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6EKJ

Crystal structure of mammalian Rev7 in complex with human Chromosome alignment-maintaining phosphoprotein 1

Functional Information from GO Data
ChainGOidnamespacecontents
A0000122biological_processnegative regulation of transcription by RNA polymerase II
A0000785cellular_componentchromatin
A0001558biological_processregulation of cell growth
A0002208biological_processsomatic diversification of immunoglobulins involved in immune response
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005680cellular_componentanaphase-promoting complex
A0005694cellular_componentchromosome
A0005737cellular_componentcytoplasm
A0005819cellular_componentspindle
A0005856cellular_componentcytoskeleton
A0006281biological_processDNA repair
A0006302biological_processdouble-strand break repair
A0007015biological_processactin filament organization
A0008432molecular_functionJUN kinase binding
A0010719biological_processnegative regulation of epithelial to mesenchymal transition
A0010944biological_processnegative regulation of transcription by competitive promoter binding
A0016035cellular_componentzeta DNA polymerase complex
A0033138biological_processpositive regulation of peptidyl-serine phosphorylation
A0035861cellular_componentsite of double-strand break
A0042177biological_processnegative regulation of protein catabolic process
A0042276biological_processerror-prone translesion synthesis
A0042772biological_processDNA damage response, signal transduction resulting in transcription
A0043247biological_processtelomere maintenance in response to DNA damage
A0045830biological_processpositive regulation of isotype switching
A0045893biological_processpositive regulation of DNA-templated transcription
A0051301biological_processcell division
A0061629molecular_functionRNA polymerase II-specific DNA-binding transcription factor binding
A0090090biological_processnegative regulation of canonical Wnt signaling pathway
A1904667biological_processnegative regulation of ubiquitin protein ligase activity
A2000042biological_processnegative regulation of double-strand break repair via homologous recombination
A2000048biological_processnegative regulation of cell-cell adhesion mediated by cadherin
A2001034biological_processpositive regulation of double-strand break repair via nonhomologous end joining
Functional Information from PDB Data
site_idAC1
Number of Residues10
Detailsbinding site for residue CXS A 301
ChainResidue
ALEU74
BSER331
ATHR152
AGLU154
AALA155
AARG158
AASN159
AGLN164
AILE166
ATRP171

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692
ChainResidueDetails
BSER344
BSER355

227561

PDB entries from 2024-11-20

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