Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004674 | molecular_function | protein serine/threonine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue B5E A 401 |
| Chain | Residue |
| A | LEU203 |
| A | ASP205 |
| A | LEU242 |
| A | GLU264 |
| A | LEU265 |
| A | ASP266 |
| A | PRO267 |
| A | ILE272 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residue B5E A 402 |
| Chain | Residue |
| A | GLY46 |
| A | ASN118 |
| A | TYR125 |
| A | PRO159 |
| A | HIS160 |
| A | VAL162 |
| A | MET163 |
| A | ILE164 |
| A | MET221 |
| A | SER224 |
| A | MET225 |
| A | LEU45 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | binding site for residue B5E A 403 |
| Chain | Residue |
| A | GLN36 |
| A | ASP37 |
| A | TYR39 |
| A | LEU41 |
| A | VAL101 |
| A | ASP103 |
| A | THR108 |
| A | ALA110 |
| B | GLU282 |
| B | PRO295 |
| B | LEU298 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue ACT A 404 |
| Chain | Residue |
| A | LYS68 |
| A | PHE113 |
| A | ILE174 |
| A | ASP175 |
| A | HOH518 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue B5E B 401 |
| Chain | Residue |
| B | ASP205 |
| B | GLU264 |
| B | LEU265 |
| B | PRO267 |
| site_id | AC6 |
| Number of Residues | 15 |
| Details | binding site for residue B5E B 402 |
| Chain | Residue |
| B | LEU45 |
| B | GLY46 |
| B | PHE121 |
| B | LEU124 |
| B | TYR125 |
| B | LEU128 |
| B | PRO159 |
| B | HIS160 |
| B | VAL162 |
| B | MET163 |
| B | ILE164 |
| B | MET221 |
| B | SER224 |
| B | MET225 |
| B | GLU230 |
| site_id | AC7 |
| Number of Residues | 11 |
| Details | binding site for residue B5E B 403 |
| Chain | Residue |
| A | ARG280 |
| A | GLU282 |
| A | VAL293 |
| A | SER294 |
| B | GLN36 |
| B | TYR39 |
| B | LEU41 |
| B | VAL101 |
| B | ASP103 |
| B | THR108 |
| B | ALA110 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue ACT B 404 |
| Chain | Residue |
| B | LYS68 |
| B | PHE113 |
| B | ILE174 |
| B | ASP175 |
| B | HOH521 |
| B | HOH537 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 33 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGRGKYSEVFeAinitnnekvvvkilkpv.AAAK |
| Chain | Residue | Details |
| A | LEU45-LYS77 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. ImHrDVKphNVMI |
| Chain | Residue | Details |
| A | ILE152-ILE164 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 570 |
| Details | Domain: {"description":"Protein kinase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Region: {"description":"Interaction with beta subunit","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
