Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 301 |
| Chain | Residue |
| A | TYR122 |
| A | GLN123 |
| A | PRO201 |
| A | SER202 |
| A | PRO203 |
| A | HOH443 |
| B | SER131 |
| B | ALA133 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 302 |
| Chain | Residue |
| A | ILE114 |
| A | GLN115 |
| A | ASP168 |
| A | PHE169 |
| A | LYS170 |
| A | HOH405 |
| A | HOH409 |
| A | ASN113 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 303 |
| Chain | Residue |
| A | SER129 |
| A | SER130 |
| A | LYS132 |
| A | EDO312 |
| A | HOH402 |
| B | GLU124 |
| B | LEU146 |
| B | THR148 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 304 |
| Chain | Residue |
| A | GLY43 |
| A | LYS44 |
| B | LEU89 |
| B | ARG110 |
| B | HOH471 |
| B | HOH500 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 305 |
| Chain | Residue |
| A | ARG39 |
| A | GLN40 |
| A | ASP41 |
| A | LYS44 |
| A | GLY45 |
| A | THR47 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 306 |
| Chain | Residue |
| A | SER30 |
| A | ALA31 |
| A | LYS70 |
| A | HOH615 |
| B | EDO311 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue EDO A 307 |
| Chain | Residue |
| A | PHE200 |
| A | PRO201 |
| A | SER202 |
| A | HOH449 |
| A | HOH453 |
| B | ARG64 |
| B | SER80 |
| B | THR81 |
| B | HOH422 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 308 |
| Chain | Residue |
| A | LEU46 |
| A | SER48 |
| A | HOH415 |
| A | HOH567 |
| B | LEU103 |
| B | HIS104 |
| B | PHE105 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 309 |
| Chain | Residue |
| A | ASP197 |
| A | PHE199 |
| A | HOH406 |
| A | HOH420 |
| A | HOH558 |
| B | PRO62 |
| B | GLY63 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 310 |
| Chain | Residue |
| A | SER127 |
| A | LYS128 |
| A | SER130 |
| A | HOH401 |
| A | HOH407 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 311 |
| Chain | Residue |
| A | ASN20 |
| A | ALA80 |
| A | HOH508 |
| A | HOH549 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 312 |
| Chain | Residue |
| A | SER130 |
| A | ASP131 |
| A | GOL303 |
| A | HOH402 |
| B | GLU124 |
| site_id | AD4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 313 |
| Chain | Residue |
| A | MET164 |
| A | SER166 |
| A | MET167 |
| A | HOH417 |
| A | HOH598 |
| B | SER168 |
| B | GLY169 |
| B | HOH511 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 315 |
| Chain | Residue |
| A | LYS111 |
| A | SER142 |
| A | GLN143 |
| B | TRP240 |
| site_id | AD6 |
| Number of Residues | 8 |
| Details | binding site for residue PG4 B 301 |
| Chain | Residue |
| B | SER197 |
| B | THR199 |
| B | PHE200 |
| B | ASN203 |
| B | ASN206 |
| B | HOH407 |
| B | HOH415 |
| B | HOH447 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 302 |
| Chain | Residue |
| B | ASN107 |
| B | GLY108 |
| B | ARG110 |
| B | HOH471 |
| B | HOH500 |
| B | ARG10 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 303 |
| Chain | Residue |
| B | GLN38 |
| B | THR39 |
| B | PRO40 |
| B | ARG110 |
| B | HOH472 |
| B | HOH529 |
| site_id | AD9 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 304 |
| Chain | Residue |
| A | ARG125 |
| B | PRO130 |
| B | TRP201 |
| B | ASP244 |
| B | HOH418 |
| B | HOH441 |
| B | HOH604 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 305 |
| Chain | Residue |
| A | GLU4 |
| A | THR6 |
| B | THR232 |
| B | HOH424 |
| B | HOH448 |
| site_id | AE2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 306 |
| Chain | Residue |
| B | GLU83 |
| B | GLY85 |
| B | ASP86 |
| B | HOH505 |
| site_id | AE3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 307 |
| Chain | Residue |
| B | LYS229 |
| B | HOH425 |
| B | HOH467 |
| site_id | AE4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO B 308 |
| Chain | Residue |
| A | PHE27 |
| A | SER72 |
| A | GLY73 |
| A | HOH473 |
| B | THR8 |
| B | PRO9 |
| B | ARG10 |
| B | HOH403 |
| site_id | AE5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 309 |
| Chain | Residue |
| B | THR8 |
| B | THR21 |
| B | SER23 |
| B | GLU76 |
| site_id | AE6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 310 |
| Chain | Residue |
| B | EDO312 |
| B | HOH405 |
| B | HOH470 |
| site_id | AE7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 311 |
| Chain | Residue |
| A | EDO306 |
| B | EDO313 |
| site_id | AE8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 312 |
| Chain | Residue |
| B | ASP97 |
| B | EDO310 |
| B | HOH409 |
| B | HOH416 |
| B | HOH470 |
| site_id | AE9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 313 |
| Chain | Residue |
| B | PHE70 |
| B | ASN72 |
| B | ARG74 |
| B | EDO311 |
| B | HOH412 |
| site_id | AF1 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 314 |
| Chain | Residue |
| B | ARG64 |
| B | THR81 |
| B | GLU83 |
| B | HOH422 |
| site_id | AF2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 315 |
| Chain | Residue |
| B | ASP116 |
| B | ASN118 |
| B | GLU222 |
| B | TRP223 |
| B | THR224 |
| B | GLN225 |
| site_id | AF3 |
| Number of Residues | 6 |
| Details | binding site for residues EDO A 314 and EDO A 316 |
| Chain | Residue |
| A | THR6 |
| A | ASN24 |
| A | SER26 |
| A | HOH466 |
| B | ARG10 |
| B | TYR215 |
| site_id | AF4 |
| Number of Residues | 6 |
| Details | binding site for residues EDO A 314 and EDO A 316 |
| Chain | Residue |
| A | THR6 |
| A | ASN24 |
| A | SER26 |
| A | HOH466 |
| B | ARG10 |
| B | TYR215 |
| site_id | AF5 |
| Number of Residues | 6 |
| Details | binding site for residues EDO A 314 and EDO A 316 |
| Chain | Residue |
| A | THR6 |
| A | ASN24 |
| A | SER26 |
| A | HOH466 |
| B | ARG10 |
| B | TYR215 |
| site_id | AF6 |
| Number of Residues | 6 |
| Details | binding site for residues EDO A 314 and EDO A 316 |
| Chain | Residue |
| A | THR6 |
| A | ASN24 |
| A | SER26 |
| A | HOH466 |
| B | ARG10 |
| B | TYR215 |
