654	cellular_component	nucleoplasm
W	0005730	cellular_component	nucleolus
W	0005737	cellular_component	cytoplasm
W	0005829	cellular_component	cytosol
W	0005840	cellular_component	ribosome
W	0006364	biological_process	rRNA processing
W	0006412	biological_process	translation
W	0015935	cellular_component	small ribosomal subunit
W	0019843	molecular_function	rRNA binding
W	0022627	cellular_component	cytosolic small ribosomal subunit
W	0030476	biological_process	ascospore wall assembly
W	0030686	cellular_component	90S preribosome
W	0032040	cellular_component	small-subunit processome
W	0042254	biological_process	ribosome biogenesis
W	0042274	biological_process	ribosomal small subunit biogenesis
W	1990904	cellular_component	ribonucleoprotein complex
X	0000028	biological_process	ribosomal small subunit assembly
X	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
X	0003723	molecular_function	RNA binding
X	0003735	molecular_function	structural constituent of ribosome
X	0005737	cellular_component	cytoplasm
X	0005829	cellular_component	cytosol
X	0005840	cellular_component	ribosome
X	0006412	biological_process	translation
X	0019843	molecular_function	rRNA binding
X	0022627	cellular_component	cytosolic small ribosomal subunit
X	0030686	cellular_component	90S preribosome
X	1990904	cellular_component	ribonucleoprotein complex
Y	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Y	0002181	biological_process	cytoplasmic translation
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005730	cellular_component	nucleolus
Y	0005737	cellular_component	cytoplasm
Y	0005829	cellular_component	cytosol
Y	0005840	cellular_component	ribosome
Y	0006412	biological_process	translation
Y	0022627	cellular_component	cytosolic small ribosomal subunit
Y	0030686	cellular_component	90S preribosome
Y	0070181	molecular_function	small ribosomal subunit rRNA binding
Y	1990904	cellular_component	ribonucleoprotein complex
Z	0000028	biological_process	ribosomal small subunit assembly
Z	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Z	0002181	biological_process	cytoplasmic translation
Z	0003729	molecular_function	mRNA binding
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005654	cellular_component	nucleoplasm
Z	0005730	cellular_component	nucleolus
Z	0005737	cellular_component	cytoplasm
Z	0005829	cellular_component	cytosol
Z	0005840	cellular_component	ribosome
Z	0006364	biological_process	rRNA processing
Z	0006412	biological_process	translation
Z	0022627	cellular_component	cytosolic small ribosomal subunit
Z	0030686	cellular_component	90S preribosome
Z	0032040	cellular_component	small-subunit processome
Z	0042254	biological_process	ribosome biogenesis
Z	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KskIqDkegIPpdqQrLIFaGkqleD

Chain	Residue	Details
N	LYS27-ASP52

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site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDiVtVgQcRPIS

Chain	Residue	Details
X	GLY120-SER132

---

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GyvILTTSaGIMdheeAR

Chain	Residue	Details
b	GLY100-ARG117

---

site_id	PS01189
Number of Residues	19
Details	RIBOSOMAL_S12E Ribosomal protein S12e signature. ALKvvLrtAlvhDGLarGL

Chain	Residue	Details
D	ALA27-LEU45

---

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. LrALarS.GLrIgrieDvTPvPSD

Chain	Residue	Details
Z	LEU102-ASP124

---

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. VrkHLernRkDkdAkfrLilIesrihrLarY

Chain	Residue	Details
Y	VAL98-TYR128

---

site_id	PS00529
Number of Residues	23
Details	RIBOSOMAL_S24E Ribosomal protein S24e signature. FGggKSvGFGlVYNSvaeakkfE

Chain	Residue	Details
d	PHE64-GLU86

---

site_id	PS01168
Number of Residues	33
Details	RIBOSOMAL_S27E Ribosomal protein S27e signature. KCpgClnittvFShAqtavtCesCStiLctPtG

Chain	Residue	Details
f	LYS36-GLY68

---

site_id	PS00712
Number of Residues	16
Details	RIBOSOMAL_S17E Ribosomal protein S17e signature. IqSKrLRNkIAGYtTH

