6EIC
Crystal structure of Rv0183, a Monoglyceride Lipase from Mycobacterium Tuberculosis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004622 | molecular_function | phosphatidylcholine lysophospholipase A1 activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0046503 | biological_process | glycerolipid catabolic process |
| A | 0047372 | molecular_function | monoacylglycerol lipase activity |
| A | 0052151 | biological_process | symbiont-mediated activation of host apoptosis |
| B | 0004622 | molecular_function | phosphatidylcholine lysophospholipase A1 activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0046503 | biological_process | glycerolipid catabolic process |
| B | 0047372 | molecular_function | monoacylglycerol lipase activity |
| B | 0052151 | biological_process | symbiont-mediated activation of host apoptosis |
| C | 0004622 | molecular_function | phosphatidylcholine lysophospholipase A1 activity |
| C | 0005576 | cellular_component | extracellular region |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0046503 | biological_process | glycerolipid catabolic process |
| C | 0047372 | molecular_function | monoacylglycerol lipase activity |
| C | 0052151 | biological_process | symbiont-mediated activation of host apoptosis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 C 301 |
| Chain | Residue |
| C | LEU39 |
| C | LEU166 |
| C | HOH422 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MPD C 302 |
| Chain | Residue |
| C | LEU39 |
| C | GLU41 |
| C | HIS109 |
| C | SER110 |
| C | HIS256 |
| C | GLU257 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue MPD A 301 |
| Chain | Residue |
| A | LEU39 |
| A | HIS109 |
| A | SER110 |
| A | TYR181 |
| A | LEU228 |
| A | HIS256 |
| A | GLU257 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue MPD B 301 |
| Chain | Residue |
| B | GLY38 |
| B | LEU39 |
| B | ARG45 |
| B | HIS109 |
| B | TYR181 |
| B | HIS256 |
| B | GLU257 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue NO3 B 302 |
| Chain | Residue |
| B | LEU39 |
| B | LEU200 |
| B | HOH428 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"17784850","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"29895832","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"17784850","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"29895832","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