Chain	Residue	Details
C	ILE41-HIS56

---

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGhvSQvyAirqAiAKGL

Chain	Residue	Details
F	GLY71-LEU89

---

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KqPNSAiR

Chain	Residue	Details
c	LYS62-ARG69

---

site_id	PS00961
Number of Residues	9
Details	RIBOSOMAL_S28E Ribosomal protein S28e signature. ESEREARrL

Chain	Residue	Details
L	GLU58-LEU66

---

site_id	PS00578
Number of Residues	12
Details	RIBOSOMAL_S6E Ribosomal protein S6e signature. ISGGnDkqGfPM

Chain	Residue	Details
T	ILE52-MET63

---

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtqVYKlglAkSvhhARvLI

Chain	Residue	Details
W	LEU105-ILE129

---

site_id	PS00962
Number of Residues	12
Details	RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. AqLLLAANTHLG

Chain	Residue	Details
P	ALA14-GLY25

---

site_id	PS00963
Number of Residues	25
Details	RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PrlVIVtDprsDaqaIkEasyvNIP

Chain	Residue	Details
P	PRO118-PRO142

---

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GQrtrFkAvvVVGDsn.GhVGlGiktak.EVag.AI

Chain	Residue	Details
R	GLY93-ILE125

---

site_id	PS00996
Number of Residues	9
Details	RIBOSOMAL_S21E Ribosomal protein S21e signature. LYVPRKCSA

Chain	Residue	Details
a	LEU11-ALA19

---

site_id	PS00528
Number of Residues	15
Details	RIBOSOMAL_S4E Ribosomal protein S4e signature. HlKRLAaPhhWlLdK

Chain	Residue	Details
S	HIS8-LYS22

---

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGKafnqveIrpemLGhyLGEFsiT

Chain	Residue	Details
E	ASN98-THR122

---

site_id	PS01193
Number of Residues	20
Details	RIBOSOMAL_S8E Ribosomal protein S8e signature. RsaTGAkraqf.RkKrKfELG

Chain	Residue	Details
V	ARG11-GLY30

---

site_id	PS00948
Number of Residues	14
Details	RIBOSOMAL_S7E Ribosomal protein S7e signature. KLtRELEKKFQdRH

Chain	Residue	Details
U	LYS76-HIS89

---

site_id	PS00628
Number of Residues	20
Details	RIBOSOMAL_S19E Ribosomal protein S19e signature. PykhidaSgsInRkVLQaLE

Chain	Residue	Details
I	PRO90-GLU109

---

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. ErLtnsLMmngrnnGKKlkavrIIkhT

Chain	Residue	Details
B	GLU91-THR117

---

site_id	PS01191
Number of Residues	13
Details	RIBOSOMAL_S3AE Ribosomal protein S3Ae signature. LkGRVvEvCLaDL

Chain	Residue	Details
Q	LEU61-LEU73

---

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGiRHfwGlrVRGQ

Chain	Residue	Details
H	ARG123-GLN136

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	56
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"22106047","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	73
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	39
Details	Compositional bias: {"description":"Basic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17287358","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"17287358","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Modified residue: {"description":"N6-methyllysine; by RKM1","evidences":[{"source":"PubMed","id":"22522802","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	23
Details	Zinc finger: {"description":"C4-type"}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	3
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17287358","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	3
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"UniProtKB","id":"P62979","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"HAMAP-Rule","id":"MF_03015","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"10601260","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9298649","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	63
Details	Domain: {"description":"S5 DRBM","evidences":[{"source":"PROSITE-ProRule","id":"PRU00268","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	63
Details	Domain: {"description":"S4 RNA-binding"}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17330950","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"15665377","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"30609991","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	5
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	74
Details	Domain: {"description":"S4 RNA-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00182","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P05755","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"UniProtKB","id":"P05755","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	2
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"10601260","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"1544921","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	1
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"10601260","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	1
Details	Modified residue: {"description":"3,4-dihydroxyproline","evidences":[{"source":"PubMed","id":"24550462","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	22
Details	Zinc finger: {"description":"C4-type","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	1
Details	Modified residue: {"description":"S-methylcysteine","evidences":[{"source":"PubMed","id":"22650761","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	166
Details	Domain: {"description":"Bms1-type G","evidences":[{"source":"PROSITE-ProRule","id":"PRU01051","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	52
Details	Domain: {"description":"KH"}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	1
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---